COVID-19 and the Kidney: Recent Advances and Controversies
Kidney involvement is common in COVID-19, and our understanding of the effects of COVID-19 on short- and long-term kidney outcomes has evolved over the course of the pandemic. Initial key questions centered on the spectrum and degree of acute kidney injury (AKI) in patients hospitalized with severe COVID-19. Investigators worldwide explored the association between COVID-19 –associated AKI and short-term outcomes, including inpatient mortality and disease severity. Even as treatments evolved, vaccinations were developed, and newer viral variants arose, subsets of patients were identified as at continued high risk for majo...
Source: Seminars in Nephrology - October 18, 2022 Category: Urology & Nephrology Authors: Steven Menez, Chirag R. Parikh Source Type: research
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Source: Seminars in Nephrology - September 1, 2022 Category: Urology & Nephrology Source Type: research
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Source: Seminars in Nephrology - September 1, 2022 Category: Urology & Nephrology Source Type: research
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Source: Seminars in Nephrology - September 1, 2022 Category: Urology & Nephrology Source Type: research
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Source: Seminars in Nephrology - September 1, 2022 Category: Urology & Nephrology Source Type: research
Ethical Issues in Kidney Transplant and Donation during COVID-19 pandemic
The Covid-19 pandemic caused by the severe acute respiratory syndrome coronavirus (SARS-CoV-2) has faced the transplant community with unprecedented clinical challenges in a highly vulnerable patient category. These were associated with many uncertainties for patients and healthcare professionals and prompted many ethical debates regarding safe delivery of kidney transplantation. In this paper, we highlight some of the most important ethical questions that were raised during the pandemic and attempt to analyse ethical arguments in the light of core principles of medical ethics to either suspend or continue kidney transplan...
Source: Seminars in Nephrology - July 15, 2022 Category: Urology & Nephrology Authors: Kai-Ming Chow, Umberto Maggiore, Frank J.M.F. Dor Source Type: research
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Source: Seminars in Nephrology - July 1, 2022 Category: Urology & Nephrology Source Type: research
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Source: Seminars in Nephrology - July 1, 2022 Category: Urology & Nephrology Source Type: research
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Source: Seminars in Nephrology - July 1, 2022 Category: Urology & Nephrology Source Type: research
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Source: Seminars in Nephrology - May 1, 2022 Category: Urology & Nephrology Source Type: research
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Source: Seminars in Nephrology - May 1, 2022 Category: Urology & Nephrology Source Type: research
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Source: Seminars in Nephrology - May 1, 2022 Category: Urology & Nephrology Source Type: research
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Source: Seminars in Nephrology - May 1, 2022 Category: Urology & Nephrology Source Type: research
Sex and gender differences in chronic kidney disease and access to care around the globe
The difference between sex, the biological construct, and gender, the social construct, may be most evident in settings of vulnerability. Globally, chronic kidney disease is more prevalent among women, but the prevalence of end-stage kidney failure, and especially receipt of kidney replacement therapy, is higher in men. These differences likely reflect a combination of physiological and social/structural risk factors that independently modulate kidney disease and/or its progression. The distribution of the most common risk factors such as hypertension and obesity differ between men and women and may impact disease risk dif...
Source: Seminars in Nephrology - March 1, 2022 Category: Urology & Nephrology Authors: Guillermo Garc ía García, Arpana Iyengar, François Kaze, Ciara Kierans, Cesar Padilla-Altamira, Valerie A. Luyckx Source Type: research
X-Linked Kidney Disorders in Women
This article reviews the biology of X inactivation as well as the kidney phenotype in women and girls with a number of X-linked kidney disorders including Alport syndrome, Fabry disease, nephrogenic diabetes insipidus, X-linked hypophosphatemic rickets, Dent disease, and Lowe syndrome. (Source: Seminars in Nephrology)
Source: Seminars in Nephrology - March 1, 2022 Category: Urology & Nephrology Authors: Catherine Quinlan, Michelle N. Rheault Source Type: research
