Subcortico-Cortical Dysconnectivity in ADHD: A Voxel-Wise Mega-Analysis Across Multiple Cohorts
CONCLUSIONS: The findings from this large-scale mega-analysis support established links with subcortico-cortical circuits, which were robust to potential confounders. However, effect sizes were small, and it seems likely that resting-state subcortico-cortical connectivity can capture only a fraction of the complex pathophysiology of ADHD.PMID:38476041 | DOI:10.1176/appi.ajp.20230026 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 13, 2024 Category: Psychiatry Authors: Luke J Norman Gustavo Sudre Jolie Price Philip Shaw Source Type: research
Sex-Specific Distributed White Matter Microarchitectural Alterations in Preadolescent Youths With Anxiety Disorders: A Mega-Analytic Study
CONCLUSIONS: In addition to confirming male-specific anxiety disorder-related reductions in UF FA, the results demonstrate that anxiety disorders in boys and not girls are associated with broadly distributed WM alterations across the brain. These findings support further studies focused on understanding the extent to which WM alterations in boys with anxiety disorders are involved in pathophysiological processes that mediate anxiety disorders. The findings also suggest the possibility that WM microarchitecture could serve as a novel treatment target for childhood anxiety disorders.PMID:38476042 | DOI:10.1176/appi.ajp.20221...
Source: The American Journal of Psychiatry - March 13, 2024 Category: Psychiatry Authors: Nakul Aggarwal Do P M Tromp Jennifer U Blackford Daniel S Pine Patrick H Roseboom Lisa E Williams Ned H Kalin Source Type: research
Durability of Effects of Cognitive Remediation on Cognition and Psychosocial Functioning in Schizophrenia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials
CONCLUSIONS: Cognitive remediation provides durable improvements in cognition and functioning in schizophrenia. This finding corroborates the notion that cognitive remediation should be implemented more widely in clinical and rehabilitation practice.PMID:38476043 | DOI:10.1176/appi.ajp.20230396 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 13, 2024 Category: Psychiatry Authors: Antonio Vita Stefano Barlati Anna Ceraso Gabriele Nibbio Francesca Durante Michele Facchi Giacomo Deste Til Wykes Source Type: research
Neuromelanin-Sensitive MRI as Candidate Marker for Treatment Resistance in First-Episode Schizophrenia
CONCLUSIONS: These findings provide further evidence for dopaminergic differences between medication responders and nonresponders and support the potential of NM-MRI as a clinically applicable marker for treatment resistance in schizophrenia.PMID:38476044 | DOI:10.1176/appi.ajp.20220780 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 13, 2024 Category: Psychiatry Authors: Marieke van der Pluijm Kenneth Wengler Pascalle N Reijers Clifford M Cassidy Kaithlyn Tjong Tjin Joe Olav R de Peuter Guillermo Horga Jan Booij Lieuwe de Haan Elsmarieke van de Giessen Source Type: research
Reciprocal Effects Between Negative Parenting and Children's Callous-Unemotional Traits From Mid to Late Childhood
CONCLUSIONS: In mid-to-late childhood, genetic factors strongly influenced the development of CU traits, whereas environmental effects of negative parenting were small. Negative parenting was also relatively unaffected by CU traits. The small reciprocal effects originated mostly from genetic and shared environmental factors. Therefore, repeated intensive interventions addressing multiple risk factors rather than negative parenting alone may be best positioned to support families of children with CU traits across development.PMID:38476045 | DOI:10.1176/appi.ajp.20230208 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 13, 2024 Category: Psychiatry Authors: Patrizia Pezzoli Jean-Baptiste Pingault Margherita Malanchini Ivan Voronin Eamon McCrory Pasco Fearon Essi Viding Source Type: research
Reduction in Trauma-Related Symptoms After Anesthetic-Induced Intra-Operative Dreaming
Am J Psychiatry. 2024 Mar 13:appiajp20230698. doi: 10.1176/appi.ajp.20230698. Online ahead of print.NO ABSTRACTPMID:38476046 | DOI:10.1176/appi.ajp.20230698 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 13, 2024 Category: Psychiatry Authors: Laura M Hack Pilleriin Sikka Kelly Zhou Makoto Kawai Harrison S Chow Boris Heifets Source Type: research
Multimodal Predictors of Treatment Response in Major Depressive Disorder: Advancing Personalized Medicine in Psychiatry
Am J Psychiatry. 2024 Mar 1;181(3):180-182. doi: 10.1176/appi.ajp.20231025.NO ABSTRACTPMID:38425254 | DOI:10.1176/appi.ajp.20231025 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2024 Category: Psychiatry Authors: Mary L Phillips Source Type: research
Current and Future Approaches to Pediatric Anxiety Disorder Treatment
Am J Psychiatry. 2024 Mar 1;181(3):189-200. doi: 10.1176/appi.ajp.20231037.ABSTRACTThis overview critically appraises the literature on the treatment of pediatric anxiety disorders. The two established treatments for these conditions comprise cognitive-behavioral therapy (CBT) and antidepressant medications. Many youths receiving these treatments fail to achieve remission, which creates a need for new treatments. After summarizing the literature on CBT and currently available medications, the authors describe research that lays a foundation for improvements in the treatment of pediatric anxiety disorders. This foundation l...
Source: The American Journal of Psychiatry - March 1, 2024 Category: Psychiatry Authors: Andre Zugman Anderson M Winkler Purnima Qamar Daniel S Pine Source Type: research
The Fast Track Intervention: What Happens Down the River?
Am J Psychiatry. 2024 Mar 1;181(3):178-179. doi: 10.1176/appi.ajp.20231021.NO ABSTRACTPMID:38425256 | DOI:10.1176/appi.ajp.20231021 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2024 Category: Psychiatry Authors: Philip C Kendall Sophie Martel Marisa Meyer Dominique S McKnight Source Type: research
Late-Life Depression, Antidepressant Treatment, and Cognition: The Short Haul and the Long Haul
Am J Psychiatry. 2024 Mar 1;181(3):183-185. doi: 10.1176/appi.ajp.20231022.NO ABSTRACTPMID:38425257 | DOI:10.1176/appi.ajp.20231022 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2024 Category: Psychiatry Authors: David C Steffens Source Type: research
Setting the Record Straight on Long-Term Use, Dose Escalation, and Potential Misuse of Prescription Benzodiazepines
Am J Psychiatry. 2024 Mar 1;181(3):186-188. doi: 10.1176/appi.ajp.20240030.NO ABSTRACTPMID:38425258 | DOI:10.1176/appi.ajp.20240030 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2024 Category: Psychiatry Authors: Stephen B Soumerai Mahnum Shahzad Carl Salzman Source Type: research
New Insights into Treatments Across the Lifespan
Am J Psychiatry. 2024 Mar 1;181(3):171-174. doi: 10.1176/appi.ajp.20240051.NO ABSTRACTPMID:38425259 | DOI:10.1176/appi.ajp.20240051 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2024 Category: Psychiatry Authors: Ned H Kalin Source Type: research
Can Cognitive-Behavioral Therapy Normalize Neural Function in Youths With Pediatric Anxiety Disorders? A Developmental Neuroscience Perspective
Am J Psychiatry. 2024 Mar 1;181(3):175-177. doi: 10.1176/appi.ajp.20240024.NO ABSTRACTPMID:38425260 | DOI:10.1176/appi.ajp.20240024 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2024 Category: Psychiatry Authors: Cecile D Ladouceur Source Type: research
Correction to Rosenqvist et al
Am J Psychiatry. 2024 Mar 1;181(3):254. doi: 10.1176/appi.ajp.20230075correction.NO ABSTRACTPMID:38425261 | DOI:10.1176/appi.ajp.20230075correction (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2024 Category: Psychiatry Source Type: research
Multimodal Predictors of Treatment Response in Major Depressive Disorder: Advancing Personalized Medicine in Psychiatry
Am J Psychiatry. 2024 Mar 1;181(3):180-182. doi: 10.1176/appi.ajp.20231025.NO ABSTRACTPMID:38425254 | DOI:10.1176/appi.ajp.20231025 (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2024 Category: Psychiatry Authors: Mary L Phillips Source Type: research
