The Brain Feels the Pain From Teenage Drinking.
PMID: 29606060 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - April 1, 2018 Category: Psychiatry Authors: Stewart JL Tags: Am J Psychiatry Source Type: research

On the Couch: A Repressed History of the Analytic Couch From Plato to Freudby Nathan Kravis, M.D. Cambridge, Mass., MIT Press, 2017, 224 pp., $29.95 (hardcover).
PMID: 29606061 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - April 1, 2018 Category: Psychiatry Authors: Blumenthal E Tags: Am J Psychiatry Source Type: research

Increasing Male Preponderance in Suicide Coinciding With a Reduction by Half in Total Suicides in the Danish Population Should Raise Awareness of Male Depression.
rd SD PMID: 29606062 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - April 1, 2018 Category: Psychiatry Authors: Østergaard SD Tags: Am J Psychiatry Source Type: research

Contraceptive Conundrum: Use of Hormonal Contraceptives Is Associated With an Increased Risk of Suicide Attempt and Suicide.
PMID: 29606063 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - April 1, 2018 Category: Psychiatry Authors: Brent D Tags: Am J Psychiatry Source Type: research

Ketamine: Quo Vadis?
PMID: 29606064 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - April 1, 2018 Category: Psychiatry Authors: Nemeroff CB Tags: Am J Psychiatry Source Type: research

Disclosure of Editors' Financial Relationships.
Authors: PMID: 29606065 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - April 1, 2018 Category: Psychiatry Tags: Am J Psychiatry Source Type: research

Substance-Induced Psychosis: An Indicator of Development of Primary Psychosis?
PMID: 29606066 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - April 1, 2018 Category: Psychiatry Authors: Ghose S Tags: Am J Psychiatry Source Type: research

Treatment for Patients With a Functional Neurological Disorder (Conversion Disorder): An Integrated Approach.
PMID: 29606068 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - April 1, 2018 Category: Psychiatry Authors: O'Neal MA, Baslet G Tags: Am J Psychiatry Source Type: research

The Cats of Louis Wain: A Thousand Ways to Draw One's Mind.
PMID: 29606069 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - April 1, 2018 Category: Psychiatry Authors: Damiani S, Fusar-Poli L Tags: Am J Psychiatry Source Type: research

Molecular Pathogenicity of Anti-NMDA Receptor Autoantibody From Patients With First-Episode Psychosis.
r M, Groc L PMID: 29606071 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - April 1, 2018 Category: Psychiatry Authors: Jézéquel J, Lepleux M, Kahn RS, Honnorat J, Leboyer M, Groc L Tags: Am J Psychiatry Source Type: research

A Twin Study of Normative Personality and DSM-IV Personality Disorder Criterion Counts: Evidence for Separate Genetic Influences.
CONCLUSIONS: The results indicate that a moderate-to-sizable proportion of the genetic influence underlying DSM-IV personality disorders is not shared with the domain constructs of the Big Five model of normative personality. Caution should be exercised in assuming that normative personality measures can serve as proxies for DSM personality disorders when investigating the etiology of these disorders. PMID: 29558815 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 21, 2018 Category: Psychiatry Authors: Czajkowski N, Aggen SH, Krueger RF, Kendler KS, Neale MC, Knudsen GP, Gillespie NA, Røysamb E, Tambs K, Reichborn-Kjennerud T Tags: Am J Psychiatry Source Type: research

Prenatal Primary Prevention of Mental Illness by Micronutrient Supplements in Pregnancy.
Abstract Genes, infection, malnutrition, and other factors affecting fetal brain development are a major component of risk for a child's emotional development and later mental illnesses, including schizophrenia, bipolar disorder, and autism. Prenatal interventions to ameliorate that risk have yet to be established for clinical use. A systematic review of prenatal nutrients and childhood emotional development and later mental illness was performed. Randomized trials of folic acid, phosphatidylcholine, and omega-3 fatty acid supplements assess effects of doses beyond those adequate to remedy deficiencies to promote ...
Source: The American Journal of Psychiatry - March 21, 2018 Category: Psychiatry Authors: Freedman R, Hunter SK, Hoffman MC Tags: Am J Psychiatry Source Type: research

Developmental Trajectories of the Orbitofrontal Cortex and Anhedonia in Middle Childhood and Risk for Substance Use in Adolescence in a Longitudinal Sample of Depressed and Healthy Preschoolers.
CONCLUSIONS: The findings suggest that the development of the orbitofrontal cortex during childhood is strongly linked to experiences of anhedonia and that these growth trajectories predict substance use during a developmentally critical period. PMID: 29558817 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 21, 2018 Category: Psychiatry Authors: Luby JL, Agrawal A, Belden A, Whalen D, Tillman R, Barch DM Tags: Am J Psychiatry Source Type: research

Revisiting Antipsychotic Drug Actions Through Gene Networks Associated With Schizophrenia.
CONCLUSIONS: The network medicine approach provides a platform to collate information of disease genetics and drug-gene interactions to shift focus from development of antipsychotics to multitarget antischizophrenia drugs. This approach is transferable to other diseases. PMID: 29495895 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 2, 2018 Category: Psychiatry Authors: Kauppi K, Rosenthal SB, Lo MT, Sanyal N, Jiang M, Abagyan R, McEvoy LK, Andreassen OA, Chen CH Tags: Am J Psychiatry Source Type: research

Polygenic Risk Score for Alzheimer's Disease: Implications for Memory Performance and Hippocampal Volumes in Early Life.
CONCLUSIONS: Genetic risk for Alzheimer's disease may affect early-life cognition and hippocampal volumes, as shown in two independent samples. These data support previous evidence that some forms of late-life dementia may represent developmental conditions with roots in childhood. This result may vary depending on a sample's genetic risk and may be specific to some types of memory tasks. PMID: 29495896 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 2, 2018 Category: Psychiatry Authors: Axelrud LK, Santoro ML, Pine DS, Talarico F, Gadelha A, Manfro GG, Pan PM, Jackowski A, Picon F, Brietzke E, Grassi-Oliveira R, Bressan RA, Miguel EC, Rohde LA, Hakonarson H, Pausova Z, Belangero S, Paus T, Salum GA Tags: Am J Psychiatry Source Type: research

Effectiveness of Early Psychosis Intervention: Comparison of Service Users and Nonusers in Population-Based Health Administrative Data.
CONCLUSIONS: People with first-episode psychosis who used EPI services had mortality rates that were four times lower than those with first-episode psychosis who did not use these services, as well as better outcomes across several health care system indicators. These findings support the effectiveness of EPI services for the treatment of first-episode psychosis in the larger context of the overall health care system. PMID: 29495897 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 2, 2018 Category: Psychiatry Authors: Anderson KK, Norman R, MacDougall A, Edwards J, Palaniyappan L, Lau C, Kurdyak P Tags: Am J Psychiatry Source Type: research

Molecular Genetic Analysis Subdivided by Adversity Exposure Suggests Etiologic Heterogeneity in Major Depression.
CONCLUSIONS: The genetic contributions to major depression may differ between women with and those without major adverse life events. These results have implications for the molecular dissection of major depression and other complex psychiatric and biomedical diseases. PMID: 29495898 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 2, 2018 Category: Psychiatry Authors: Peterson RE, Cai N, Dahl AW, Bigdeli TB, Edwards AC, Webb BT, Bacanu SA, Zaitlen N, Flint J, Kendler KS Tags: Am J Psychiatry Source Type: research

Cortical Thinning and Neuropsychiatric Outcomes in Children Exposed to Prenatal Adversity: A Role for Placental CRH?
CONCLUSIONS: In view of the established effects of CRH on maturation and arborization of cortical neurons, and the major contribution of dendrites to cortical volume, these findings position pCRH as an important mediator of the consequences of early-life adversity on neuropsychiatric outcomes. PMID: 29495899 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 2, 2018 Category: Psychiatry Authors: Sandman CA, Curran MM, Davis EP, Glynn LM, Head K, Baram TZ Tags: Am J Psychiatry Source Type: research

Cannabidiol, an Adjunct Player in the Antipsychosis Arsenal.
PMID: 29490489 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Bassir Nia A, Hurd YL Tags: Am J Psychiatry Source Type: research

Suicide Rates, Psychiatric Hospital Bed Numbers, and Unemployment Rates From 1999 to 2015: A Population-Based Study in Hong Kong.
PMID: 29490490 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Lee EHM, Hui CLM, Chan PY, Chang WC, Chan SKW, Chen EYH Tags: Am J Psychiatry Source Type: research

Understanding Pregnancy's Protective Effect on Drug Use Within a Developmental Framework.
PMID: 29490492 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Massey SH, Wisner KL Tags: Am J Psychiatry Source Type: research

Treating Sleep Problems: A Transdiagnostic Approachby Allison G. Harvey, Ph.D., and Daniel J. Buysse, M.D. New York, Guilford, 2017, 192 pp., $25.50 (paperback).
PMID: 29490493 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Mellman T Tags: Am J Psychiatry Source Type: research

A Geriatrics Perspective on Dementia Prevention and Treatment.
PMID: 29490494 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Steffens DC Tags: Am J Psychiatry Source Type: research

Internet-Based Psychotherapy: How Far Can We Go?
PMID: 29490495 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Kocsis JH Tags: Am J Psychiatry Source Type: research

Corticotropin-Releasing Hormone Binding Protein: Stress, Psychopathology, and Antidepressant Treatment Response.
PMID: 29490496 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Kalin NH Tags: Am J Psychiatry Source Type: research

Psychiatrists in Combat: Mental Health Clinicians' Experiences in the War Zoneedited by Elspeth Cameron Ritchie, Christopher H. Warner, and Robert N. McLay. New York, Springer, 2017, 221 pp., $109.00 (paperback).
PMID: 29490497 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Hafter Gray S Tags: Am J Psychiatry Source Type: research

Medical Marijuana and the Opioid Epidemic: Response to Theriault and Schlesinger.
PMID: 29490498 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Olfson M, Wall MM, Blanco C Tags: Am J Psychiatry Source Type: research

Potential Impact of Medical Marijuana on Nonmedical Opioid Use.
PMID: 29490499 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Theriault BM, Schlesinger JJ Tags: Am J Psychiatry Source Type: research

The Mental Health Mission Aboard the USNS Comfort During Humanitarian Operations in Puerto Rico.
PMID: 29490500 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Schalk SK, Hendrix SR, Nissan DA Tags: Am J Psychiatry Source Type: research

Therapeutic Potential of Physical Exercise in Early Psychosis.
PMID: 29490501 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - March 1, 2018 Category: Psychiatry Authors: Noordsy DL, Burgess JD, Hardy KV, Yudofsky LM, Ballon JS Tags: Am J Psychiatry Source Type: research

Optimizing the Pharmacologic Treatment of Individuals With First-Episode Psychosis.
PMID: 29385823 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2018 Category: Psychiatry Authors: Goff DC Tags: Am J Psychiatry Source Type: research

The Psychoses of Menstruation and Childbearingby Ian Brockington, M.D., F.R.C.P. Cambridge, England, Cambridge University Press, 2017, 391 pp., $140.00 (hardcover).
PMID: 29385824 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2018 Category: Psychiatry Authors: Payne JL Tags: Am J Psychiatry Source Type: research

The Impact of Underpowered Studies on Clinical Trial Results.
PMID: 29385825 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2018 Category: Psychiatry Authors: Khan A, Fahl Mar K, Brown WA Tags: Am J Psychiatry Source Type: research

The "Loss of Pride" Syndrome in Yazidi Refugees.
The "Loss of Pride" Syndrome in Yazidi Refugees. Am J Psychiatry. 2018 Feb 01;175(2):112-113 Authors: Bou Khalil R, Guimaraes A, Richa S PMID: 29385826 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2018 Category: Psychiatry Authors: Bou Khalil R, Guimaraes A, Richa S Tags: Am J Psychiatry Source Type: research

Pharmacogenetic Tests in Psychiatry.
PMID: 29385827 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2018 Category: Psychiatry Authors: Bousman C, Allen J, Eyre HA Tags: Am J Psychiatry Source Type: research

Prolonged Postconcussive Symptoms.
PMID: 29385828 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2018 Category: Psychiatry Authors: Quinn DK, Mayer AR, Master CL, Fann JR Tags: Am J Psychiatry Source Type: research

Growing Up: Evolving Concepts of Adult Attention Deficit Hyperactivity Disorder.
PMID: 29385829 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2018 Category: Psychiatry Authors: Shaw P Tags: Am J Psychiatry Source Type: research

Antisuicidal Effects of Ketamine: A Promising First Step.
PMID: 29385830 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2018 Category: Psychiatry Authors: Trivedi MH Tags: Am J Psychiatry Source Type: research

The Importance of Adequately Powered Clinical Studies: Response to Khan et al.
PMID: 29385831 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2018 Category: Psychiatry Authors: Marder SR, Laughren T, Romano SJ Tags: Am J Psychiatry Source Type: research

Public Health Perspectives on Depressive Disordersedited by Neal L. Cohen, M.D. Baltimore, Johns Hopkins University Press, 2017, 456 pp., $49.95 (paperback).
PMID: 29385832 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2018 Category: Psychiatry Authors: Conway CR Tags: Am J Psychiatry Source Type: research

Why Apathy in Alzheimer's Matters.
PMID: 29385833 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - February 1, 2018 Category: Psychiatry Authors: Sultzer DL Tags: Am J Psychiatry Source Type: research

Care Pathways Before First Diagnosis of a Psychotic Disorder in Adolescents and Young Adults.
CONCLUSIONS: Most patients receiving a first diagnosis of a psychotic disorder had some indication of mental health care need during the previous year. General use of primary care or mental health services, however, does not clearly distinguish people who later receive a diagnosis of a psychotic disorder from those who later receive a diagnosis of unipolar depression. Use of inpatient or emergency department mental health care is a more specific indicator of risk. PMID: 29361848 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - January 24, 2018 Category: Psychiatry Authors: Simon GE, Stewart C, Hunkeler EM, Yarborough BJ, Lynch F, Coleman KJ, Beck A, Operskalski BH, Penfold RB, Carrell DS Tags: Am J Psychiatry Source Type: research

Role of Complex Epigenetic Switching in Tumor Necrosis Factor- α Upregulation in the Prefrontal Cortex of Suicide Subjects.
CONCLUSIONS: The data in this study provide mechanistic insights into the dysregulation of the TNF-α gene in the brains of individuals who died by suicide, which could potentially be involved in suicidal behavior. PMID: 29361849 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - January 24, 2018 Category: Psychiatry Authors: Wang Q, Roy B, Turecki G, Shelton RC, Dwivedi Y Tags: Am J Psychiatry Source Type: research

Early Intervention in Bipolar Disorder.
Abstract Bipolar disorder is a recurrent disorder that affects more than 1% of the world population and usually has its onset during youth. Its chronic course is associated with high rates of morbidity and mortality, making bipolar disorder one of the main causes of disability among young and working-age people. The implementation of early intervention strategies may help to change the outcome of the illness and avert potentially irreversible harm to patients with bipolar disorder, as early phases may be more responsive to treatment and may need less aggressive therapies. Early intervention in bipolar disorder is ...
Source: The American Journal of Psychiatry - January 24, 2018 Category: Psychiatry Authors: Vieta E, Salagre E, Grande I, Carvalho AF, Fernandes BS, Berk M, Birmaher B, Tohen M, Suppes T Tags: Am J Psychiatry Source Type: research

Reduction of PTSD Symptoms With Pre-Reactivation Propranolol Therapy: A Randomized Controlled Trial.
CONCLUSIONS: Pre-reactivation propranolol, a treatment protocol suggested by reconsolidation theory, appears to be a novel and efficacious treatment for PTSD. Replication studies using a long-term follow-up in various trauma populations are required. PMID: 29325446 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - January 12, 2018 Category: Psychiatry Authors: Brunet A, Saumier D, Liu A, Streiner DL, Tremblay J, Pitman RK Tags: Am J Psychiatry Source Type: research

Longitudinal Association of Amyloid Beta and Anxious-Depressive Symptoms in Cognitively Normal Older Adults.
CONCLUSIONS: Higher amyloid beta burden was associated with increasing anxious-depressive symptoms over time in cognitively normal older individuals. Prior depression history was related to higher but not worsening symptom ratings. These results suggest a direct or indirect association of elevated amyloid beta levels with worsening anxious-depressive symptoms and support the hypothesis that emerging neuropsychiatric symptoms represent an early manifestation of preclinical Alzheimer's disease. PMID: 29325447 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - January 12, 2018 Category: Psychiatry Authors: Donovan NJ, Locascio JJ, Marshall GA, Gatchel J, Hanseeuw BJ, Rentz DM, Johnson KA, Sperling RA, Harvard Aging Brain Study Tags: Am J Psychiatry Source Type: research

Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients.
CONCLUSIONS: The CYP2C19 genotype had a substantial impact on exposure and therapeutic failure of escitalopram, as measured by switching of antidepressant therapy. The results support the potential clinical utility of CYP2C19 genotyping for individualization of escitalopram therapy. PMID: 29325448 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - January 12, 2018 Category: Psychiatry Authors: Jukić MM, Haslemo T, Molden E, Ingelman-Sundberg M Tags: Am J Psychiatry Source Type: research

Analysis of DNA Methylation in Young People: Limited Evidence for an Association Between Victimization Stress and Epigenetic Variation in Blood.
CONCLUSIONS: Findings from this epidemiological analysis of the epigenetic effects of early-life stress do not support the hypothesis of robust changes in DNA methylation in victimized young people. We need to come to terms with the possibility that epigenetic epidemiology is not yet well matched to experimental, nonhuman models in uncovering the biological embedding of stress. PMID: 29325449 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - January 12, 2018 Category: Psychiatry Authors: Marzi SJ, Sugden K, Arseneault L, Belsky DW, Burrage J, Corcoran DL, Danese A, Fisher HL, Hannon E, Moffitt TE, Odgers CL, Pariante C, Poulton R, Williams BS, Wong CCY, Mill J, Caspi A Tags: Am J Psychiatry Source Type: research

The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder.
PMID: 29301420 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - January 1, 2018 Category: Psychiatry Authors: Reus VI, Fochtmann LJ, Bukstein O, Eyler AE, Hilty DM, Horvitz-Lennon M, Mahoney J, Pasic J, Weaver M, Wills CD, McIntyre J, Kidd J, Yager J, Hong SH Tags: Am J Psychiatry Source Type: research

AJP at 175: Remembering Our Past as We Envision Our Future.
PMID: 29301421 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - January 1, 2018 Category: Psychiatry Authors: Freedman R Tags: Am J Psychiatry Source Type: research