DNA image cytometry of bronchial washing as a diagnostic adjunct to radial endobronchial ultrasound ‐guided sampling of peripheral lung lesions: A single center prospective study
ConclusionIn malignant PPLs, DNA-ICM combined with R-EBUS-guided sampling can improve diagnostic positivity compared with either method alone. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - December 12, 2023 Category: Respiratory Medicine Authors: Cuiyan Guo,
Qi Zhang,
Yan Hu,
Junfang Huang,
Shixuan Wang,
Guangfa Wang Tags: ORIGINAL ARTICLE Source Type: research
Blood regulator of G protein signalling 1 as a potential prognostic biomarker in surgical nonsmall cell lung cancer patients: Correlation with clinical features and survival
ConclusionElevated blood RGS1 correlates with LYN metastasis, neoadjuvant chemotherapy administration, worse DFS and OS, which might serve as a useful prognostic biomarker for surgical NSCLC patients. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - December 12, 2023 Category: Respiratory Medicine Authors: Liping Wang,
Hui Zhang,
Xinliang Gu,
Ying Wang Tags: ORIGINAL ARTICLE Source Type: research
A rare case of hepatoid adenocarcinoma of the lung
We report a case of hepatoid adenocarcinoma with the primary lesion located in the left upper lung. The patient was treated by four cycles of combined therapy, and the tumour had significantly reduced in size. Subsequent postoperative pathology proved that the patient had achieved a complete remission. AbstractHepatoid adenocarcinoma of the lung is a special type of primary origin in the lung with obvious pathological features and short survival time. However, standard treatment guidelines have not yet been established. Herein, we report a case of hepatoid adenocarcinoma with the primary lesion located in the left upper lu...
Source: The Clinical Respiratory Journal - December 11, 2023 Category: Respiratory Medicine Authors: Xuejian Sun,
Jialin Liu,
Ting Hu,
Yefan Wu,
Hao Zhang Tags: BRIEF REPORT Source Type: research
A prognostic signature for lung adenocarcinoma by five genes associated with chemotherapy in lung adenocarcinoma
ConclusionThe risk score model constructed by five genes is a potential prognostic biomarker for LUAD patients. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - December 10, 2023 Category: Respiratory Medicine Authors: Xiaofeng Li,
Chunwei Xu,
Yonghua Min,
Zhanqiang Zhai,
Youcai Zhu Tags: ORIGINAL ARTICLE Source Type: research
Uniportal thoracoscopic bullectomy with improved parietal pleurectomy for primary spontaneous pneumothorax
ConclusionsThe perioperative results of bullectomy with the improved pleurectomy technique are deemed satisfactory. The various technical steps attempted at our center are found to be feasible and safe, and they may contribute to reducing the rates of recurrence in PSP. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - December 4, 2023 Category: Respiratory Medicine Authors: Ningning Kang,
Hao Zheng,
Wei Ge,
Jin ‐Xiu Hu,
Wen Liu,
Ren‐Quan Zhang Tags: ORIGINAL ARTICLE Source Type: research
Menthol induces apoptosis and inhibits proliferation and migration of nonsmall cell lung carcinoma in vitro and in vivo through Akt pathway
ConclusionsMenthol could display an inhibitory effect on NSCLC cells through Akt signaling pathway, making it a potential target for NSCLC treatment. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - November 28, 2023 Category: Respiratory Medicine Authors: Zhiyu Liu,
Chunlin Li,
Ling Mu,
Haiyang Hu,
Xiong Qin Tags: ORIGINAL ARTICLE Source Type: research
Analysis of characteristics related to interstitial lung disease or pulmonary hypertension in patients with dermatomyositis
ConclusionILD-DM has higher IgG, IgA and IgM than that of Non-ILD-DM. PH-DM has higher IL-6, IL-10 and lower IL-17, DP cell ratio and B lymphocyte ratio than that of Non-PH-DM. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - November 21, 2023 Category: Respiratory Medicine Authors: Chulin Wang,
Han Yang,
Tongfen Li,
Yiqiong Wen,
Heran Yang,
Weifeng Tang,
Lin Li,
Shibo Sun Tags: ORIGINAL ARTICLE Source Type: research
Association of TOP2A and ADH1B with lipid levels and prognosis in patients with lung adenocarcinoma and squamous cell carcinoma
ConclusionsTOP2A andADH1B can be used as diagnostic markers for LUAD and LUSC, but only as independent prognostic factors for LUAD, and may be involved in lipid metabolism in LUAD patients but not in LUSC. Thus, combining genetic diagnostics with lipid panel tests might be an effective method for an early diagnosis and improved prognosis of LUAD. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - November 21, 2023 Category: Respiratory Medicine Authors: Dongdong Yin,
Yinci Zhang,
Hui Li,
Longqiang Cheng Tags: ORIGINAL ARTICLE Source Type: research
Prognostic gene HLA ‐DMA associated with cell cycle and immune infiltrates in LUAD
ConclusionThese results reveal that HLA-DMA might act as a biomarker for immune infiltration and immunotherapy response. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - November 17, 2023 Category: Respiratory Medicine Authors: Ya ‐jie Huang,
Jian‐kun He,
Xiaoyang Duan,
Ran Hou,
Jian Shi Tags: ORIGINAL ARTICLE Source Type: research
Cigarette smoke aggravates asthma via altering airways inflammation phenotypes and remodelling
ConclusionCSE inhibits OVA-induced AHR, changes inflammation ‘phenotypes’, while accelerates some aspects of airways remodelling, which might contribute to worse symptoms and be refractory to anti-inflammation therapies for asthmatics. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - November 15, 2023 Category: Respiratory Medicine Authors: Qiong Huang,
Yan Li,
Chenduo Li,
Xin Zhang,
Xiaonan Du,
Yan Chen,
Chris J. Corrigan,
Wei Wang,
Sun Ying Tags: ORIGINAL ARTICLE Source Type: research
Rationale and design of a multicenter, randomized phase II trial of durvalumab with or without multitarget tyrosine kinase inhibitor as maintenance treatment in extensive ‐stage small‐cell lung cancer patients (DURABLE study)
DiscussionWe conduct a phase II study to investigate the safety and efficacy of durvalumab combined with anlotinib as maintenance treatment in ES-SCLC patients. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - November 11, 2023 Category: Respiratory Medicine Authors: Bo Zhang,
Hua Zhong,
Chunlei Shi,
Zhiqiang Gao,
Runbo Zhong,
Aiqin Gu,
Weimin Wang,
Tianqing Chu,
Liwen Xiong,
Wei Zhang,
Huimin Wang,
Xueyan Zhang,
Baohui Han Tags: PROTOCOL Source Type: research
Issue Information
No abstract is available for this article. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - November 9, 2023 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research
Association between IL10 rs1800896 polymorphism and risk of pediatric asthma: A meta ‐analysis
ConclusionIn conclusion,IL10 rs1800896 polymorphism may be useful as a predictive marker for childhood asthma in Asians, although further studies are needed to validate the study results. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - November 8, 2023 Category: Respiratory Medicine Authors: Zhihong Zhou,
Hui Zhang,
Yuanhong Yuan Tags: ORIGINAL ARTICLE Source Type: research
Safety outcomes of salbutamol: A systematic review and meta ‐analysis
ConclusionThis meta-analysis indicated that salbutamol was associated with a very common risk of palpitations or tachycardia. Clinical vigilance and research efforts are needed to optimize the safe use of salbutamol. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 17, 2023 Category: Respiratory Medicine Authors: Lan ‐Hong Ma,
Li Jia,
Ling Bai Tags: ORIGINAL ARTICLE Source Type: research
MiR ‐23a‐3p alleviates cigarette smoke extract‐induced pulmonary vascular endothelial cell apoptosis by targeting DNAJB1 in emphysema
ConclusionMiR-23a-3p alleviated emphysema progression, which could inhibit CSE-induced PMVECs apoptosis by targeting DNAJB1. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 13, 2023 Category: Respiratory Medicine Authors: Ke Li,
Xianwei Ye,
Mei Xu,
Chuan Xu,
Ping Lu,
Jiayi Li,
Guohang Yuan,
Cheng Zhang Tags: ORIGINAL ARTICLE Source Type: research
