The alterations of retinal vasculature detected on optical coherence tomography angiography associated with chronic obstructive pulmonary disease
ConclusionHypercapnia, respiratory acidosis, and chronic hypoxia associated with COPD may affect the macula and optic nerve, resulting in a serious decrease in vascular density, and OCTA can be a very important tool in the follow-up and treatment of these patients. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 11, 2022 Category: Respiratory Medicine Authors: Murat Serkan Songur, Yavuz Selim İntepe, Seray Aslan Bayhan, Hasan Ali Bayhan, Bülent Çiftçi, Mehmet Çıtırık Tags: ORIGINAL ARTICLE Source Type: research

Risk factors for chronic obstructive pulmonary disease in never ‐smokers: A systematic review
ConclusionsThere are few studies on COPD risk factors in never-smokers. More purpose-designed studies in this subpopulation are thus called for, including well-designed studies to specifically assess if indoor radon has any role on COPD onset. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 10, 2022 Category: Respiratory Medicine Authors: Ana Pando ‐Sandoval, Alberto Ruano‐Ravina, Cristina Candal‐Pedreira, Carlota Rodríguez‐García, Cristina Represas‐Represas, Rafael Golpe, Alberto Fernández‐Villar, Mónica Pérez‐Ríos Tags: REVIEW ARTICLE Source Type: research

Issue Information
No abstract is available for this article. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - February 7, 2022 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Graft dysfunction and rejection of lung transplant, a review on diagnosis and management
ConclusionPrimary graft dysfunction, surgical complications, immune rejection, infections, and neoplasms represent major posttransplant complications. As the main posttransplant survival limitation, chronic lung allograft dysfunction has a characteristic imaging presentation; nevertheless, the clinical and imaging manifestations are often complex and overlap, so it is essential to understand the temporal evolution of these complications to narrow the differential diagnosis for early treatment to improve prognosis. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 27, 2022 Category: Respiratory Medicine Authors: Haishuang Sun, Mei Deng, Wenhui Chen, Min Liu, Huaping Dai, Chen Wang Tags: REVIEW ARTICLE Source Type: research

Issue Information
No abstract is available for this article. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 27, 2022 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research

Open Access for The Clinical Respiratory Journal
(Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 27, 2022 Category: Respiratory Medicine Authors: Paul Jones, Chen Wang Tags: EDITORIAL Source Type: research

Mepolizumab improves work productivity, activity limitation, symptoms, and rescue medication use in severe eosinophilic asthma
AbstractPatients with severe eosinophilic asthma experience daily activity limitations and reduced productivity at work. Using anonymized individual patient-level data from two previously conducted randomized, double-blind, placebo-controlled studies (MENSA [GSK ID:115588/NCT01691521]; MUSCA [GSK ID:200862/NCT02281318]), we investigated the effect of mepolizumab on work productivity, activity limitation, symptoms, and rescue medication use. Patient-reported outcomes including Work Productivity and Activity Impairment –General Health (WPAI-GH) scores (impairment percentages, 0%–100%), global activity limitation (scale 1...
Source: The Clinical Respiratory Journal - January 26, 2022 Category: Respiratory Medicine Authors: Frank C. Albers, Daniel J. Bratton, Necdet B. Gunsoy, Sarah M. Cockle, Rafael Alfonso ‐Cristancho, Gert‐Jan Braunstahl Tags: BRIEF REPORT Source Type: research

Clinical characteristics of non ‐small cell lung cancer patients with EGFR mutations and ALK & ROS1 fusions
ConclusionsEGFR mutations were more likely to occur in non-smoking, stage III –IV, and female patients with lung adenocarcinoma, whereasALK&ROS1 gene fusions were more likely to occur in young patients with lung adenocarcinoma. Emphysema was less common in patients withEGFR mutations. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 26, 2022 Category: Respiratory Medicine Authors: Qinghua Liu, Qingyan Huang, Zhikang Yu, Heming Wu Tags: ORIGINAL ARTICLE Source Type: research

Krebs von den Lungen ‐6 levels in untreated idiopathic pulmonary fibrosis
ConclusionsIt is identified that serum KL-6 is a useful noninvasive biomarker to help improve the certainty of IPF diagnosis from other interstitial lung disease and assist evaluation of disease severity and prognosis. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 26, 2022 Category: Respiratory Medicine Authors: Dingyuan Jiang, Huijuan Xiao, Run Dong, Jing Geng, Bingbing Xie, Yanhong Ren, Huaping Dai Tags: ORIGINAL ARTICLE Source Type: research

Association between age, gender, body mass index, and pulmonary function in preoperative patients with lung cancer
ConclusionAge and sex were directed to pulmonary obstruction, and muscle strength as a mediator between sex and lung function was novel, and BMI adjusted the effects of small airway function on FVC. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 26, 2022 Category: Respiratory Medicine Authors: Weicheng Xu, Yakang Liu, Bin Zeng, Xinping Li Tags: ORIGINAL ARTICLE Source Type: research

Balance impairment and cognitive dysfunction in patients with chronic obstructive pulmonary disease under 65  years
ConclusionsBalance tests in patients with COPD under the age of 65 are significantly low when compared with healthy controls at the same age. Balance and cognitive functions are significantly associated with each other. It may be beneficial to perform balance and cognitive function tests earlier even at the beginning of the treatment period of COPD, and strategies should be planned to prevent the progression of functional losses. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 26, 2022 Category: Respiratory Medicine Authors: Melike Hanim Kaygusuz, Ozge Oral Tapan, Utku Tapan, Sebahat Genc Tags: ORIGINAL ARTICLE Source Type: research

Prevalence of tobacco smoking and its socioeconomic determinants
ConclusionsTobacco control efforts should be more focused on vulnerable groups of cigarette and hookah users in the southwest of Iran. Moreover, SES and reduction of health-related disparities and inequality should be considered a crucial concern in this regard. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 21, 2022 Category: Respiratory Medicine Authors: Hamideh Mahdaviazad, Reza Foroutan, Seyed Masoom Masoompour Tags: ORIGINAL ARTICLE Source Type: research

Clinical and pathological features of bronchiolitis obliterans requiring lung transplantation in paraneoplastic pemphigus associated with Castleman disease
ConclusionBO in PNP associated with CD had poor clinical outcomes. LT was preferable choice in end-stage BO when PNP and CD were controlled. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 21, 2022 Category: Respiratory Medicine Authors: Wenhui Chen, Ling Zhao, Lijuan Guo, Li Zhao, Hongtao Niu, Huifang Lian, Huaping Dai, Jingyu Chen, Chen Wang Tags: ORIGINAL ARTICLE Source Type: research

Risk assessment of venous thromboembolism and bleeding in COVID ‐19 patients
ConclusionCritically ill patients with COVID-19 suffered both a high risk of thrombosis and bleeding risks. More effective VTE prevention strategies based on an individual assessment of bleeding risks were necessary for critically ill patients with COVID-19. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 21, 2022 Category: Respiratory Medicine Authors: Lan Wang, Lan Zhao, Feng Li, Ji Liu, Li Zhang, Qiuhong Li, Jin Gu, Shuo Liang, Qinhua Zhao, Jinmin Liu, Jin ‐fu Xu Tags: ORIGINAL ARTICLE Source Type: research

Yield of chest computed tomography angiogram in cystic fibrosis patients with suspected pulmonary embolism
ConclusionThe prevalence of PE in CF patients undergoing CTPA for suspected PE was 4%, which is lower than predicted by the Revised Geneva Score. This may be due to a large overlap in the signs and symptoms of PE and exacerbations of CF lung disease. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - January 21, 2022 Category: Respiratory Medicine Authors: Kathleen Suzanne Mahan, Hamna Ahmad, Andrew George Keenan, Matthew Erren Prekker, Robert Ralph Kempainen Tags: ORIGINAL ARTICLE Source Type: research