SCN4B inhibits the progression of lung adenocarcinoma and is associated with better prognosis
ConclusionSCN4B expresses higher in normal samples, and SCN4B is able to be an independent prognostic signature for LUAD patients. TAL1 and ERG may regulate the expression of SCN4B by binding its upstream sequences. Our research is valuable in improving the effectiveness of treatment in LUAD. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 12, 2023 Category: Respiratory Medicine Authors: Minting Ma,
Bin Guo,
Hongwei Lu,
Lei Hong Tags: ORIGINAL ARTICLE Source Type: research
Isolation of Epstein ‐Barr virus‐deoxyribonucleic acid in the lower respiratory tract for distinguishing critically ill patients from those with influenza‐associated pneumonia: A pilot study
ConclusionThe isolation rate of EBV in the lower respiratory tract was 46.9%. The length of hospital stays, intensive care unit admission rate, invasive mechanical ventilation rate, extracorporeal membrane oxygenation rate, SOFA score, and the proportion of moderate-to-severe ARDS in the EBV-positive group were higher than those in the EBV-negative group, while there was no effect on the death during hospitalization. The isolation of EBV in the lower respiratory tract and low lymphocyte count are independent risk factors for the development of moderate-to-severe ARDS in patients with influenza A-related pneumonia. (Source:...
Source: The Clinical Respiratory Journal - October 12, 2023 Category: Respiratory Medicine Authors: Yu Bai,
Yinqun Guo,
Xi Chen,
Chunxia Yang,
Li Gu Tags: ORIGINAL ARTICLE Source Type: research
Impact of selexipag use within 12 months of pulmonary arterial hypertension diagnosis on hospitalizations and medical costs: A retrospective cohort study
ConclusionSelexipag initiation within 12 months of PAH diagnosis demonstrated reductions in all-cause hospitalization rate and medical costs. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 8, 2023 Category: Respiratory Medicine Authors: Yuen Tsang,
Michael Stokes,
Yong ‐Jin Kim,
Rong Tilney,
Sumeet Panjabi Tags: ORIGINAL ARTICLE Source Type: research
Modified forced expiration technique using expiratory resistance in adults with cystic fibrosis
ConclusionCombining the FET with a PEP mask did not improve EOE and other outcomes in this small study. Investigating the efficacy of this technique within a larger population is warranted. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 5, 2023 Category: Respiratory Medicine Authors: Kathryn Watson,
Emma Koenig,
Ashleigh Bannister,
Virginia Mayne,
Angela Jacques,
Abbey Sawyer,
Jamie Wood Tags: BRIEF REPORT Source Type: research
Development of a nomogram to estimate the risk of community ‐acquired pneumonia in adults with acute asthma exacerbations
ConclusionsThe nomogram performed well in predicting the risk of CAP in hospitalized patients with AEs, thereby providing rapid guidance for clinical decision-making. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 5, 2023 Category: Respiratory Medicine Authors: Yufan Duan,
Dilixiati Nafeisa,
Mengyu Lian,
Jie Song,
Jingjing Yang,
Ziliang Hou,
Jinxiang Wang Tags: ORIGINAL ARTICLE Source Type: research
Issue Information
No abstract is available for this article. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - October 2, 2023 Category: Respiratory Medicine Tags: ISSUE INFORMATION Source Type: research
Study on the application of percutaneous closed pleural brushing combined with cell block technique in the diagnosis of malignant pleural effusion
ConclusionCompared with CPB, CPBR followed by the cell block technique can significantly increase the positive diagnostic rate of suspected MPE. CEA testing of pleural fluid after CPBR has a high predictive efficacy forEGFR mutation in lung adenocarcinoma patients with MPE, implying pleural fluid extracted for cell block after CPBR may be an ideal specimen for genetic testing. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 30, 2023 Category: Respiratory Medicine Authors: Kang Wang,
Xueting Hu,
Yufang Chen,
Xinglin Yi,
Xianfeng Han,
Duan Zhu,
Bingjing Zhu,
Hu Luo Tags: ORIGINAL ARTICLE Source Type: research
Classic biphasic pulmonary blastoma: A case report and review of the literature from 2000 to 2022
This report further in corporates a comprehensive review of CBPB literature from the past 22 years. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 29, 2023 Category: Respiratory Medicine Authors: Hui Yao,
Xin Jiang,
Ying Zeng,
Xue Wang,
Xuefeng Tang Tags: REVIEW ARTICLE Source Type: research
Deconvolution of bulk RNA sequencing in activated phosphoinositide 3 ‐kinase δ syndrome
ConclusionDeconvolution of bulk RNA sequencing to assess immune cells status can provide further insight into the alterations in immunological features underlying APDS and other rare diseases. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 28, 2023 Category: Respiratory Medicine Authors: Xia Huang,
Haiyan Gu Tags: BRIEF REPORT Source Type: research
Predicting in ‐hospital mortality in patients admitted from the emergency department for pulmonary embolism: Incidence and prognostic value of deep vein thrombosis. A retrospective study
ConclusionsAlthough further studies are needed to confirm the prognostic role of DVT at PE, involvement of the iliocaval venous axis should considered to be a sign of a higher risk of IHM and may be a key factor in prognostic stratification. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 20, 2023 Category: Respiratory Medicine Authors: Teresa Pagano,
Irma Sofia Fabbri,
Marcello Benedetto,
Luca D'Angelo,
Giorgio Galizia,
Andrea Portoraro,
Matteo Guarino,
Benedetta Perna,
Angelina Passaro,
Daniele Cariani,
Michele Domenico Spampinato,
Roberto De Giorgio Tags: ORIGINAL ARTICLE Source Type: research
PCV ‐VG combined individualized PEEP determination in one‐lung ventilated patients with PEEP step change direction: A randomized controlled trial
ConclusionGradient-directed altered PEEP titration could improve respiratory mechanics, arterial blood gases, and inflammatory responses and reduce the incidence of PPCs in patients undergoing thoracoscopic surgery. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 19, 2023 Category: Respiratory Medicine Authors: Guowei Li,
Saixian Ma,
Qian Shu,
Zhuhong Fang,
Zhiwen Yan,
Bo Si Tags: ORIGINAL ARTICLE Source Type: research
Development and validation of the CAIL prognostic score in non ‐small cell lung cancer patients with malignant pleural effusion
ConclusionsFor NSCLC patients with MPE, the validated CAIL prognostic score integrates clinical characteristics and therapeutic modalities to predict survival. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 19, 2023 Category: Respiratory Medicine Authors: Tianyuan Li,
Panwen Tian,
Qin Huang,
Hao Zeng,
Qi Wei,
Yalun Li Tags: ORIGINAL ARTICLE Source Type: research
Comparative analysis of methodologies for predicting overall survival in patients with non ‐small cell lung cancer based on the number and rate of resected positive lymph nodes: A study based on the SEER database for 2010 through 2019
ConclusionsOur results demonstrate that nPLN and LNR classifications may offer improved prognostic performance compared with the current N classification for LN-positive NSCLC patients. Nonetheless, more studies are needed to assess the feasibility of incorporating these classifications into the next TNM staging system. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 19, 2023 Category: Respiratory Medicine Authors: Qiang Guo,
Sheng Hu,
Silin Wang,
Lang Su,
Wenxiong Zhang,
Jianjun Xu,
Yiping Wei Tags: ORIGINAL ARTICLE Source Type: research
Differences in chronic obstructive pulmonary disease among US nursing home residents with heart failure according to sex and type of heart failure
ConclusionsCOPD is highly prevalent among medically complex middle-aged and older nursing home residents with heart failure. Future research should focus on increasing our understanding of factors that influence the risk and optimal management of COPD and heart failure to improve the quality of life for nursing home residents. (Source: The Clinical Respiratory Journal)
Source: The Clinical Respiratory Journal - September 16, 2023 Category: Respiratory Medicine Authors: Seun Osundolire,
Robert J. Goldberg,
Kate L. Lapane Tags: ORIGINAL ARTICLE Source Type: research
A case report of rib osteosarcoma and literature review
Osteosarcoma of the ribs is very rare. Here, we report a case of primary osteosarcoma of the ribs in an adolescent girl. The patient underwent complete resection of the rib mass, and the mass was histopathologically diagnosed as chondroblastic osteosarcoma. After surgery, the patient received adjuvant chemotherapy and has no evidence of recurrence. AbstractAbout half of osteosarcomas occur near the knee joint, but other sites such as the humerus, upper femur, fibula, spine, and ilium can also occur. However, rib osteosarcoma is rarely reported. Here, we report the case of a 17-year-old female who was found to have a left d...
Source: The Clinical Respiratory Journal - September 15, 2023 Category: Respiratory Medicine Authors: Xiaofeng Hu,
Tianyi Bao,
Chao Yan,
Yongliang Zhu,
Xiaofei Zheng Tags: BRIEF REPORT Source Type: research
