Surgical outcomes of very-early-onset ulcerative colitis: retrospective comparative study with older pediatric patients
ConclusionWith regard to complications and outcomes, total colectomy for VEO-UC patients and that for older pediatric UC patients is comparable. However, high-output ileostomy and the long duration of CVC placement may pose management challenges. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 7, 2024 Category: Surgery Source Type: research

Outcomes of one-stage feminizing genitoplasty in children with congenital adrenal hyperplasia and severe virilization
ConclusionAdopting our surgical approach of TUM with modified pull-through vaginoplasty has simplified feminizing surgical reconstruction in CAH cases with severe genital atypia and a very high vaginal confluence with short urethral length, yielding adequate introitus with good anatomical and cosmetic appearance and adequate urinary continence outcomes. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 6, 2024 Category: Surgery Source Type: research

Factors affecting neurodevelopmental outcome following surgical necrotising enterocolitis: a systematic review
AbstractSurgically treated necrotising enterocolitis (sNEC) is associated with significantly worse neurodevelopmental outcomes than that seen in premature infants without NEC. We aim to review the association between factors involved in the surgical treatment of NEC and subsequent neurodevelopmental outcomes to identify potential areas for improvement. The PubMed and Embase databases were interrogated for articles reporting neurodevelopmental outcomes in babies treated surgically for NEC using key terms including: “Infant”, “Necrotising enterocolitis”, “Surgical”, “Neurodevelopmental” and “Outcomes”. Th...
Source: Pediatric Surgery International - March 6, 2024 Category: Surgery Source Type: research

Efforts to improve outcomes among neonates with complex intestinal atresia: a single-center low-income country experience
ConclusionIncreased use of BK anastomoses with early enteral nutrition and decreased use of primary anastomosis improves outcomes for neonates with severe JIA in LIC settings. Implementing this surgical approach in LICs may help address the disparities in outcomes for children with JIA. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 6, 2024 Category: Surgery Source Type: research

Innervation pattern of the unclosed detrusor muscle in classic bladder exstrophy: a study of patients with urothelial overexpression of nerve growth factor
ConclusionOverall our results showed an unharmed innervation pattern in this cohort but a lower density of nerve fibers in the detrusor compared to controls. Further studies in patients after successful primary closure are needed to clarify the potential impact of the urothelial overexpression of NGF modulating the innervation pattern in exstrophic bladders. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 5, 2024 Category: Surgery Source Type: research

Regional lymph node evaluation in pediatric conventional melanoma subtype: a single-center 10-year review
ConclusionsPositive SLN status and age at diagnosis were associated with worse DFS in CM patients. Our study did not find any prognostic or therapeutic value in CLND for pediatric melanoma. Further multicenter trials are needed to confirm our single-institution experience.Level of evidenceLevel IV. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 5, 2024 Category: Surgery Source Type: research

Kono-S anastomosis in Crohn ’s disease: initial experience in pediatric patients
ConclusionAccording to our results, Kono-S anastomosis is safe and feasible in pediatric CD patients, with no observed postoperative complications. These findings support the potential benefit of using Kono-S anastomosis as a treatment approach in children with CD. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 5, 2024 Category: Surgery Source Type: research

Innervation pattern of the unclosed detrusor muscle in classic bladder exstrophy: a study of patients with urothelial overexpression of nerve growth factor
ConclusionOverall our results showed an unharmed innervation pattern in this cohort but a lower density of nerve fibers in the detrusor compared to controls. Further studies in patients after successful primary closure are needed to clarify the potential impact of the urothelial overexpression of NGF modulating the innervation pattern in exstrophic bladders. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 5, 2024 Category: Surgery Source Type: research

Regional lymph node evaluation in pediatric conventional melanoma subtype: a single-center 10-year review
ConclusionsPositive SLN status and age at diagnosis were associated with worse DFS in CM patients. Our study did not find any prognostic or therapeutic value in CLND for pediatric melanoma. Further multicenter trials are needed to confirm our single-institution experience.Level of evidenceLevel IV. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 5, 2024 Category: Surgery Source Type: research

Kono-S anastomosis in Crohn ’s disease: initial experience in pediatric patients
ConclusionAccording to our results, Kono-S anastomosis is safe and feasible in pediatric CD patients, with no observed postoperative complications. These findings support the potential benefit of using Kono-S anastomosis as a treatment approach in children with CD. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 5, 2024 Category: Surgery Source Type: research

Delayed diagnosis in Hirschsprung disease
ConclusionsThe results of our study underline that a significant percentage of patients are basically missed in the neonatal period mostly due to mild symptoms. Overall outcome does not differ from that of patients without diagnostic delay. Nonetheless, we underline the importance of a throughout investigation of all patients with meconium delay/failure and that of adopting a low threshold for performing rectal suction biopsies in constipated children to avoid misdiagnosis to serve the best for our patients. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 4, 2024 Category: Surgery Source Type: research

Comorbidities are not associated with pain symptom or recurrence in patients with pilonidal disease
ConclusionsHaving comorbidities was not associated with pain symptoms or recurrence in PD patients. Even though patients with recurrence were younger, there was no association between comorbidity and recurrence in either adolescents or adults. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 4, 2024 Category: Surgery Source Type: research

Delayed diagnosis in Hirschsprung disease
ConclusionsThe results of our study underline that a significant percentage of patients are basically missed in the neonatal period mostly due to mild symptoms. Overall outcome does not differ from that of patients without diagnostic delay. Nonetheless, we underline the importance of a throughout investigation of all patients with meconium delay/failure and that of adopting a low threshold for performing rectal suction biopsies in constipated children to avoid misdiagnosis to serve the best for our patients. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 4, 2024 Category: Surgery Source Type: research

Comorbidities are not associated with pain symptom or recurrence in patients with pilonidal disease
ConclusionsHaving comorbidities was not associated with pain symptoms or recurrence in PD patients. Even though patients with recurrence were younger, there was no association between comorbidity and recurrence in either adolescents or adults. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - March 4, 2024 Category: Surgery Source Type: research

Use of pedicled flaps after oncologic resections in pediatric patients
AbstractThe aim of this study is to review the indications of pedicled flaps and analyze the results.  A observational retrospective study of under 18-year-old oncology patients who required reconstructive surgery with pedicled flaps between 2011 and 2022 was performed. Demographic and clinical variables, indications, complications, and outcomes were collected. 236 patients were reviewed and 13 me t inclusion criteria, eight girls and five boys (mean age: 10.6 years). Indications were Ewing’s sarcoma (5), osteosarcoma (5), neuroblastoma, desmoid tumor, and neurofibroma. Preoperative PET-CT, MRI and bone scintigraphy w...
Source: Pediatric Surgery International - March 3, 2024 Category: Surgery Source Type: research