A Farewell.
PMID: 30501411 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2018 Category: Psychiatry Authors: Freedman R Tags: Am J Psychiatry Source Type: research

Accurate Assessment of Risk of Major Malformations in Infants With First-Trimester Exposure to Quetiapine.
PMID: 30501412 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2018 Category: Psychiatry Authors: Spinelli MG Tags: Am J Psychiatry Source Type: research

The Influence of Unmeasured Confounding Effects in a Study of Antipsychotic Discontinuation in First-Episode Schizophrenia.
PMID: 30501413 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2018 Category: Psychiatry Authors: Ghosh A, Noble D Tags: Am J Psychiatry Source Type: research

Prazosin for the Treatment of Alcohol Use Disorders.
PMID: 30501414 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2018 Category: Psychiatry Authors: Sinha R Tags: Am J Psychiatry Source Type: research

2018 in Review.
PMID: 30501415 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2018 Category: Psychiatry Authors: Freedman R, Lewis DA, Michels R, Pine DS, Rush AJ, Schultz SK, Tamminga CA, Glass O Tags: Am J Psychiatry Source Type: research

Perspectives on the Management of Vascular Depression.
PMID: 30501416 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2018 Category: Psychiatry Authors: Taylor WD, Schultz SK, Panaite V, Steffens DC Tags: Am J Psychiatry Source Type: research

No Effect of Lamotrigine in Subgroups of Patients With Borderline Personality Disorder: Response to Smith.
PMID: 30501417 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2018 Category: Psychiatry Authors: Crawford MJ, Sanatinia R, Tan W Tags: Am J Psychiatry Source Type: research

T.R. Beck (1791-1855).
PMID: 30501418 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2018 Category: Psychiatry Authors: Haldipur CV Tags: Am J Psychiatry Source Type: research

An Opportunity to Report Closer-to-Efficacy Findings in a Study of Lamotrigine for Borderline Personality Disorder.
PMID: 30501419 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2018 Category: Psychiatry Authors: Smith EG Tags: Am J Psychiatry Source Type: research

When Discontinuing SSRI Antidepressants Is a Challenge: Management Tips.
PMID: 30501420 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2018 Category: Psychiatry Authors: Jha MK, Rush AJ, Trivedi MH Tags: Am J Psychiatry Source Type: research

Risk of Treatment Failure: Response to Ghosh and Noble.
PMID: 30501421 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - December 1, 2018 Category: Psychiatry Authors: Tiihonen J, Tanskanen A, Taipale H Tags: Am J Psychiatry Source Type: research

Protective Effects of Pregnancy on Risk of Alcohol Use Disorder.
CONCLUSIONS:: The findings suggest that pregnancy plays a critical, and likely causal, motivational role in reducing alcohol use disorder risk among women and, to a lesser extent, their partners. These results extend our understanding of the relationship between pregnancy and alcohol use, demonstrating that even a severe condition such as alcohol use disorder is subject to the protective effects of pregnancy. PMID: 30486670 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 29, 2018 Category: Psychiatry Authors: Edwards AC, Ohlsson H, Svikis DS, Sundquist J, Sundquist K, Kendler KS Tags: Am J Psychiatry Source Type: research

Developmental Contributions of Schizophrenia Risk Alleles and Childhood Peer Victimization to Early-Onset Mental Health Trajectories.
CONCLUSIONS:: While the early development of emotional problems was associated with genetic risk (schizophrenia risk alleles), the subsequent course of emotional problems for those who might otherwise have remained on a more favorable trajectory was altered by exposure to peer victimization, which is a potentially modifiable environmental exposure. PMID: 30486671 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 29, 2018 Category: Psychiatry Authors: Riglin L, Hammerton G, Heron J, Collishaw S, Arseneault L, Thapar AK, Maughan B, O'Donovan MC, Thapar A Tags: Am J Psychiatry Source Type: research

Schizophrenia Polygenic Risk Score as a Predictor of Antipsychotic Efficacy in First-Episode Psychosis.
Abstract OBJECTIVE:: Pharmacogenomic studies of antipsychotics have typically examined effects of individual polymorphisms. By contrast, polygenic risk scores (PRSs) derived from genome-wide association studies (GWAS) can quantify the influence of thousands of common alleles of small effect in a single measure. The authors examined whether PRSs for schizophrenia were predictive of antipsychotic efficacy in four independent cohorts of patients with first-episode psychosis (total N=510). METHOD:: All study subjects received initial treatment with antipsychotic medication for first-episode psychosis, and all wer...
Source: The American Journal of Psychiatry - November 5, 2018 Category: Psychiatry Authors: Zhang JP, Robinson D, Yu J, Gallego J, Fleischhacker WW, Kahn RS, Crespo-Facorro B, Vazquez-Bourgon J, Kane JM, Malhotra AK, Lencz T Tags: Am J Psychiatry Source Type: research

Joint Contributions of Rare Copy Number Variants and Common SNPs to Risk for Schizophrenia.
CONCLUSIONS:: The authors found evidence for interactive effects of PRS and previously associated CNVs for risk for schizophrenia, and the results for large deletions and total CNV burden support an additive model. These findings offer insights into the genetic architecture of schizophrenia by illuminating how different established genetic risk factors act and interact to influence liability to schizophrenia. PMID: 30392412 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 5, 2018 Category: Psychiatry Authors: Bergen SE, Ploner A, Howrigan D, CNV Analysis Group and the Schizophrenia Working Group of the Psychiatric Genomics Consortium, O'Donovan MC, Smoller JW, Sullivan PF, Sebat J, Neale B, Kendler KS Tags: Am J Psychiatry Source Type: research

A Transgender Woman With Intellectual Disability and Borderline Personality Disorder.
PMID: 30380931 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2018 Category: Psychiatry Authors: Newman WJ, Barnhorst AV, Landess JS Tags: Am J Psychiatry Source Type: research

Developmental Window of Opportunity: Implications of Parent-Child Psychotherapy for Early Childhood Depression Treatment.
PMID: 30380932 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2018 Category: Psychiatry Authors: Silverman WK, Pettit JW Tags: Am J Psychiatry Source Type: research

Reconsolidation of Traumatic Memories Using Psychotherapy.
PMID: 30380933 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2018 Category: Psychiatry Authors: Waits WM, Hoge CW Tags: Am J Psychiatry Source Type: research

Treating Victims of Child Sexual Abuse.
PMID: 30380934 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2018 Category: Psychiatry Authors: Hanson RF, Wallis E Tags: Am J Psychiatry Source Type: research

Therapeutic Effects of the Traditional "Doing the Month" Practices on Postpartum Depression in China.
Therapeutic Effects of the Traditional "Doing the Month" Practices on Postpartum Depression in China. Am J Psychiatry. 2018 Nov 01;175(11):1071-1072 Authors: Ding G, Yu J, Vinturache A, Gu H, Lu M PMID: 30380935 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2018 Category: Psychiatry Authors: Ding G, Yu J, Vinturache A, Gu H, Lu M Tags: Am J Psychiatry Source Type: research

Population-Based Estimates of Heritability Shed New Light on Clinical Features of Major Depression.
PMID: 30380936 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2018 Category: Psychiatry Authors: McMahon FJ Tags: Am J Psychiatry Source Type: research

On the Use of Memory Update Mechanisms to Treat Patients: Response to Waits and Hoge.
PMID: 30380937 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2018 Category: Psychiatry Authors: Brunet A, Saumier D, Pitman RK Tags: Am J Psychiatry Source Type: research

Antipsychotics and Their Impact on Cerebral White Matter: Part of the Problem or Part of the Solution?
PMID: 30380938 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2018 Category: Psychiatry Authors: Kubicki M, Lyall AE Tags: Am J Psychiatry Source Type: research

Cigarette Smoking, Cognitive Performance, and Severe Mental Illness: Quitting Smoking Really Does Seem to Matter.
PMID: 30380939 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - November 1, 2018 Category: Psychiatry Authors: Harvey PD Tags: Am J Psychiatry Source Type: research

Genome-Wide Association Study Meta-Analysis of the Alcohol Use Disorders Identification Test (AUDIT) in Two Population-Based Cohorts.
CONCLUSIONS:: AUDIT scores ascertained in population-based cohorts can be used to explore the genetic basis of both alcohol consumption and alcohol use disorders. PMID: 30336701 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 19, 2018 Category: Psychiatry Authors: Sanchez-Roige S, Palmer AA, Fontanillas P, Elson SL, 23andMe Research Team, Substance Use Disorder Working Group of the Psychiatric Genomics Consortium, Adams MJ, Howard DM, Edenberg HJ, Davies G, Crist RC, Deary IJ, McIntosh AM, Clarke TK Tags: Am J Psychiatry Source Type: research

Doubly Randomized Preference Trial of Prolonged Exposure Versus Sertraline for Treatment of PTSD.
CONCLUSIONS:: Prolonged exposure and sertraline confer significant benefits for PTSD, with some evidence of an advantage for prolonged exposure. Giving patients with PTSD their preferred treatment also confers important benefits, including enhancing adherence. PMID: 30336702 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 19, 2018 Category: Psychiatry Authors: Zoellner LA, Roy-Byrne PP, Mavissakalian M, Feeny NC Tags: Am J Psychiatry Source Type: research

A Randomized Trial Comparing Extended-Release Injectable Suspension and Oral Naltrexone, Both Combined With Behavioral Therapy, for the Treatment of Opioid Use Disorder.
CONCLUSIONS:: Patients receiving XR-naltrexone had twice the rate of treatment retention at 6 months compared with those taking oral naltrexone. These results support the use of XR-naltrexone combined with behavioral therapy as an effective treatment for patients seeking opioid withdrawal and nonagonist treatment for preventing relapse to opioid use disorder. PMID: 30336703 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 19, 2018 Category: Psychiatry Authors: Sullivan MA, Bisaga A, Pavlicova M, Carpenter KM, Choi CJ, Mishlen K, Levin FR, Mariani JJ, Nunes EV Tags: Am J Psychiatry Source Type: research

Brain Mechanisms of Attention Orienting Following Frustration: Associations With Irritability and Age in Youths.
CONCLUSIONS:: Following frustration, levels of irritability correlated with activity in neural systems mediating attention orienting, top-down regulation of emotions, and motor execution. Although most associations were independent of age, dysfunction in the anterior cingulate cortex and posterior regions was more pronounced in young children with irritability. PMID: 30336704 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 19, 2018 Category: Psychiatry Authors: Tseng WL, Deveney CM, Stoddard J, Kircanski K, Frackman AE, Yi JY, Hsu D, Moroney E, Machlin L, Donahue L, Roule A, Perhamus G, Reynolds RC, Roberson-Nay R, Hettema JM, Towbin KE, Stringaris A, Pine DS, Brotman MA, Leibenluft E Tags: Am J Psychiatry Source Type: research

Mega-Analysis of Gray Matter Volume in Substance Dependence: General and Substance-Specific Regional Effects.
CONCLUSIONS:: The results indicate that dependence on a range of different substances shares a common neural substrate and that differential patterns of regional volume could serve as useful biomarkers of dependence on alcohol and nicotine. PMID: 30336705 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 19, 2018 Category: Psychiatry Authors: Mackey S, Allgaier N, Chaarani B, Spechler P, Orr C, Bunn J, Allen NB, Alia-Klein N, Batalla A, Blaine S, Brooks S, Caparelli E, Chye YY, Cousijn J, Dagher A, Desrivieres S, Feldstein-Ewing S, Foxe JJ, Goldstein RZ, Goudriaan AE, Heitzeg MM, Hester R, Hut Tags: Am J Psychiatry Source Type: research

Electroencephalographic Biomarkers for Treatment Response Prediction in Major Depressive Illness: A Meta-Analysis.
CONCLUSIONS:: QEEG does not appear to be clinically reliable for predicting depression treatment response, as the literature is limited by underreporting of negative results, a lack of out-of-sample validation, and insufficient direct replication of previous findings. Until these limitations are remedied, QEEG is not recommended for guiding selection of psychiatric treatment. PMID: 30278789 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 3, 2018 Category: Psychiatry Authors: Widge AS, Bilge MT, Montana R, Chang W, Rodriguez CI, Deckersbach T, Carpenter LL, Kalin NH, Nemeroff CB Tags: Am J Psychiatry Source Type: research

A Population-Based Analysis of the Relationship Between Substance Use and Adolescent Cognitive Development.
CONCLUSIONS:: Beyond the role of cognition in vulnerability to substance use, the concurrent and lasting effects of adolescent cannabis use can be observed on important cognitive functions and appear to be more pronounced than those observed for alcohol. PMID: 30278790 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 3, 2018 Category: Psychiatry Authors: Morin JG, Afzali MH, Bourque J, Stewart SH, Séguin JR, O'Leary-Barrett M, Conrod PJ Tags: Am J Psychiatry Source Type: research

Impaired Motion Processing in Schizophrenia and the Attenuated Psychosis Syndrome: Etiological and Clinical Implications.
CONCLUSIONS:: The study findings emphasize the importance of sensory-level visual dysfunction in the etiology of schizophrenia and in the personal experience of individuals with the disorder and demonstrate that motion-processing deficits may predate illness onset and contribute to impaired function even in patients with attenuated psychosis. PMID: 30278791 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 3, 2018 Category: Psychiatry Authors: Martínez A, Gaspar PA, Hillyard SA, Andersen SK, Lopez-Calderon J, Corcoran CM, Javitt DC Tags: Am J Psychiatry Source Type: research

Intellectual Disability and Psychotic Disorders in Children: Association With Maternal Severe Mental Illness and Exposure to Obstetric Complications in a Whole-Population Cohort.
CONCLUSIONS:: Maternal severe mental illness and exposure to obstetric complications contribute separately to the risk of intellectual disability, suggesting potentially different causal pathways. PMID: 30278792 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 3, 2018 Category: Psychiatry Authors: Di Prinzio P, M.Biostat., Morgan VA, M.Soc.Sc., Björk J, Croft M, Lin A, Jablensky A, McNeil TF Tags: Am J Psychiatry Source Type: research

Alleviating the Mental Health Burden of Structural Discrimination and Hate Crimes: The Role of Psychiatrists.
PMID: 30269535 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Authors: Hansen H, Riano NS, Meadows T, Mangurian C Tags: Am J Psychiatry Source Type: research

Anticipating Suicide Will Be Hard, But This Is Progress.
PMID: 30269536 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Authors: Chekroud AM Tags: Am J Psychiatry Source Type: research

Dire Need for New and Improved Therapies for PTSD: Response to Markowitz.
PMID: 30269537 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Authors: Stein MB, Rothbaum BO Tags: Am J Psychiatry Source Type: research

Foundations of Consultation-Liaison Psychiatry.
PMID: 30269539 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Authors: Taylor GJ Tags: Am J Psychiatry Source Type: research

APA Council Reports.
Authors: PMID: 30269540 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Tags: Am J Psychiatry Source Type: research

Interrupted Meal, by Heinrich von Rustige.
PMID: 30269541 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Authors: Cambioli L, Riva MA Tags: Am J Psychiatry Source Type: research

Assessment and Treatment of Gender Dysphoria and Gender Variant Patients: A Primer for Psychiatrists.
PMID: 30269542 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Authors: Byne W, Karasic DH, Coleman E, Eyler AE, Kidd JD, Meyer-Bahlburg HFL, Pleak RR, Pula J Tags: Am J Psychiatry Source Type: research

The Range of Psychotherapies for PTSD.
PMID: 30269543 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Authors: Markowitz JC Tags: Am J Psychiatry Source Type: research

Insight Into Insight in Psychotherapy.
end P PMID: 30269544 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Authors: Høglend P Tags: Am J Psychiatry Source Type: research

Evidence Over Dogma: Embracing an Expanding Repertoire of PTSD Treatment Options.
PMID: 30269545 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Authors: Aupperle RL Tags: Am J Psychiatry Source Type: research

Microscopes and Telescopes: the Societal Impact of Substance Use Disorder Treatment.
PMID: 30269546 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Authors: Connery HS, Weiss RD Tags: Am J Psychiatry Source Type: research

Progress in PTSD.
PMID: 30269547 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - October 1, 2018 Category: Psychiatry Authors: Eth S Tags: Am J Psychiatry Source Type: research

Improving Depression Outcome by Patient-Centered Medical Management.
Abstract Specific challenges that profoundly affect the outcome of treatment for depression include 1) patient engagement and retention in care and optimization of treatment adherence, 2) optimization of symptom and side effect control by medication adjustments using measurement-based care procedures, 3) restoration of daily functioning and quality of life, and 4) prevention or at least mitigation of symptomatic relapse or recurrence. According to data from the Sequenced Treatment Alternatives to Relieve Depression study, some 10%-15% of patients will not return for treatment after an initial thorough evaluation v...
Source: The American Journal of Psychiatry - September 17, 2018 Category: Psychiatry Authors: Rush AJ, Thase ME Tags: Am J Psychiatry Source Type: research

Multimodal Structural Neuroimaging Markers of Brain Development and ADHD Symptoms.
CONCLUSIONS: The findings suggest that ADHD presentation may arise from a summation of several clinical, developmental, or cognitive factors, each with a distinct neuroanatomical foundation. This informs the neurobiological foundations of ADHD and highlights the value of detailed phenotypic data in understanding the neurobiology underlying neurodevelopmental disorders. PMID: 30220220 [PubMed - as supplied by publisher] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - September 17, 2018 Category: Psychiatry Authors: Ball G, Malpas CB, Genc S, Efron D, Sciberras E, Anderson V, Nicholson JM, Silk TJ Tags: Am J Psychiatry Source Type: research

Maternal Immune Activation and Neuropsychiatric Illness: A Translational Research Perspective.
Abstract Epidemiologic studies, including prospective birth cohort investigations, have implicated maternal immune activation in the etiology of neuropsychiatric disorders. Maternal infectious pathogens and inflammation are plausible risk factors for these outcomes and have been associated with schizophrenia, autism spectrum disorder, and bipolar disorder. Concurrent with epidemiologic research are animal models of prenatal immune activation, which have documented behavioral, neurochemical, neuroanatomic, and neurophysiologic disruptions that mirror phenotypes observed in these neuropsychiatric disorders. Epidemio...
Source: The American Journal of Psychiatry - September 17, 2018 Category: Psychiatry Authors: Brown AS, Meyer U Tags: Am J Psychiatry Source Type: research

Is Euthanasia Psychiatric Treatment? The Struggle With Death on Request in the Netherlands.
PMID: 30173544 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - September 1, 2018 Category: Psychiatry Authors: Denys D Tags: Am J Psychiatry Source Type: research

Validating the Predictive Accuracy of the NAPLS-2 Psychosis Risk Calculator in a Clinical High-Risk Sample From the SHARP (Shanghai At Risk for Psychosis) Program.
PMID: 30173545 [PubMed - in process] (Source: The American Journal of Psychiatry)
Source: The American Journal of Psychiatry - September 1, 2018 Category: Psychiatry Authors: Zhang T, Li H, Tang Y, Niznikiewicz MA, Shenton ME, Keshavan MS, Stone WS, McCarley RW, Seidman LJ, Wang J Tags: Am J Psychiatry Source Type: research