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Melittin alleviates sepsis-induced acute kidney injury by promoting GPX4 expression to inhibit ferroptosis
CONCLUSIONS: Our study reveals the protective mechanism of melittin in septic kidney injury and provides a new therapeutic direction for Sepsis-AKI.PMID:38149613 | PMC:PMC10763831 | DOI:10.1080/13510002.2023.2290864 (Source: Redox Report : communications in free radical research)
Source: Redox Report : communications in free radical research - December 27, 2023 Category: Biochemistry Authors: Hongyan Zan Jizheng Liu Meixia Yang Honghui Zhao Chunyan Gao Yunyan Dai Zhiming Wang Hongxuan Liu Yunfei Zhang Source Type: research

Melittin alleviates sepsis-induced acute kidney injury by promoting GPX4 expression to inhibit ferroptosis
CONCLUSIONS: Our study reveals the protective mechanism of melittin in septic kidney injury and provides a new therapeutic direction for Sepsis-AKI.PMID:38149613 | PMC:PMC10763831 | DOI:10.1080/13510002.2023.2290864 (Source: Redox Report : communications in free radical research)
Source: Redox Report : communications in free radical research - December 27, 2023 Category: Biochemistry Authors: Hongyan Zan Jizheng Liu Meixia Yang Honghui Zhao Chunyan Gao Yunyan Dai Zhiming Wang Hongxuan Liu Yunfei Zhang Source Type: research

Melittin alleviates sepsis-induced acute kidney injury by promoting GPX4 expression to inhibit ferroptosis
CONCLUSIONS: Our study reveals the protective mechanism of melittin in septic kidney injury and provides a new therapeutic direction for Sepsis-AKI.PMID:38149613 | DOI:10.1080/13510002.2023.2290864 (Source: Redox Report : communications in free radical research)
Source: Redox Report : communications in free radical research - December 27, 2023 Category: Biochemistry Authors: Hongyan Zan Jizheng Liu Meixia Yang Honghui Zhao Chunyan Gao Yunyan Dai Zhiming Wang Hongxuan Liu Yunfei Zhang Source Type: research

Melittin alleviates sepsis-induced acute kidney injury by promoting GPX4 expression to inhibit ferroptosis
CONCLUSIONS: Our study reveals the protective mechanism of melittin in septic kidney injury and provides a new therapeutic direction for Sepsis-AKI.PMID:38149613 | DOI:10.1080/13510002.2023.2290864 (Source: Redox Report : communications in free radical research)
Source: Redox Report : communications in free radical research - December 27, 2023 Category: Biochemistry Authors: Hongyan Zan Jizheng Liu Meixia Yang Honghui Zhao Chunyan Gao Yunyan Dai Zhiming Wang Hongxuan Liu Yunfei Zhang Source Type: research

Melittin alleviates sepsis-induced acute kidney injury by promoting GPX4 expression to inhibit ferroptosis
CONCLUSIONS: Our study reveals the protective mechanism of melittin in septic kidney injury and provides a new therapeutic direction for Sepsis-AKI.PMID:38149613 | DOI:10.1080/13510002.2023.2290864 (Source: Redox Report : communications in free radical research)
Source: Redox Report : communications in free radical research - December 27, 2023 Category: Biochemistry Authors: Hongyan Zan Jizheng Liu Meixia Yang Honghui Zhao Chunyan Gao Yunyan Dai Zhiming Wang Hongxuan Liu Yunfei Zhang Source Type: research

Melittin alleviates sepsis-induced acute kidney injury by promoting GPX4 expression to inhibit ferroptosis
CONCLUSIONS: Our study reveals the protective mechanism of melittin in septic kidney injury and provides a new therapeutic direction for Sepsis-AKI.PMID:38149613 | DOI:10.1080/13510002.2023.2290864 (Source: Redox Report : communications in free radical research)
Source: Redox Report : communications in free radical research - December 27, 2023 Category: Biochemistry Authors: Hongyan Zan Jizheng Liu Meixia Yang Honghui Zhao Chunyan Gao Yunyan Dai Zhiming Wang Hongxuan Liu Yunfei Zhang Source Type: research

Melittin alleviates sepsis-induced acute kidney injury by promoting GPX4 expression to inhibit ferroptosis
CONCLUSIONS: Our study reveals the protective mechanism of melittin in septic kidney injury and provides a new therapeutic direction for Sepsis-AKI.PMID:38149613 | DOI:10.1080/13510002.2023.2290864 (Source: Redox Report : communications in free radical research)
Source: Redox Report : communications in free radical research - December 27, 2023 Category: Biochemistry Authors: Hongyan Zan Jizheng Liu Meixia Yang Honghui Zhao Chunyan Gao Yunyan Dai Zhiming Wang Hongxuan Liu Yunfei Zhang Source Type: research

Melittin alleviates sepsis-induced acute kidney injury by promoting GPX4 expression to inhibit ferroptosis
CONCLUSIONS: Our study reveals the protective mechanism of melittin in septic kidney injury and provides a new therapeutic direction for Sepsis-AKI.PMID:38149613 | DOI:10.1080/13510002.2023.2290864 (Source: Redox Report : communications in free radical research)
Source: Redox Report : communications in free radical research - December 27, 2023 Category: Biochemistry Authors: Hongyan Zan Jizheng Liu Meixia Yang Honghui Zhao Chunyan Gao Yunyan Dai Zhiming Wang Hongxuan Liu Yunfei Zhang Source Type: research

Integrated approach to reducing polypharmacy in older people: exploring the role of oxidative stress and antioxidant potential therapy
Redox Rep. 2024 Dec;29(1):2289740. doi: 10.1080/13510002.2023.2289740. Epub 2023 Dec 18.ABSTRACTIncreased life expectancy, attributed to improved access to healthcare and drug development, has led to an increase in multimorbidity, a key contributor to polypharmacy. Polypharmacy is characterised by its association with a variety of adverse events in the older persons. The mechanisms involved in the development of age-related chronic diseases are largely unknown; however, altered redox homeostasis due to ageing is one of the main theories. In this context, the present review explores the development and interaction between d...
Source: Redox Report : communications in free radical research - December 18, 2023 Category: Biochemistry Authors: Catalina Rojas-Sol é V íctor Pinilla-González Jos é Lillo-Moya Tommy Gonz ález-Fernández Luciano Saso Ram ón Rodrigo Source Type: research

Integrated approach to reducing polypharmacy in older people: exploring the role of oxidative stress and antioxidant potential therapy
Redox Rep. 2024 Dec;29(1):2289740. doi: 10.1080/13510002.2023.2289740. Epub 2023 Dec 18.ABSTRACTIncreased life expectancy, attributed to improved access to healthcare and drug development, has led to an increase in multimorbidity, a key contributor to polypharmacy. Polypharmacy is characterised by its association with a variety of adverse events in the older persons. The mechanisms involved in the development of age-related chronic diseases are largely unknown; however, altered redox homeostasis due to ageing is one of the main theories. In this context, the present review explores the development and interaction between d...
Source: Redox Report : communications in free radical research - December 18, 2023 Category: Biochemistry Authors: Catalina Rojas-Sol é V íctor Pinilla-González Jos é Lillo-Moya Tommy Gonz ález-Fernández Luciano Saso Ram ón Rodrigo Source Type: research

Integrated approach to reducing polypharmacy in older people: exploring the role of oxidative stress and antioxidant potential therapy
Redox Rep. 2024 Dec;29(1):2289740. doi: 10.1080/13510002.2023.2289740. Epub 2023 Dec 18.ABSTRACTIncreased life expectancy, attributed to improved access to healthcare and drug development, has led to an increase in multimorbidity, a key contributor to polypharmacy. Polypharmacy is characterised by its association with a variety of adverse events in the older persons. The mechanisms involved in the development of age-related chronic diseases are largely unknown; however, altered redox homeostasis due to ageing is one of the main theories. In this context, the present review explores the development and interaction between d...
Source: Redox Report : communications in free radical research - December 18, 2023 Category: Biochemistry Authors: Catalina Rojas-Sol é V íctor Pinilla-González Jos é Lillo-Moya Tommy Gonz ález-Fernández Luciano Saso Ram ón Rodrigo Source Type: research

Integrated approach to reducing polypharmacy in older people: exploring the role of oxidative stress and antioxidant potential therapy
Redox Rep. 2024 Dec;29(1):2289740. doi: 10.1080/13510002.2023.2289740. Epub 2023 Dec 18.ABSTRACTIncreased life expectancy, attributed to improved access to healthcare and drug development, has led to an increase in multimorbidity, a key contributor to polypharmacy. Polypharmacy is characterised by its association with a variety of adverse events in the older persons. The mechanisms involved in the development of age-related chronic diseases are largely unknown; however, altered redox homeostasis due to ageing is one of the main theories. In this context, the present review explores the development and interaction between d...
Source: Redox Report : communications in free radical research - December 18, 2023 Category: Biochemistry Authors: Catalina Rojas-Sol é V íctor Pinilla-González Jos é Lillo-Moya Tommy Gonz ález-Fernández Luciano Saso Ram ón Rodrigo Source Type: research

Integrated approach to reducing polypharmacy in older people: exploring the role of oxidative stress and antioxidant potential therapy
Redox Rep. 2024 Dec;29(1):2289740. doi: 10.1080/13510002.2023.2289740. Epub 2023 Dec 18.ABSTRACTIncreased life expectancy, attributed to improved access to healthcare and drug development, has led to an increase in multimorbidity, a key contributor to polypharmacy. Polypharmacy is characterised by its association with a variety of adverse events in the older persons. The mechanisms involved in the development of age-related chronic diseases are largely unknown; however, altered redox homeostasis due to ageing is one of the main theories. In this context, the present review explores the development and interaction between d...
Source: Redox Report : communications in free radical research - December 18, 2023 Category: Biochemistry Authors: Catalina Rojas-Sol é V íctor Pinilla-González Jos é Lillo-Moya Tommy Gonz ález-Fernández Luciano Saso Ram ón Rodrigo Source Type: research

Integrated approach to reducing polypharmacy in older people: exploring the role of oxidative stress and antioxidant potential therapy
Redox Rep. 2024 Dec;29(1):2289740. doi: 10.1080/13510002.2023.2289740. Epub 2023 Dec 18.ABSTRACTIncreased life expectancy, attributed to improved access to healthcare and drug development, has led to an increase in multimorbidity, a key contributor to polypharmacy. Polypharmacy is characterised by its association with a variety of adverse events in the older persons. The mechanisms involved in the development of age-related chronic diseases are largely unknown; however, altered redox homeostasis due to ageing is one of the main theories. In this context, the present review explores the development and interaction between d...
Source: Redox Report : communications in free radical research - December 18, 2023 Category: Biochemistry Authors: Catalina Rojas-Sol é V íctor Pinilla-González Jos é Lillo-Moya Tommy Gonz ález-Fernández Luciano Saso Ram ón Rodrigo Source Type: research

Integrated approach to reducing polypharmacy in older people: exploring the role of oxidative stress and antioxidant potential therapy
Redox Rep. 2024 Dec;29(1):2289740. doi: 10.1080/13510002.2023.2289740. Epub 2023 Dec 18.ABSTRACTIncreased life expectancy, attributed to improved access to healthcare and drug development, has led to an increase in multimorbidity, a key contributor to polypharmacy. Polypharmacy is characterised by its association with a variety of adverse events in the older persons. The mechanisms involved in the development of age-related chronic diseases are largely unknown; however, altered redox homeostasis due to ageing is one of the main theories. In this context, the present review explores the development and interaction between d...
Source: Redox Report : communications in free radical research - December 18, 2023 Category: Biochemistry Authors: Catalina Rojas-Sol é V íctor Pinilla-González Jos é Lillo-Moya Tommy Gonz ález-Fernández Luciano Saso Ram ón Rodrigo Source Type: research