Gerald J. Harkins, MD, MPT, FACOG
Semin Reprod Med 2018; 36: 095-096 DOI: 10.1055/s-0038-1676367 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - December 19, 2018 Category: Reproduction Medicine Authors: Legro, Richard S. Tags: Introduction Source Type: research

Integrated Model of Care for Polycystic Ovary Syndrome
Semin Reprod Med 2018; 36: 086-094 DOI: 10.1055/s-0038-1667310Polycystic ovary syndrome (PCOS) affects approximately one in seven women worldwide from early adulthood with heterogeneity in their healthcare needs through the life cycle. PCOS is challenging to diagnose and manage, with one-third of women reporting at least a 2-year delay in diagnosis. Current clinical services do not satisfactorily educate and support women with their diverse reproductive, metabolic, and psychological care needs with fragmentation of services across health providers. Women are dissatisfied with the care they received, while the first contact...
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Tay, Chau T. Moran, Lisa J. Wijeyaratne, Chandrika N. Redman, Leanne M. Norman, Robert J. Teede, Helena J. Joham, Anju E. Tags: Review Article Source Type: research

Informing Translation: The Accuracy of Information on Websites for Lifestyle Management of Polycystic Ovary Syndrome
Semin Reprod Med 2018; 36: 080-085 DOI: 10.1055/s-0038-1667309Lifestyle (diet, physical activity [PA], and/or behavioral) interventions are recommended for all women with polycystic ovary syndrome (PCOS) in international guidelines. The internet is a widely used health information resource. However, the accuracy of lifestyle information on PCOS websites is unknown and is reviewed here to inform translation of the international guideline on PCOS. An internet search was conducted with three search engines across different web browsers and countries. Accuracy was assessed through a checklist of 29 questions based on internati...
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Htet, Thaw Cassar, S. Boyle, Jacqueline A. Kuczynska-Burggraf, Millicent Gibson-Helm, Melanie Chiu, Wei-Ling Stepto, N. K. Moran, Lisa J. Tags: Review Article Source Type: research

A Governance Model Addressing the Challenges of Contemporary Research
Semin Reprod Med 2018; 36: 073-079 DOI: 10.1055/s-0038-1667157In this paper, we describe the robust governance structures and processes underpinning the development of the first International Evidence-Based Guideline for the Assessment and Management Polycystic Ovary Syndrome (2018). The guideline was an outcome of the Centre of Research Excellence for Polycystic Ovary Syndrome, and an example of a transformative, strategic research initiative to impact delivery model. The governance structure supported and delivered critical ethical and regulatory outcomes, including: broad and diverse representation across health profess...
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Downes, Linda Garad, Rhonda Teede, Helena J. Norman, Robert J. Tags: Review Article Source Type: research

Personalized Mobile Tool AskPCOS Delivering Evidence-Based Quality Information about Polycystic Ovary Syndrome
Semin Reprod Med 2018; 36: 066-072 DOI: 10.1055/s-0038-1667156Despite polycystic ovary syndrome (PCOS) being the most common endocrine condition affecting reproductive-aged women, studies have shown the information needs of PCOS consumers are not currently met. The expressed need by women with PCOS for accessible, evidence-based personalized PCOS information informed the design and development of the PCOS mobile tool—AskPCOS. The App provides a range of unique features such as: evidence-based PCOS health information, self-diagnostic function, a question prompt list to optimize health practitioner engagement, and a common...
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Xie, Jue Burstein, Frada Garad, Rhonda Teede, Helena J. Boyle, Jacqueline A. Tags: Review Article Source Type: research

Ask PCOS: Identifying Need to Inform Evidence-Based App Development for Polycystic Ovary Syndrome
Conclusion Women with PCOS would use a PCOS-specific app of good quality that responds to their needs and facilitates self-care; however, currently available apps are unlikely to meet their information needs. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Boyle, Jacqueline A. Xu, Rebecca Gilbert, Emily Kuczynska-Burggraf, Millicent Tan, Bryan Teede, Helena Vincent, Amanda Gibson-Helm, Melanie Tags: Review Article Source Type: research

What Can You Find about Polycystic Ovary Syndrome (PCOS) Online? Assessing Online Information on PCOS: Quality, Content, and User-Friendliness
Conclusion The majority of PCOS Web sites were commercially derived, targeted women, and were not accredited. There is a significant lack of quality, easy-to-read, evidence-based information online for women with PCOS. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Chiu, Wei-Ling Kuczynska-Burggraf, Millicent Gibson-Helm, Melanie Teede, Helena J. Vincent, Amanda Boyle, Jacqueline A. Tags: Review Article Source Type: research

Evaluation of a Center of Research Excellence in Polycystic Ovary Syndrome as a Large-Scale Collaborative Research Translation Initiative, Including Evaluating Translation of Guideline Impact
Semin Reprod Med 2018; 36: 042-049 DOI: 10.1055/s-0038-1667308Research translation and evaluation are often underconsidered in research design and implementation thus limiting research benefit to the end user. In this article, we first describe a best practice approach to evaluation, for a center of research excellence in polycystic ovary syndrome. Within this, we outline a comprehensive research translation program with inbuilt evaluation of the first International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome (2018). We seek to provide a real-world example of comprehensive approa...
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Garad, Rhonda Kozica-Olenski, Samantha Teede, Helena J. Tags: Review Article Source Type: research

The Needs of Women and Healthcare Providers regarding Polycystic Ovary Syndrome Information, Resources, and Education: A Systematic Search and Narrative Review
This article aims to identify and summarize the information, resource, and education needs of women with polycystic ovary syndrome (PCOS) and their healthcare providers. A systematic search of peer-reviewed, primary research literature was conducted. A total of 4,230 articles were identified, duplicates were removed, as well as the title and abstract of 2,819 studies and the full texts of 123 studies were screened against predetermined inclusion criteria. Findings from 35 included studies are described narratively. Main outcome measures include women's perceived needs for, and experiences of, PCOS care and information; hea...
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Gibson-Helm, Melanie Tassone, Eliza C. Teede, Helena J. Dokras, Anuja Garad, Rhonda Tags: Review Article Source Type: research

Large-Scale Evidence-Based Guideline Development Engaging the International PCOS Community
Semin Reprod Med 2018; 36: 028-034 DOI: 10.1055/s-0038-1667312The evidence-based guideline for the assessment and management of polycystic ovary syndrome (PCOS) integrates the best available evidence with international, multidisciplinary clinical expertise and consumer preferences to provide health professionals, consumers, and policy makers with high-quality, comprehensive guidance about diagnosing and managing PCOS. Here, we outline the rigorous and systematic process, defined a priori and documented to be reproducible, to minimize bias and maintain transparency, in alignment with the Appraisal of Guidelines for Research...
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Misso, Marie L. Tassone, Eliza C. Costello, Michael F. Dokras, Anuja Laven, Joop Moran, Lisa J. Teede, Helena J. Tags: Review Article Source Type: research

Knowledge and Practices Regarding Polycystic Ovary Syndrome among Physicians in Europe, North America, and Internationally: An Online Questionnaire-Based Study
Conclusion Knowledge gaps in PCOS care to be addressed internationally include physician awareness of the breadth of PCOS features, application of diagnostic criteria, and recommending lifestyle management effectively. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Gibson-Helm, Melanie Dokras, Anuja Karro, Helle Piltonen, Terhi Teede, Helena J. Tags: Review Article Source Type: research

Application of Monash Centre for Health Research and Implementation Framework to the Development of Polycycstic Ovary Syndrome Guideline: A Case Study on Implementation
Semin Reprod Med 2018; 36: 013-018 DOI: 10.1055/s-0038-1667311Implementation of healthcare guidelines, a set of recommendations aiming to optimize patient care, can be a complex process which is at risk of poor translation into practice. Failure to adopt new evidence-based healthcare findings can contribute to a large variation in care, potentially affecting outcomes for service users. Designed to avoid this issue, the Monash Centre for Health Research and Implementation (MCHRI) knowledge translation framework was created to support the development and future implementation of clinical practice guidelines. The framework is...
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Robinson, Tracy Skouteris, Helen Melder, Angela Bailey, Cate Morris, Heather Garad, Rhonda Teede, Helena J. Tags: Review Article Source Type: research

A Summary on Polycystic Ovary Syndrome: Diagnostic Criteria, Prevalence, Clinical Manifestations, and Management According to the Latest International Guidelines
Semin Reprod Med 2018; 36: 005-012 DOI: 10.1055/s-0038-1668085Polycystic ovary syndrome (PCOS) is a common hormonal condition with reproductive, metabolic, and psychological sequelae. The Rotterdam Criteria are now internationally accepted, with different phenotypes recognized with varying clinical presentations and risk profiles. The complexity of the disorder, and the impact on quality of life, requires timely diagnosis, screening for complications and management strategies. PCOS remains underdiagnosed and women experience significant delays to diagnosis. Effective dissemination of evidence-based management is therefore ...
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Neven, Adriana Catharina Helena Laven, Joop Teede, Helena J. Boyle, Jacqueline A. Tags: Review Article Source Type: research

A Vision for Improving the Assessment and Management of PCOS through International Collaboration
Semin Reprod Med 2018; 36: 003-004 DOI: 10.1055/s-0038-1667158 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Teede, Helena J. Legro, Richard S. Norman, Robert J. Tags: Preface Source Type: research

The International Guideline in Polycystic Ovary Syndrome
Semin Reprod Med 2018; 36: 001-002 DOI: 10.1055/s-0038-1668119 Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Full text (Source: Seminars in Reproductive Medicine)
Source: Seminars in Reproductive Medicine - September 6, 2018 Category: Reproduction Medicine Authors: Legro, Richard S. Tags: Introduction Source Type: research