Child Health: Is It Really Assisted Reproductive Technology that We Need to Be Concerned About?
Semin Reprod Med 2018; 36: 183-194 DOI: 10.1055/s-0038-1675778Concerns remain about the health of children conceived by infertility treatment. Studies to date have predominantly not identified substantial long-term health effects after accounting for plurality, which is reassuring given the increasing numbers of children conceived by infertility treatment worldwide. However, as technological advances in treatment arise, ongoing studies remain critical for monitoring health effects. To study whether the techniques used in infertility treatment cause health differences, however, remains challenging due to identification of a...
Source: Seminars in Reproductive Medicine - March 12, 2019 Category: Reproduction Medicine Authors: Yeung, Edwina H. Kim, Keewan Purdue-Smithe, Alexandra Bell, Griffith Zolton, Jessica Ghassabian, Akhgar Vafai, Yassaman Robinson, Sonia L. Mumford, Sunni L. Tags: Review Article Source Type: research

Developmental Origins of Health and Disease: The History of the Barker Hypothesis and Assisted Reproductive Technology
Semin Reprod Med 2018; 36: 177-182 DOI: 10.1055/s-0038-1675779Since Barker's publication of “The fetal and infant origins of adult disease” in 1990, significant emphasis has been placed on the intrauterine environment and its effect on adult disease. Historical events such as the Dutch Famine and the 1918 Flu Pandemic have provided organic data about the epigenetic changes that can result from famine, infection, and stress. Mechanisms that allow for intrauterine survival may predispose to adult disease states when the fetus enters a world of abundance. As the field of in vitro fertilization (IVF) has developed and evol...
Source: Seminars in Reproductive Medicine - March 12, 2019 Category: Reproduction Medicine Authors: Carpinello, Olivia J. DeCherney, Alan H. Hill, Micah J. Tags: Review Article Source Type: research

Assisted Reproductive Technologies and the Developmental Origins of Human Health and Disease
Semin Reprod Med 2018; 36: 175-176 DOI: 10.1055/s-0039-1683393 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - March 12, 2019 Category: Reproduction Medicine Authors: Hill, Micah J. Tags: Preface Source Type: research

Assisted Reproductive Technologies and the Developmental Origins of Health and Disease
Semin Reprod Med 2018; 36: 173-174 DOI: 10.1055/s-0038-1676641 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - March 12, 2019 Category: Reproduction Medicine Authors: Segars, James H. Tags: Introduction Source Type: research

The Neuroanatomy of Reproduction: Seeing Is Believing
The objective of this pictorial tour is to elucidate anatomical and clinical relationships while showcasing the neuroanatomy of reproduction. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - January 3, 2019 Category: Reproduction Medicine Authors: Vlasak, Alexander L. Schaub, Amelia Barry, Margaret E. Robin Rhoton-Vlasak, Alice S. Tags: Review Article Source Type: research

Opioids and Alternatives in Female Chronic Pelvic Pain
This article reviews nonpharmacologic therapies including pelvic floor physical therapy, dietary modifications, psychotherapy, and acupuncture. These interventions are low risk and should be incorporated into treatment for chronic pelvic pain, as they show promise for successful symptom relief in many overlapping chronic pain conditions. Common nonopioid medications for pelvic are also reviewed, including analgesics, hormone modulating agents, antidepressants, and anticonvulsants. Guidelines for cautious and responsible opioid use are also summarized. While data specific to chronic pelvic pain management remain limited, ev...
Source: Seminars in Reproductive Medicine - December 19, 2018 Category: Reproduction Medicine Authors: Valentine, Lindsey N. Deimling, Timothy A. Tags: Review Article Source Type: research

Interventional Pain Management and Female Pelvic Pain: Considerations for Diagnosis and Treatment
Semin Reprod Med 2018; 36: 159-163 DOI: 10.1055/s-0038-1676104Chronic pelvic pain (CPP) is a recurring and/or constant pain of at least six months duration that has resulted in either functional or psychological disability that can require interventional treatments. Chronic pelvic pain can be visceral, somatic, neuropathic, or a combination. Patients with CPP often suffer from concurrent bowel or bladder dysfunction, sexual dysfunction, depression, and anxiety. The complexity of chronic pelvic pain can be challenging to treat, which can lead to frustration for both patients and their physicians. Treatment should involve a ...
Source: Seminars in Reproductive Medicine - December 19, 2018 Category: Reproduction Medicine Authors: Smith, Sadie E. Eckert, Jill M. Tags: Review Article Source Type: research

Female Sexual Dysfunction in Women with Pelvic Pain
This article provides a discussion of various conditions, offering diagnostic and therapeutic measures to consider in women with pelvic pain experiencing sexual dysfunction. Treatment and management options are also reviewed. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - December 19, 2018 Category: Reproduction Medicine Authors: Tam, Teresa Levine, Elliot M. Tags: Review Article Source Type: research

Endometriosis and Female Pelvic Pain
Semin Reprod Med 2018; 36: 143-151 DOI: 10.1055/s-0038-1676103Endometriosis is a nonmalignant gynecologic disorder that can have a significant impact on a woman's quality of life with pelvic pain and possible lasting effects on one's fertility. Symptoms, when present, can be severe and affect many organ systems including the gastrointestinal and urinary systems. Other etiologies of pelvic pain must be ruled out and/or need to be addressed concurrently for optimal patient care. There are numerous medical and surgical treatment options available that have been shown to be beneficial for endometriosis-related pelvic pain. Rec...
Source: Seminars in Reproductive Medicine - December 19, 2018 Category: Reproduction Medicine Authors: Kim, Jin Hee Han, Esther Tags: Review Article Source Type: research

Fibromyalgia and Irritable Bowel Syndrome in Female Pelvic Pain
Semin Reprod Med 2018; 36: 136-142 DOI: 10.1055/s-0038-1676090Fibromyalgia and irritable bowel syndrome are common disorders which often coexist in women with chronic pelvic pain. Like pelvic pain, these disorders describe symptoms without pathologic findings. Women with chronic pelvic pain have a higher prevalence of fibromyalgia (4–31%) and irritable bowel syndrome (8–41%) than the general population. Aberrant pain processing and psychosocial stressors are implicated in the co-occurrence of these pain syndromes (chronic overlapping pain conditions), but active epidemiologic, psychosocial, and neurobiologic research i...
Source: Seminars in Reproductive Medicine - December 19, 2018 Category: Reproduction Medicine Authors: Johnson, Christina M. Makai, Gretchen E. H. Tags: Review Article Source Type: research

Interstitial Cystitis/Bladder Pain Syndrome
Semin Reprod Med 2018; 36: 123-135 DOI: 10.1055/s-0038-1676089Interstitial cystitis/bladder pain syndrome is an uncommon but potentially devastating pelvic pain disorder affecting both women and men. This condition is often confusable and comorbid with other pelvic pain disorders. Although our understanding of the underlying pathophysiology is growing, the exact longitudinal course by which peripheral and central aberrations involving the bladder mucosa, peripheral inflammation, and central dysregulation of bladder sensitivity create painful bladder symptoms remains an area in need of further study. Only a limited number o...
Source: Seminars in Reproductive Medicine - December 19, 2018 Category: Reproduction Medicine Authors: Marcu, Ioana Campian, E. Cristian Tu, Frank F. Tags: Review Article Source Type: research

Pelvic Pain in Adolescents
Semin Reprod Med 2018; 36: 116-122 DOI: 10.1055/s-0038-1676088Dysmenorrhea and noncyclic pelvic pain (chronic pelvic pain) are common in adolescents. The evaluation of teens with dysmenorrhea or chronic pelvic pain is aimed to diagnose possible gynecologic conditions (endometriosis, pelvic inflammatory disease, ovarian cysts, and obstruction of the reproductive tract) and nongynecologic conditions (irritable bowel syndrome, interstitial cystitis, and myofascial pain). The management of chronic pelvic pain in adolescents is often more complex than in adult women because both the adolescent and her parents are counseled and ...
Source: Seminars in Reproductive Medicine - December 19, 2018 Category: Reproduction Medicine Authors: Smorgick, Noam As-Sanie, Sawsan Tags: Review Article Source Type: research

Musculoskeletal Considerations in Female Patients with Chronic Pelvic Pain
This article provides an overview of the pathophysiology of persistent pelvic pain, as it relates to musculoskeletal disorders. The symptomatology, anatomy, evaluation, and treatment of these disorders are summarized specifically for healthcare providers (including gynecologists) who do not have pelvic musculoskeletal expertise. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - December 19, 2018 Category: Reproduction Medicine Authors: Lamvu, Georgine Carrillo, Jorge Witzeman, Kathryn Alappattu, Meryl Tags: Review Article Source Type: research

Evaluation of Female Pelvic Pain
Semin Reprod Med 2018; 36: 099-106 DOI: 10.1055/s-0038-1676084Chronic pelvic pain is a condition defined by pelvic pain for more than six months which is severe enough to cause functional disability or require treatment. When pain becomes a chronic condition, it is more challenging to evaluate and treat. Chronic pelvic pain patients often have multiple factors contributing to their pain. Here, we review the approach to the evaluation of chronic female pelvic pain. It is important to establish a trusting patient–physician relationship. When evaluating a female patient with chronic pelvic pain, an in-depth history and targ...
Source: Seminars in Reproductive Medicine - December 19, 2018 Category: Reproduction Medicine Authors: Chandler, Jessica Wagner, Elena Riley, Kristin Tags: Review Article Source Type: research

Female Pelvic Pain
Semin Reprod Med 2018; 36: 097-098 DOI: 10.1055/s-0038-1676086 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - December 19, 2018 Category: Reproduction Medicine Authors: Harkins, Gerald J. Tags: Preface Source Type: research