Biliary atresia: the development, pathological features, and classification of the bile duct
AbstractBiliary atresia is an occlusive biliary disease involving intrahepatic and extrahepatic bile ducts. Its etiology and pathogenesis are unclear. There are many manifestations of bile duct involvement in biliary atresia, but little is known about its occurrence and development. In addition, different classification methods have been proposed in different periods of biliary atresia, each with its advantages and disadvantages. The combined application of biliary atresia classification will help to improve the survival rate of patients with native liver. Therefore, this article reviews the development, pathological featu...
Source: Pediatric Surgery International - January 30, 2024 Category: Surgery Source Type: research
Neurodevelopmental impairment following surgical necrotizing enterocolitis with gestational age ≥ 28 weeks: who is at risk?
ConclusionsOur study identified gestational age ≤ 32 weeks, assisted mechanical ventilation after NEC onset, postoperative acute kidney injury, CRP day 3 after NEC onset, and time from presentation to surgery as significant risk factors for NDI in neonates with surgical NEC. These factors would be helpful to refine treatment modalities fo r better disease outcomes. We also determined the cut-off values of CRP day 3 after NEC onset and time from presentation to surgery, allowing for the individualized evaluation of NDI risk and the implementation of earlier targeted laparotomy. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - January 29, 2024 Category: Surgery Source Type: research
Chest drains after open paediatric lung resections: not always required
ConclusionsChest drains may not always be required following open paediatric lung resection. The selective omission of a chest drain following open lung resection, does not appear to result in a significantly higher rate of complications or reintervention, and is associated with significantly shorter hospital length of stay. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - January 27, 2024 Category: Surgery Source Type: research
Validation of the predictive model for operative intervention after blunt abdominal trauma in children with equivocal computed tomography findings: a multi-institutional study
ConclusionsA clinical and radiologic prediction rule was validated using a large multi-institutional dataset of pediatric BAT patients, demonstrating a high degree of accuracy in identifying children who underwent surgery. FF, SOI, and TLF are the most important factors associated with the need for surgical intervention.Level of evidence: Level III. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - January 25, 2024 Category: Surgery Source Type: research
High incidence of EDNRB gene mutation in seven southern Chinese familial cases with Hirschsprung ’s disease
ConclusionWe identified a novel EDNRB (deleted C and inserted TT) mutation in this study using WES. Heterozygote variations in EDNRB gene were significantly enriched in three families and RET mutations were identified in one family. EDNRB variants showed an overall higher incidence and penetrance than RET in southern Chinese families cases. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - January 22, 2024 Category: Surgery Source Type: research
Hirschsprung disease: a cost analysis study of the direct, indirect costs and financial coping strategies for the surgical management in Western Uganda
ConclusionDespite the availability of ‘free care’ from government hospital and non-profit services, this study found that surgical management of Hirschsprung disease imposed substantial cost burden on families with Hirschsprung disease patients. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - January 22, 2024 Category: Surgery Source Type: research
Long-term outcome for children undergoing open hepatico-jejunostomy for choledochal malformations: a 43-year single-center experience
ConclusionOur experience suggests that open complete excision of CMs with HJ achieves excellent results in terms of long-term postoperative outcomes. However, since the most severe complications can occur many years after surgery, international cooperation is advisable to define a precise transitional care follow-up protocol. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - January 19, 2024 Category: Surgery Source Type: research
Human milk oligosaccharides promote intestinal epithelium regeneration independent of the microbiota during necrotizing enterocolitis
ConclusionThis study demonstrates that HMOs promoted intestinal epithelial regeneration independent of the gut microbiota. These findings provide further insight into the various benefits HMOs may have in the protection against NEC. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - January 12, 2024 Category: Surgery Source Type: research
Advantages of single-site laparoscopic orchiopexy for palpable undescended testes in children: a prospective comparison study
ConclusionSingle-site laparoscopic orchiopexy offers superior cosmetic results and comparable success rates compared to conventional laparoscopic orchiopexy for palpable undescended testes. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - January 12, 2024 Category: Surgery Source Type: research
Effectiveness of preoperative ultrasonography in predicting metachronous contralateral inguinal hernia in children: a single-arm prospective study using a historical control for comparison
ConclusionsPreoperative ultrasonography of the contralateral groin is currently unable to accurately detect CPPV, but it appears to be a promising method in predicting MCIH by using rigorous diagnosing criteria. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - January 11, 2024 Category: Surgery Source Type: research
