Management and outcomes of acute appendicitis in children during the COVID-19 pandemic: a systematic review and meta-analysis
AbstractThe COVID-19 pandemic has changed the way to manage the emergencies, as people faced fear of the hospitals, with possible delay in the diagnosis. Moreover, clinicians had to rearrange protocols for diagnosis and treatment. We aimed to assess whether COVID-19 pandemic influenced severity of inflammation, management, and outcomes of acute appendicitis (AA), when compared to the pre-COVID era. Using defined search strategy, two independent investigators identified those studies comparing pediatric AA during COVID-19 pandemicversus the pre-COVID-19 period. Meta-analysis was performed using RevMan 5.3. Data are mean  ...
Source: Pediatric Surgery International - November 28, 2023 Category: Surgery Source Type: research

Application of contrast-enhanced ultrasound in the surgical treatment of vesicoureteral reflux in children
ConclusionCeVUS is an accurate and safe examination, with considerable clinical significance for diagnosing VUR in children, determining the treatment approach, conducting follow-up during treatment, and evaluating subsequent treatment outcomes. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 25, 2023 Category: Surgery Source Type: research

Patent processus vaginalis: role of ultrasound in pediatric population with unilateral inguinal hernia and other predictors
ConclusionsUltrasound has a high accuracy profile and is a useful alternative in limited resource settings with restricted access to minimally invasive surgery for the prediction of CPPV. Patients younger than 1 year with a right-sided hernia or a manifested hernia defect larger than 10 mm are at a higher risk of having a CPPV. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 24, 2023 Category: Surgery Source Type: research

Diaphragmatic hernia repair porcine model to compare the performance of biodegradable membranes against Gore-Tex ®
ConclusionGore-Tex® was associated with a higher survival rate and lower recurrence. Nevertheless, the proposed biodegradable membranes were associated with better tissue integration when compared with Gore-Tex®. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 24, 2023 Category: Surgery Source Type: research

Generation of human gastric assembloids from primary fetal organoids
ConclusionsfGOs can reliably be generated from human fetal samples. This pioneering assembloid approach paves the way  for advancing our comprehension of human gastric epithelium homeostasis and its perturbation, offering a better in vitro platform for the study of gastric epithelial development and therapeutic translation. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 24, 2023 Category: Surgery Source Type: research

Potential mechanisms underlying the effect of hepatocyte growth factor on liver injury in short bowel syndrome model rats
ConclusionThe inhibitory effect of HGF on hepatic steatosis remains unclear, and further studies focusing on the mechanisms of fat accumulation are needed. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 24, 2023 Category: Surgery Source Type: research

Patent processus vaginalis: role of ultrasound in pediatric population with unilateral inguinal hernia and other predictors
ConclusionsUltrasound has a high accuracy profile and is a useful alternative in limited resource settings with restricted access to minimally invasive surgery for the prediction of CPPV. Patients younger than 1 year with a right-sided hernia or a manifested hernia defect larger than 10 mm are at a higher risk of having a CPPV. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 24, 2023 Category: Surgery Source Type: research

Diaphragmatic hernia repair porcine model to compare the performance of biodegradable membranes against Gore-Tex ®
ConclusionGore-Tex® was associated with a higher survival rate and lower recurrence. Nevertheless, the proposed biodegradable membranes were associated with better tissue integration when compared with Gore-Tex®. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 24, 2023 Category: Surgery Source Type: research

Generation of human gastric assembloids from primary fetal organoids
ConclusionsfGOs can reliably be generated from human fetal samples. This pioneering assembloid approach paves the way  for advancing our comprehension of human gastric epithelium homeostasis and its perturbation, offering a better in vitro platform for the study of gastric epithelial development and therapeutic translation. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 24, 2023 Category: Surgery Source Type: research

Potential mechanisms underlying the effect of hepatocyte growth factor on liver injury in short bowel syndrome model rats
ConclusionThe inhibitory effect of HGF on hepatic steatosis remains unclear, and further studies focusing on the mechanisms of fat accumulation are needed. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 24, 2023 Category: Surgery Source Type: research

Premalignant/malignant histology in excised choledochal cyst specimens from children. Experience and literature review
ConclusionsThe present study identified the youngest cases of AIS and dysplasia from specimens excised when they were 3  years old and 4 months old, respectively. Both are published for the first time as evidence that PMMH can complicate CC in young patients. Long-term protocolized postoperative follow-up is mandatory when PMMH is diagnosed in pediatric CC. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 23, 2023 Category: Surgery Source Type: research