Breast Cancer Screening, Management, and a Review of Case Study Literature in Transgender Populations
This article describes existing evidence on breast cancer incidence in transgender women and men, and attempts to make rational recommendations regarding the screening for and approach to managing breast cancer in transgender populations. Current data are mostly limited to case reports which are reviewed here. More prospective, population-level research is needed to better understand the risks and predictors of breast cancer in this population, as well as to better inform the most appropriate screening modality, age of starting screening, and interval. Ultimately, a risk score calculator similar to existing risk models suc...
Source: Seminars in Reproductive Medicine - October 26, 2017 Category: Reproduction Medicine Authors: Deutsch, Madeline B. Radix, Asa Wesp, Linda Tags: Review Article Source Type: research
Preventive Health for Transgender Men and Women
Semin Reprod Med 2017; 35: 426-433 DOI: 10.1055/s-0037-1604457Transgender men and women experience an incongruity between their assigned sex at birth and their identified gender. Gender dysphoria is defined by the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5) as clinically significant distress or impairment resulting from misalignment in assigned and experienced gender. Transgender people have a history of negative experiences in health care and efforts should be made to create a welcoming environment through staff training, gender neutral restrooms, and gender inclusive electronic medical reco...
Source: Seminars in Reproductive Medicine - October 26, 2017 Category: Reproduction Medicine Authors: Imborek, Katherine L. Graf, Elizabeth M. McCune, Kaitlyn Tags: Review Article Source Type: research
Lesbian Pregnancy: Care and Considerations
Semin Reprod Med 2017; 35: 420-425 DOI: 10.1055/s-0037-1606385The constructs and the provision of preconception and obstetrical care have historically been based on the assumption of heterosexuality, and have often excluded lesbian women. However, due to significant strides in lesbian, gay, bisexual, transgender, and queer (LGBTQ) civil rights, more lesbian women desire to create and expand their families, and lesbian parented families are increasing. This places obstetrical care providers at the forefront of the movement to build inclusive health care environments. Therefore, it is incumbent upon those of us who work in o...
Source: Seminars in Reproductive Medicine - October 26, 2017 Category: Reproduction Medicine Authors: Bushe, Sierra Romero, Iris L. Tags: Review Article Source Type: research
Co-IVF for Same-Sex Female Couples
Semin Reprod Med 2017; 35: 415-419 DOI: 10.1055/s-0037-1605380The utilization of assisted reproductive technology (ART), particularly by same-sex female couples (SSFCs), has increased over the past few decades. Alongside the increase in use by lesbian women, there has also been an increase in the number of available treatment options. The process by which SSFCs make the various decisions associated with conceiving and parenting, however, has been largely overlooked. This review provides an overview of the reproductive treatments available to lesbian women and specifically highlights the “biological” and “social” ob...
Source: Seminars in Reproductive Medicine - October 26, 2017 Category: Reproduction Medicine Authors: Getrajdman, Chloe Lee, Joseph A. Copperman, Alan B. Tags: Review Article Source Type: research
Family Building by Same-Sex Male Couples via Gestational Surrogacy
This article will review the FDA regulations and ASRM recommendations and their implications for same-sex male couples who plan to conceive via gestational surrogacy. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Abstract | Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - October 26, 2017 Category: Reproduction Medicine Authors: Kim, Helen H. Tags: Review Article Source Type: research
Establishing Effective Health Care Partnerships with Sexual and Gender Minority Patients: Recommendations for Obstetrician Gynecologists
This article documents multiple suggestions and resources that health care teams can use to improve the health and health care of their sexual and gender minority patients. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Abstract | Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - October 26, 2017 Category: Reproduction Medicine Authors: Cook, Scott C. Gunter, Kathryn E. Lopez, Fanny Y. Tags: Review Article Source Type: research
Obstetrics and Gynecology: A Specialty at the Forefront of Care for LGBTQ Patients
Semin Reprod Med 2017; 35: 395-396 DOI: 10.1055/s-0037-1607044 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - October 26, 2017 Category: Reproduction Medicine Authors: Romero, Iris L. Tags: Preface Source Type: research
Iris L. Romero, MD, MS
Semin Reprod Med 2017; 35: 393-394 DOI: 10.1055/s-0037-1607361 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - October 26, 2017 Category: Reproduction Medicine Authors: Legro, Richard S. Tags: Introduction Source Type: research
Perinatal and Childhood Outcomes Associated with Infertility
Semin Reprod Med 2017; 35: 304-310 DOI: 10.1055/s-0037-1603584Infertility affects 11% of reproductive-age women in the United States and the number of live births from infertility treatment, both in vitro fertilization (IVF) and non-IVF fertility treatment (NIFT), continues to rise. Given this trend, the perinatal and childhood outcomes of children conceived with assisted reproduction are of critical importance. We provide a comprehensive overview of the current literature, consisting primarily of observational cohort studies focused on IVF children. The outcomes of interest include (1) perinatal outcomes of low birth weig...
Source: Seminars in Reproductive Medicine - June 28, 2017 Category: Reproduction Medicine Authors: Zore, Temeka Wang, Erica T. Tags: Review Article Source Type: research
Male Infertility and Risk of Cancer
Semin Reprod Med 2017; 35: 298-303 DOI: 10.1055/s-0037-1603583Male infertility is a complex and incompletely understood process that is thought to affect around 10% of the male population. Infertility is a complex interaction between genetics and environmental factors, which is increasingly being recognized as a potential marker of contemporary or future medical disease, including cancer. The best characterized association between infertility and cancer risk is that of testicular germ cell tumor, but increased risk for prostate cancer, melanoma, non-Hodgkin's lymphoma, and others have also been described. Much like inferti...
Source: Seminars in Reproductive Medicine - June 28, 2017 Category: Reproduction Medicine Authors: Rogers, Marc J. Walsh, Thomas J. Tags: Review Article Source Type: research
Fertility Status and Cancer
Semin Reprod Med 2017; 35: 291-297 DOI: 10.1055/s-0037-1603098Elevated estradiol levels associated with ovulation-stimulating drugs used to treat infertility and ovarian punctures involved with in vitro fertilization (IVF) have led to concerns regarding long-term cancer effects. Assessed risks, however, have been contradictory. This may reflect small sample sizes and short follow-up times, as well as an inability of many studies to adjust for appropriate potential confounders, such as causes of infertility and parity. While early studies of ovulation-stimulating drugs suggested large increases in large ovarian cancer risk,...
Source: Seminars in Reproductive Medicine - June 28, 2017 Category: Reproduction Medicine Authors: Brinton, Louise A. Tags: Review Article Source Type: research
Male Infertility and Risk of Nonmalignant Chronic Diseases: A Systematic Review of the Epidemiological Evidence
Semin Reprod Med 2017; 35: 282-290 DOI: 10.1055/s-0037-1603568The association between male infertility and increased risk of certain cancers is well studied. Less is known about the long-term risk of nonmalignant diseases in men with decreased fertility. A systemic literature review was performed on the epidemiologic evidence of male infertility as a precursor for increased risk of diabetes, cardiovascular diseases, and all-cause mortality. PubMed and Embase were searched from January 1, 1980, to September 1, 2016, to identify epidemiological studies reporting associations between male infertility and the outcomes of inter...
Source: Seminars in Reproductive Medicine - June 28, 2017 Category: Reproduction Medicine Authors: Glazer, Clara Helene Bonde, Jens Peter Eisenberg, Michael L. Giwercman, Aleksander H ærvig, Katia Keglberg Rimborg, Susie Vassard, Ditte Pinborg, Anja Schmidt, Lone Br äuner, Elvira Vaclavik Tags: Review Article Source Type: research
Polycystic Ovarian Syndrome: Long-Term Health Consequences
In conclusion, strategies for the prevention and amelioration of long-term morbidities in PCOS are presented. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents | Abstract | Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - June 28, 2017 Category: Reproduction Medicine Authors: Zore, Temeka Joshi, Nikhil V. Lizneva, Daria Azziz, Ricardo Tags: Review Article Source Type: research
The Systemic Effects of Endometriosis
Semin Reprod Med 2017; 35: 263-270 DOI: 10.1055/s-0037-1603582Endometriosis is a condition defined by the presence of endometrial glands and stroma in ectopic locations. While the most commonly seen symptoms of the disease are pelvic pain, dysmenorrhea, and infertility, endometriosis has also systemic effects in multiple organ systems. Here, we review literature describing closely associated comorbidities including cardiovascular disease, cancers, autoimmune disease, psychiatric conditions, and metabolism/body weight. We examine the pathophysiology and hypothesized mechanism by which endometriosis may lead to these systemi...
Source: Seminars in Reproductive Medicine - June 28, 2017 Category: Reproduction Medicine Authors: Alderman, Myles H. Yoder, Nicole Taylor, Hugh S. Tags: Review Article Source Type: research
Hypothalamic Amenorrhea and the Long-Term Health Consequences
Semin Reprod Med 2017; 35: 256-262 DOI: 10.1055/s-0037-1603581The menstrual cycle is a reproductive vital sign and provides insight into hormonal imbalance as well as pregnancy. The significance of estrogen, however, extends beyond fertility and plays a role on tissues and organs throughout the body. Functional hypothalamic amenorrhea is a common form of secondary amenorrhea resulting in estrogen deficiency in young premenopausal women. While reversible, the cause of this disorder is related to psychological stress, excessive exercise, disordered eating, or a combination of these factors resulting in suppression of the hyp...
Source: Seminars in Reproductive Medicine - June 28, 2017 Category: Reproduction Medicine Authors: Shufelt, Chrisandra L. Torbati, Tina Dutra, Erika Tags: Review Article Source Type: research
