Intergenerational Effects of the Fast Track Intervention on Next-Generation Child Outcomes: A Preregistered Randomized Clinical Trial
CONCLUSIONS: Fast Track was associated with lower use of general inpatient services and inpatient and outpatient mental health services intergenerationally, but effects on parent-reported mental health of the children were not apparent across generations. Investing in interventions for the mental health of children could reduce service use burdens across generations.PMID:38321914 | DOI:10.1176/appi.ajp.20220927 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 7, 2024 Category: Psychiatry Authors: W Andrew Rothenberg Jennifer E Lansford Jennifer W Godwin Kenneth A Dodge William E Copeland Candice L Odgers Robert J McMahon Anna Rybinska Conduct Problems Prevention Research Group Source Type: research

Cognitive Outcomes After Antidepressant Pharmacotherapy for Late-Life Depression: A Systematic Review and Meta-Analysis
CONCLUSION: Antidepressant pharmacotherapy of LLD appears to improve certain domains of cognitive function, particularly memory and learning. This effect may be mediated by an improvement in depressive symptoms. Studies comparing individuals receiving pharmacotherapy with untreated control participants are needed.PMID:38321915 | DOI:10.1176/appi.ajp.20230392 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 7, 2024 Category: Psychiatry Authors: Nicholas J Ainsworth Tulip Marawi Marta M Maslej Daniel M Blumberger Mary Pat McAndrews Argyrios Perivolaris Bruce G Pollock Tarek K Rajji Benoit H Mulsant Source Type: research

Treatment Response Prediction in Major Depressive Disorder Using Multimodal MRI and Clinical Data: Secondary Analysis of a Randomized Clinical Trial
CONCLUSIONS: The study results confirm that early sertraline treatment response can be predicted; that the models are sertraline specific compared with placebo; that prediction benefits from integrating multimodal MRI data with clinical data; and that perfusion imaging contributes most to these predictions. Using this approach, a lean and effective protocol could individualize sertraline treatment planning to improve psychiatric care.PMID:38321916 | DOI:10.1176/appi.ajp.20230206 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 7, 2024 Category: Psychiatry Authors: Maarten G Poirot Henricus G Ruhe Henk-Jan M M Mutsaerts Ivan I Maximov Inge R Groote Atle Bj ørnerud Henk A Marquering Liesbeth Reneman Matthan W A Caan Source Type: research

Intergenerational Effects of the Fast Track Intervention on Next-Generation Child Outcomes: A Preregistered Randomized Clinical Trial
CONCLUSIONS: Fast Track was associated with lower use of general inpatient services and inpatient and outpatient mental health services intergenerationally, but effects on parent-reported mental health of the children were not apparent across generations. Investing in interventions for the mental health of children could reduce service use burdens across generations.PMID:38321914 | DOI:10.1176/appi.ajp.20220927 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 7, 2024 Category: Psychiatry Authors: W Andrew Rothenberg Jennifer E Lansford Jennifer W Godwin Kenneth A Dodge William E Copeland Candice L Odgers Robert J McMahon Anna Rybinska Conduct Problems Prevention Research Group Source Type: research

Cognitive Outcomes After Antidepressant Pharmacotherapy for Late-Life Depression: A Systematic Review and Meta-Analysis
CONCLUSION: Antidepressant pharmacotherapy of LLD appears to improve certain domains of cognitive function, particularly memory and learning. This effect may be mediated by an improvement in depressive symptoms. Studies comparing individuals receiving pharmacotherapy with untreated control participants are needed.PMID:38321915 | DOI:10.1176/appi.ajp.20230392 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 7, 2024 Category: Psychiatry Authors: Nicholas J Ainsworth Tulip Marawi Marta M Maslej Daniel M Blumberger Mary Pat McAndrews Argyrios Perivolaris Bruce G Pollock Tarek K Rajji Benoit H Mulsant Source Type: research