Structural insights into the unique recognition module between α‐synuclein peptide and nanobody
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - December 18, 2023 Category: Biochemistry Authors: Zeyaul Islam, Nishant N. Vaikath, Issam Hmila, Omar M. A. El ‐Agnaf, Prasanna R. Kolatkar Tags: RESEARCH ARTICLE Source Type: research

Issue information
(Source: Protein Science)
Source: Protein Science - December 17, 2023 Category: Biochemistry Tags: Issue Information Source Type: research

Cover Image
Site-specific photo-crosslinking/cleavage, using genetic code expansion technologies, enables identification of protein-protein interface. The method reveals that at least two interfaces are involved in the homophilic interaction of lysosomal-associated membrane protein type 2A (LAMP2A) in mammalian cells (upper panels), which requires a trimeric or higher oligomeric assembly of adjacent LAMP2A molecules (lower panels). For details, see: Terasawa and Seike et al., Protein Science, 2023.https://doi.org/10.1002/pro.4823 (Source: Protein Science)
Source: Protein Science - December 16, 2023 Category: Biochemistry Tags: Cover Image Source Type: research

Structure ‐based insights into the mechanism of [4Fe‐4S]‐dependent sulfur insertase LarE
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - December 16, 2023 Category: Biochemistry Authors: Paolo Zecchin, Ludovic Pecqueur, Jonathan Oltmanns, Christophe Velours, Volker Sch ünemann, Marc Fontecave, Béatrice Golinelli‐Pimpaneau Tags: RESEARCH ARTICLE Source Type: research

Kinetic evidence for multiple aggregation pathways in antibody light chain variable domains
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Source: Protein Science - December 15, 2023 Category: Biochemistry Authors: Sherry Wong, Madeline E. West, Gareth J. Morgan Tags: RESEARCH ARTICLE Source Type: research

Emerging role of carbonyl ‐carbonyl interactions in the classification of beta turns
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - December 15, 2023 Category: Biochemistry Authors: Nancy D'Arminio, Valentina Ruggiero, Giovanni Pierri, Anna Marabotti, Consiglia Tedesco Tags: RESEARCH ARTICLE Source Type: research

FRAGSITE2: A Structure and Fragment Based Approach for Virtual Ligand Screening
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Source: Protein Science - December 15, 2023 Category: Biochemistry Authors: Hongyi Zhou, Jeffrey Skolnick Tags: TOOLS FOR PROTEIN SCIENCE Source Type: research

Evidence of direct interaction between cisplatin and the caspase ‐cleaved prostate apoptosis response‐4 (cl‐Par‐4) tumor suppressor
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - December 14, 2023 Category: Biochemistry Authors: Krishna K. Raut, Andrea M. Clark, Samjhana Pandey, Gyanendra Kharel, Steven M. Pascal Tags: RESEARCH ARTICLE Source Type: research

Semi ‐synthetic nanobody‐ligand conjugates exhibit tunable signaling properties and enhanced transcriptional outputs at neurokinin receptor‐1
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - December 13, 2023 Category: Biochemistry Authors: Nayara Braga Emidio, Ross W. Cheloha Tags: RESEARCH ARTICLE Source Type: research

Assessing Computational Tools for Predicting Protein Stability Changes upon Missense Mutations Using a New Dataset
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Source: Protein Science - December 12, 2023 Category: Biochemistry Authors: Feifan Zheng, Yang Liu, Yan Yang, Yuhao Wen, Minghui Li Tags: RESEARCH ARTICLE Source Type: research

A Significance Score for Protein ‐Protein Interaction Models Through Random Docking
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Source: Protein Science - December 11, 2023 Category: Biochemistry Authors: Katherine Maia McCoy, Margaret E. Ackerman, Gevorg Grigoryan Tags: RESEARCH ARTICLE Source Type: research

Evaluation of AlphaFold Antibody ‐Antigen Modeling with Implications for Improving Predictive Accuracy
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - December 11, 2023 Category: Biochemistry Authors: Rui Yin, Brian G. Pierce Tags: RESEARCH ARTICLE Source Type: research

The intrinsically disordered transcriptional activation domain of CIITA is functionally tuneable by single substitutions: An exception or a new paradigm?
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - December 11, 2023 Category: Biochemistry Authors: Shwetha Sreenivasan, Paul Heffren, Kyung ‐Shin Suh, Mykola V. Rodnin, Edina Kosa, Aron W. Fenton, Alexey S. Ladokhin, Paul E. Smith, Joseph D. Fontes, Liskin Swint‐Kruse Tags: RESEARCH ARTICLE Source Type: research

Escherichia coli strains with precise domain deletions in the ribonuclease RNase E can achieve greatly enhanced levels of membrane protein production
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - December 11, 2023 Category: Biochemistry Authors: Eleni Vasilopoulou, Tania Chroumpi, Georgios Skretas Tags: RESEARCH ARTICLE Source Type: research

Direct evidence of lipid transport by the Drs2 ‐Cdc50 flippase upon truncation of its terminal regions
This article is protected by copyright. All rights reserved. (Source: Protein Science)
Source: Protein Science - December 9, 2023 Category: Biochemistry Authors: Sara Abad Herrera, Bo H øjen Justesen, Thibaud Dieudonné, Cédric Montigny, Poul Nissen, Guillaume Lenoir, Thomas Günther Pomorski Tags: RESEARCH ARTICLE Source Type: research