Use of Peritoneal Dialysis in Acute Kidney Injury: How Far Away?
Summary: Acute kidney injury (AKI) has become a worldwide public health problem, resulting in a high risk of mortality and progression to chronic kidney disease. Peritoneal dialysis (PD) can be an effective renal support for AKI, especially in regions where medical resources are limited, but actually underused. In this article, the current barriers and challenges of use of PD in AKI are discussed, including health strategy and medical resources, PD team organization, and technique-specific factors. (Source: Seminars in Nephrology)
Source: Seminars in Nephrology - September 1, 2020 Category: Urology & Nephrology Authors: Zhikai Yang, Jie Dong, Li Yang Source Type: research

The Epidemiology and Management of Pediatric AKI in Asia
Because of the lack of early recognition and referral, the incidence of pediatric acute kidney injury (AKI) in Asia still is underestimated. Although each diagnostic criteria has its own merits, the Kidney Disease Improving Global Outcomes classification now is widely accepted. In Asia, the spectrum of pediatric AKI is wide-ranging, from pediatric AKI in highly sophisticated tertiary-care pediatric intensive care units in resource-rich regions due to advanced procedures such as transplantation, cardiac surgery, and other hospital-acquired causes, to primary care preventable causes, such as infectious diseases, snakebite, a...
Source: Seminars in Nephrology - September 1, 2020 Category: Urology & Nephrology Authors: Ruochen Che, Mohammed Mazheruddin Quadri, Aihua Zhang Source Type: research

Introduction: Acute Kidney Injury in Asia, How Far Are We to the 0by25 Initiative?
In 2013, the International Society of Nephrology launched an ambitious initiative called 0by25, which set a goal of eliminating preventable or treatable deaths from acute kidney injury (AKI) by 2025.1 Afterward, nephrologists made great efforts in the improvement of the recognition and management of AKI all over the world.2 In the current issue of Seminars in Nephrology, we focus on AKI in Asia, the world's largest and most populous continent, and show the disease burden and the current status of AKI treatment in various countries and clinical settings. (Source: Seminars in Nephrology)
Source: Seminars in Nephrology - September 1, 2020 Category: Urology & Nephrology Authors: Li Yang Source Type: research

Masthead
(Source: Seminars in Nephrology)
Source: Seminars in Nephrology - September 1, 2020 Category: Urology & Nephrology Source Type: research

Editorial Board
(Source: Seminars in Nephrology)
Source: Seminars in Nephrology - September 1, 2020 Category: Urology & Nephrology Source Type: research

Table of Contents
(Source: Seminars in Nephrology)
Source: Seminars in Nephrology - September 1, 2020 Category: Urology & Nephrology Source Type: research

Nomenclature for Kidney Function and Disease: Executive Summary and Glossary From a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference
A primary obligation of medical journals is the responsible, professional, and expeditious delivery of knowledge from researchers and practitioners to the wider community.1 The task of journal editors, therefore, rests not merely in selecting what to publish, but in large measure judging how it can best be communicated. The challenge of improving descriptions of kidney function and disease in medical publishing was the impetus for a Kidney Disease: Improving Global Outcomes (KDIGO) Consensus Conference held in June 2019. (Source: Seminars in Nephrology)
Source: Seminars in Nephrology - June 30, 2020 Category: Urology & Nephrology Authors: Andrew S. Levey, Kai-Uwe Eckardt, Nijsje M. Dorman, Stacy L. Christiansen, Michael Cheung, Michel Jadoul, Wolfgang C. Winkelmayer Tags: EDITORIAL Source Type: research

Acute Kidney Injury in Active Wars and Other Man-Made Disasters
Summary: Acute kidney injury (AKI) is frequent during wars and other man-made disasters, and contributes significantly to the overall death toll. War-related AKI may develop as a result of polytrauma, traumatic bleeding and hypovolemia, chemical and airborne toxin exposure, and crush syndrome. Thus, prerenal, intrinsic renal, or postrenal AKI may develop at the battlefield, in field hospitals, or tertiary care centers, resulting not only from traumatic, but also nontraumatic, etiologies. The prognosis usually is unfavorable because of systemic and polytrauma-related complications and suboptimal therapeutic interventions. (...
Source: Seminars in Nephrology - June 30, 2020 Category: Urology & Nephrology Authors: Mehmet Sukru Sever, Raymond Vanholder, Norbert Lameire Source Type: research

Introduction: Conflict Nephrology Revisited
Unfortunately, armed conflicts continue to afflict the 21st century. According to the Uppsala Conflict Data Program, the number of war-related armed conflicts around the world has increased sharply in the past few years.1 Most of these conflicts tend to occur in developing countries already suffering from limited resources, weak infrastructure, poor industrial base, and low human development index. Examples of such armed conflicts are many; however, the deadliest over the past few years have transpired in Syria, Afghanistan, Iraq, and Yemen. (Source: Seminars in Nephrology)
Source: Seminars in Nephrology - June 30, 2020 Category: Urology & Nephrology Authors: Sahar H. Koubar, Mohamed H. Sayegh Tags: Introduction Source Type: research

End-Stage Kidney Disease in Areas of Armed Conflicts: Challenges and Solutions
Summary: Violent and protracted conflicts are disastrous to civilian populations and their health care systems. The complex requirements of caring for end-stage kidney disease (ESKD) dialysis patients in such contexts pose unique challenges. Dialysis is procedurally complex and resource-intensive. Delivering ESKD care in man-made conflict settings presents added challenges beyond what is required in natural disasters and resource-limited situations. In this article, we review the medical literature on, and document experience with, managing dialysis ESKD patients in conflict zones. (Source: Seminars in Nephrology)
Source: Seminars in Nephrology - June 30, 2020 Category: Urology & Nephrology Authors: Mohamed Sekkarie, Lina Murad, Akram Al-Makki, Fahd Al-Saghir, Oussama Rifai, Majd Isreb Source Type: research

Impact of Forced Human Migration on Management of End-Stage Kidney Disease in Host Countries
Summary: Forced human migration has affected many populations in the past few decades, the worst has been from Syria, Afghanistan, Kosovo and Venezuela. Neighbouring countries such as Lebanon, Turkey, Jordan, Iran, Macedonia, Albania and Colombia have struggled to provide care to refugees with end-stage kidney disease (ESKD). This review describes and assesses the impact of forced human migration on host countries and the challenges they face when managing refugees with ESKD. Many lessons are learned, most importantly, the urging necessity of establishing health care systems ready to handle an unexpected influx of refugees...
Source: Seminars in Nephrology - June 30, 2020 Category: Urology & Nephrology Authors: Mabel Aoun, Sahar H. Koubar Source Type: research

Peritoneal Dialysis during Active War
Summary: Armed conflict jeopardizes patient care through shortages in vital medical supplies. When health care resources are both scarce and not secure, ethically justified principles of action are required to continue the treatment of patients. Although literature exists on the allocation and treatment decisions for military health care workers and warfighters, scarce literature exist for the use of available resources for civilians living within war zones. Chronic or acute kidney disease patients requiring replacement therapies are among the most vulnerable patient population in this regard. (Source: Seminars in Nephrology)
Source: Seminars in Nephrology - June 30, 2020 Category: Urology & Nephrology Authors: Chad Gorbatkin, Fredric O. Finkelstein, Rumeyza Turan Kazancioglu Source Type: research

Renal Transplantation in Areas of Armed Conflict
Summary: Kidney transplantation (KT) is the treatment of choice for patients with end-stage renal disease. KT recipients are considered a vulnerable patient population because of their dependence on expensive immunosuppression drugs from the time of transplantation until graft failure. Management of KT recipients is complex, and therefore requires a sustainable infrastructure that is equipped to provide reliable medical care and continued access to immunosuppressive drugs. This structure, especially in third-world countries, relies on elements that may be easily disrupted during times of armed conflict. (Source: Seminars in Nephrology)
Source: Seminars in Nephrology - June 30, 2020 Category: Urology & Nephrology Authors: Sami Alasfar, Majd Isreb, Saleh Kaysi, Kamel Hatahet Source Type: research

Role of the International and National Renal Organizations in Natural Disasters: Strategies for Renal Rescue
Summary: Besides loss of life and property, natural disasters result in a number of renal challenges, either by the creation of rhabdomyolysis and crush-induced acute kidney injury or by the destruction of existing dialysis facilities, leaving chronic dialysis patients and kidney transplanted patients without access to their regular dialysis, medications, or medical care. This review describes the organization and the many international interventions of the International Society of Nephrology Renal Disaster Relief Task Force over the past 2 decades. (Source: Seminars in Nephrology)
Source: Seminars in Nephrology - June 30, 2020 Category: Urology & Nephrology Authors: Norbert Lameire, Mehmet Sukru Sever, Wim Van Biesen, Raymond Vanholder Source Type: research

Renal Crisis in Children during Armed Conflict
Summary: Armed conflicts continue to occur in some regions of the globe, mostly in developing countries. These man-made disasters affect all segments of the population; however, some groups are more vulnerable and suffer more seriously from the unfavorable consequences of such conflicts. Among these, the pediatric population deserves special attention because they cannot protect themselves, and hence carry a higher threat of injuries and probability of death during conflicts. In addition, children who do survive the disaster are more prone to exploitation. (Source: Seminars in Nephrology)
Source: Seminars in Nephrology - June 30, 2020 Category: Urology & Nephrology Authors: Lale Sever, Ayse Balat Source Type: research