Cover Image
A combination of thermodynamic analysis, X-ray crystallography, and molecular dynamics (MD) simulations have revealed the molecular mechanism by which an arginine cluster introduced in the framework region of an Fab antibody enhanced affinity toward its antigen. For details, see: Shingo Maeta et al., Protein Science, 2023.https://doi.org/10.1002/pro.4745 (Source: Protein Science)
Source: Protein Science - October 14, 2023 Category: Biochemistry Tags: Cover Image Source Type: research
DUF916 and DUF3324 in the WxL protein cluster bind to WxL and link bacterial and host surfaces
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 14, 2023 Category: Biochemistry Authors: Mahreen U. Hassan,
Roy R. Chaudhuri,
Mike P. Williamson Tags: RESEARCH ARTICLE Source Type: research
Coronaviruses Spike glycoprotein endodomains: the sequence and structure ‐based comprehensive study
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 14, 2023 Category: Biochemistry Authors: Prateek Kumar,
Aparna Bhardwaj,
Bodhidipra Mukherjee,
Richa Joshi,
Rajanish Giri Tags: RESEARCH ARTICLE Source Type: research
14 ‐3‐3 protein inhibits CaMKK1 by blocking the kinase active site with its last two C‐terminal helices
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 11, 2023 Category: Biochemistry Authors: Olivia Petrvalska,
Karolina Honzejkova,
Nicola Koupilova,
Petr Herman,
Veronika Obsilova,
Tomas Obsil Tags: RESEARCH ARTICLE Source Type: research
Engineering Minimal Tissue Inhibitors of Metalloproteinase Targeting MMPs via Gene Shuffling and Yeast Surface Display
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 9, 2023 Category: Biochemistry Authors: Arman Hosseini,
Sachin Kumar,
Kyle Hedin,
Maryam Raeeszadeh ‐Sarmazdeh Tags: RESEARCH ARTICLE Source Type: research
Photomodulation of the ASIC1a acidic pocket destabilizes the open state
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 8, 2023 Category: Biochemistry Authors: Matthew L. Rook,
Tyler W. McCullock,
Tyler Couch,
John D. Lueck,
David M. MacLean Tags: RESEARCH ARTICLE Source Type: research
Side ‐Chain Dynamics of the α1B‐Adrenergic Receptor determined by NMR via Methyl Relaxation
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 8, 2023 Category: Biochemistry Authors: Christian Baumann,
Wan ‐Chin Chiang,
Renato Valsecchi,
Simon Jurt,
Mattia Deluigi,
Matthias Schuster,
Karl Johan Rosengren,
Andreas Plückthun,
Oliver Zerbe Tags: RESEARCH ARTICLE Source Type: research
On the regulation of human D ‐aspartate oxidase
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 8, 2023 Category: Biochemistry Authors: Valentina Rabattoni,
Zoraide Motta,
Matteo Miceli,
Gianluca Molla,
Alex Fissore,
Salvatore Adinolfi,
Loredano Pollegioni,
Silvia Sacchi Tags: RESEARCH ARTICLE Source Type: research
One ‐step site‐specific S‐alkylation of full‐length caveolin‐1: Lipidation modulates the topology of its C‐terminal domain
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 7, 2023 Category: Biochemistry Authors: Jeffrey A. Julien,
Alain Rousseau,
Thomas V. Perone,
David M. LaGatta,
Chan Hong,
Kyle T. Root,
Soohyung Park,
Ren é Fuanta,
Wonpil Im,
Kerney Jebrell Glover Tags: RESEARCH ARTICLE Source Type: research
Identification and Characterization of a Small Molecule that Activates Thiosulfate Sulfurtransferase and Stimulates Mitochondrial Respiration
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 6, 2023 Category: Biochemistry Authors: Zayana M. AL ‐Dahmani,
Mojgan Hadian,
Angel J. Ruiz‐Moreno,
Sabogal‐Guaqueta Angelica Maria,
Fernando A. Batista,
Ran Zhang,
Yang Luo,
Afsaneh Sadremomtaz,
Robin van der Straat,
Mette Spoor,
Amalia M. Dolga,
Frank J. Dekker,
Alexander D Tags: RESEARCH ARTICLE Source Type: research
Retracing the evolution of a modern periplasmic binding protein
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 4, 2023 Category: Biochemistry Authors: Florian Michel,
Sergio Romero ‐Romero,
Birte Höcker Tags: RESEARCH ARTICLE Source Type: research
Controlling the interaction between CaMKII and Calmodulin with a photocrosslinking unnatural amino acid
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 3, 2023 Category: Biochemistry Authors: Iva Lu čić,
Pin‐Lian Jiang,
Andreas Franz,
Yuval Bursztyn,
Fan Liu,
Andrew J. R. Plested Tags: RESEARCH ARTICLE Source Type: research
Probing macromolecular crowding at the lipid membrane interface with genetically ‐encoded sensors
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 2, 2023 Category: Biochemistry Authors: Maryna L öwe,
Sebastian Hänsch,
Eymen Hachani,
Lutz Schmitt,
Stefanie Weidtkamp‐Peters,
Alexej Kedrov Tags: RESEARCH ARTICLE Source Type: research
Characterization of the inner membrane cytochrome ImcH from Geobacter reveals its importance for extracellular electron transfer and energy conservation
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - October 2, 2023 Category: Biochemistry Authors: Andreia I. Pimenta,
Catarina M. Paquete,
Leonor Morgado,
Marcus J. Edwards,
Thomas A. Clarke,
Carlos A. Salgueiro,
In ês A. C. Pereira,
Américo G. Duarte Tags: RESEARCH ARTICLE Source Type: research
In silico protein dynamics in the human cytoplasm: partial folding, misfolding, fold switching, and non ‐native interactions
This study demonstrates that even fast-folding proteins can get stuck in non-native states in the cell, making them useful models for protein-chaperone interactions and early stages of aggregate formation relevant to cellular disease.This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - September 30, 2023 Category: Biochemistry Authors: Premila P. Samuel Russell,
Meredith M. Rickard,
Mayank Boob,
Martin Gruebele,
Taras V. Pogorelov Tags: RESEARCH ARTICLE Source Type: research
