Domain swap facilitates structural transitions of spider silk protein C ‐terminal domains
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - September 15, 2023 Category: Biochemistry Authors: Charlotte Rat,
Cedric Heindl,
Hannes Neuweiler Tags: RESEARCH ARTICLE Source Type: research
The molecular details of a novel phosphorylation ‐dependent interaction between MRN and the SOSS complex
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - September 15, 2023 Category: Biochemistry Authors: Serene El ‐Kamand,
Mark N. Adams,
Jacqueline M. Matthews,
Mar‐Dean Du Plessis,
Ben Crossett,
Angela Connolly,
Natasha Breen,
Alexander Dudley,
Derek J. Richard,
Roland Gamsjaeger,
Liza Cubeddu Tags: RESEARCH ARTICLE Source Type: research
Amber ‐codon suppression for spatial localization and in vivo photoaffinity capture of the interactome of the Pseudomonas aeruginosa Rare Lipoprotein A (RlpA) lytic transglycosylase
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - September 14, 2023 Category: Biochemistry Authors: Luis F. Avila ‐Cobian,
Hidekazu Hoshino,
Mark E. Horsman,
Van T. Nguyen,
Yuanyuan Qian,
Rhona Feltzer,
Choon Kim,
Daniel D. Hu,
Matthew M. Champion,
Jed F. Fisher,
Shahriar Mobashery Tags: RESEARCH ARTICLE Source Type: research
Cover Image
Chemical similarity across the co-crystallized inhibitors of EGFR mutant (T790M/L858R) highlights the chemical landscape variation. For details, see: Agneesh Pratim Das et al., Protein Science, 2023.https://doi.org/10.1002/pro.4740 (Source: Protein Science)
Source: Protein Science - September 13, 2023 Category: Biochemistry Tags: Cover Image Source Type: research
Issue information
(Source: Protein Science)
Source: Protein Science - September 13, 2023 Category: Biochemistry Tags: Issue Information Source Type: research
Zero ‐shot Mutation Effect Prediction on Protein Stability and Function using RoseTTAFold
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - September 12, 2023 Category: Biochemistry Authors: Sanaa Mansoor,
Minkyung Baek,
David Juergens,
Joseph L. Watson,
David Baker Tags: RESEARCH NOTE Source Type: research
Enantioselectivity in the Enzymatic Dehydration of Malate and Tartrate: Mirror Image Specificities of Structurally Similar Dehydratases
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - September 11, 2023 Category: Biochemistry Authors: Asutosh Bellur,
Souradip Mukherjee,
Pragya Sharma,
Vijay Jayaraman,
Hemalatha Balaram Tags: RESEARCH NOTE Source Type: research
The antimicrobial peptide database is 20 years old: Recent developments and future directions
This article highlights new database additions and findings. To facilitate antimicrobial development to combat drug-resistant pathogens, the APD has been re-annotating the data for antibacterial activity (active, inactive, and uncertain), toxicity (hemolytic and non-hemolytic AMPs), and salt tolerance (salt sensitive and insensitive). Comparison of the respective desired and undesired AMP groups produces new knowledge for peptide design. Our unification of AMPs from the six life kingdoms into “natural AMPs” enabled the first comparison with globular or transmembrane proteins. Due to the dominance of amphipathic helical...
Source: Protein Science - September 11, 2023 Category: Biochemistry Authors: Guangshun Wang Tags: TOOLS FOR PROTEIN SCIENCE Source Type: research
Kalium 3.0 is a comprehensive depository of natural, artificial, and labeled polypeptides acting on potassium channels
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - September 9, 2023 Category: Biochemistry Authors: Nikolay A. Krylov,
Valentin M. Tabakmakher,
Daria A. Yureva,
Alexander A. Vassilevski,
Alexey I. Kuzmenkov Tags: TOOLS FOR PROTEIN SCIENCE Source Type: research
Elucidation of binding mechanism, affinity and complex structure between mWT1 tumor ‐associated antigen peptide and HLA‐A*24:02
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - September 5, 2023 Category: Biochemistry Authors: Gert ‐Jan Bekker,
Nobutaka Numoto,
Maki Kawasaki,
Takahiro Hayashi,
Saaya Yabuno,
Yuko Kozono,
Takeyuki Shimizu,
Haruo Kozono,
Nobutoshi Ito,
Masayuki Oda,
Narutoshi Kamiya Tags: RESEARCH ARTICLE Source Type: research
Biophysical Investigation of Interactions Between SARS ‐CoV‐2 Spike Protein and Neuropilin‐1
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - September 2, 2023 Category: Biochemistry Authors: Decheng Hou,
Wenpeng Cao,
Seonghan Kim,
Xinyu Cui,
Matthew Ziarnik,
Im Wonpil,
X. Frank Zhang Tags: RESEARCH ARTICLE Source Type: research
Rational design of small ‐molecule responsive protein switches
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - September 1, 2023 Category: Biochemistry Authors: Sailan Shui,
Stephen Buckley,
Leo Scheller,
Bruno E. Correia Tags: REVIEW ARTICLE Source Type: research
Structural characterization of an intrinsically disordered protein complex using integrated small ‐angle neutron scattering and computing
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - August 31, 2023 Category: Biochemistry Authors: Serena H. Chen,
Kevin L. Weiss,
Christopher Stanley,
Debsindhu Bhowmik Tags: RESEARCH ARTICLE Source Type: research
ParSe 2.0: A web tool to identify drivers of protein phase separation at the proteome level
AbstractWe have developed an algorithm, ParSe, which accurately identifies from the primary sequence those protein regions likely to exhibit physiological phase separation behavior. Originally, ParSe was designed to test the hypothesis that, for flexible proteins, phase separation potential is correlated to hydrodynamic size. While our results were consistent with that idea, we also found that many different descriptors could successfully differentiate between three classes of protein regions: folded, intrinsically disordered, and phase-separating intrinsically disordered. Consequently, numerous combinations of amino acid ...
Source: Protein Science - August 29, 2023 Category: Biochemistry Authors: Colorado Wilson,
Karen A. Lewis,
Nicholas C. Fitzkee,
Loren E. Hough,
Steven T. Whitten Tags: TOOLS FOR PROTEIN SCIENCE Source Type: research
Autoantibody discovery from mammalian total cellular protein separated by hydrophobicity and molecular mass under fully denatured and nucleic acids free condition
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - August 29, 2023 Category: Biochemistry Authors: Mirei Date,
Ai Miyamoto,
Tomoko Honjo,
Tsugumi Shiokawa,
Hiroko Tada,
Nobuhiro Okada,
Junichiro Futami Tags: METHODS AND APPLICATIONS Source Type: research
