The mechanism of intestinal stem cells differentiation after ischemia –reperfusion injury in a rat model
ConclusionsIntestinal stem-cell differentiation is toward secretory cells 48  h after IR injury; however, Wnt/β-catenin pathway inhibition and Notch-related gene expression stimulation suggest crosstalk between pathways. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

Rectal biopsy: is it really necessary in anorectal malformations?
ConclusionsOur results strongly suggest that the association of ARM and HD is extremely rare and the practice of searching for ganglia in the distal rectum or fistula of ARM patients should be discouraged to avoid potential misdiagnosis and overtreatment. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

The mechanism of intestinal stem cells differentiation after ischemia –reperfusion injury in a rat model
ConclusionsIntestinal stem-cell differentiation is toward secretory cells 48  h after IR injury; however, Wnt/β-catenin pathway inhibition and Notch-related gene expression stimulation suggest crosstalk between pathways. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

Argon inhalation attenuates systemic inflammation and rescues lung architecture during experimental neonatal sepsis
ConclusionsOur findings suggest that argon inhalation as a novel treatment for neonatal sepsis, reducing mortality and counteracting the acute systemic inflammatory response in the blood and preserving the architecture of the lung. This research can contribute to a paradigm shift in the treatment and outcome of neonates with sepsis. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

Rectal biopsy: is it really necessary in anorectal malformations?
ConclusionsOur results strongly suggest that the association of ARM and HD is extremely rare and the practice of searching for ganglia in the distal rectum or fistula of ARM patients should be discouraged to avoid potential misdiagnosis and overtreatment. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

Argon inhalation attenuates systemic inflammation and rescues lung architecture during experimental neonatal sepsis
ConclusionsOur findings suggest that argon inhalation as a novel treatment for neonatal sepsis, reducing mortality and counteracting the acute systemic inflammatory response in the blood and preserving the architecture of the lung. This research can contribute to a paradigm shift in the treatment and outcome of neonates with sepsis. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

A simple machine learning approach for preoperative diagnosis of esophageal burns after caustic substance ingestion in children
ConclusionsArtificial intelligence systems have a high potential to be used in the prediction of caustic burns in pediatric age groups. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 13, 2023 Category: Surgery Source Type: research

Letter to the Editor
(Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 13, 2023 Category: Surgery Source Type: research

A simple machine learning approach for preoperative diagnosis of esophageal burns after caustic substance ingestion in children
ConclusionsArtificial intelligence systems have a high potential to be used in the prediction of caustic burns in pediatric age groups. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 13, 2023 Category: Surgery Source Type: research

Letter to the Editor
(Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 13, 2023 Category: Surgery Source Type: research

Association between bacterial resistance profile and the development of intra-abdominal abscesses in pediatric patients with perforated appendicitis: cohort study
ConclusionE. coli was the most commonly isolated microorganism, with a low rate of ESBL-producing isolates. No association between resistance and risk of postoperative intra-abdominal abscess was found. However, it was identified that being a high-risk patient on admission was associated with this complication.Type of studyPrognosis study.Level of evidenceLevel I. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 11, 2023 Category: Surgery Source Type: research

Laparoscopic inguinal hernia repair (LIHR): the benefit of the double stitch in the largest single-center experience
ConclusionThis is the largest single-center reported series of LIHR. LIHR is safe at any age, the risk of recurrence is low, and can be corrected by re-laparoscopy. Use of a Z-stitch or second purse string is associated with a significantly lower rate of recurrence. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 8, 2023 Category: Surgery Source Type: research

Can we preserve the necrotic testis caused by incarcerated inguinal hernia in infants under 3  months?
ConclusionPreserving the necrotic testis may allow it to survive without impacting the contralateral testis. Therefore, a more conservative approach should be considered for orchiectomy when dealing with testicular necrosis caused by incarcerated inguinal hernias in infants. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 2, 2023 Category: Surgery Source Type: research