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Licochalcone B confers protective effects against LPS-Induced acute lung injury in cells and mice through the Keap1/Nrf2 pathway
CONCLUSION: LCB protects against LPS-induced acute lung injury in cells and mice. The Keap1/Nrf2 pathway may be involved in its protective effects. LCB shows potential as a strategy to alleviate ALI caused by LPS.PMID:37565601 | DOI:10.1080/13510002.2023.2243423 (Source: Redox Report : communications in free radical research)
Source: Redox Report : communications in free radical research - August 11, 2023 Category: Biochemistry Authors: Ju Huang Yu Zhu Songtao Li Huanyu Jiang Nianzhi Chen Hang Xiao Jingwen Liu Dan Liang Qiao Zheng Jianyuan Tang Xiangrui Meng Source Type: research

Reduction of butyric acid-producing bacteria in the ileal mucosa-associated microbiota is associated with the history of abdominal surgery in patients with Crohn's disease
Redox Rep. 2023 Dec;28(1):2241615. doi: 10.1080/13510002.2023.2241615.ABSTRACTFecal microbiota is a significant factor determining the cause, course, and prognosis of Crohn's disease (CD). However, the factors affecting mucosa-associated microbiota (MAM) remain unclear. This retrospective study examined the differences in ileal MAM between CD patients and healthy controls and investigated the factors affecting MAM in CD patients to clarify potential therapeutic targets. Ileal MAM was obtained using brush forceps during endoscopic examination from 23 healthy controls and 32 CD patients (most were in remission). The samples'...
Source: Redox Report : communications in free radical research - August 2, 2023 Category: Biochemistry Authors: Osamu Handa Hiroto Miura Tingting Gu Motoyasu Osawa Hiroshi Matsumoto Eiji Umegaki Ryo Inoue Yuji Naito Akiko Shiotani Source Type: research

Salidroside affects the Th17/Treg cell balance in aplastic anemia via the STAT3/HIF-1 α/RORγt pathway
CONCLUSION: Salidroside has potential as a novel AA treatment by correcting the Th17/Treg imbalance through the STAT3/HIF-1α/RORγt pathway.PMID:37439434 | PMC:PMC10348039 | DOI:10.1080/13510002.2023.2225868 (Source: Redox Report : communications in free radical research)
Source: Redox Report : communications in free radical research - July 13, 2023 Category: Biochemistry Authors: Zenghui Liu Lixuan Chen Defang Xiong Yu Zhan Jiduo Liu Ling Ouyang Wancheng Chen Ziyuan Lu Tianqi Gao Xiaozhen Li Yanqun Zhou Xuekui Gu Yang Xiao Source Type: research