DraiNet: AI-driven decision support in pneumothorax and pleural effusion management
ConclusionThe integration of DraiNet as an AI-driven decision support system marks a significant advancement in pediatric healthcare. By combining deep learning algorithms with clinical expertise, DraiNet provides a valuable tool for non-surgical teams and emergency room doctors, aiding them in making informed decisions about surgical interventions. With its remarkable mAP score of 0.964, DraiNet has the potential to enhance patient outcomes and optimize the management of critical conditions, including pneumothorax and pleural effusion. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 27, 2023 Category: Surgery Source Type: research

Efficacy and late kidney effects of nephron-sparing surgery in the management of unilateral Wilms tumor: a systematic review and meta-analysis
AbstractTo evaluate the efficiency and long-term renal function of nephron sparing surgery (NSS) in unilateral WT patients compared with radical nephrectomy (RN). The review was performed following Cochrane Handbook guidelines and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). We searched five databases (Pubmed, Embase, Scopus, Web of Science and Cochrane) for studies reporting the efficiency and late renal function of NSS and/or RN on February 10, 2023. Comparative studies were evaluated by Risk of Bias in Non-randomized Studies of Interventions (ROBINS-I) and RoB 2.0. Assessed outcomes inclu...
Source: Pediatric Surgery International - December 27, 2023 Category: Surgery Source Type: research

Development of a 3D-printed neonatal congenital diaphragmatic hernia model and standardisation of intra-operative measurement
ConclusionsWe have designed and built simulation models for CDH repair via laparotomy and thoracoscopically. Operators can reliably measure the diaphragmatic defect and ipsilateral diaphragm, regardless of surgical experience and operative approach. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 26, 2023 Category: Surgery Source Type: research

Commentary on “Laparoscopic inguinal hernia repair (LIHR): the benefit of the double stitch in the largest single-center experience”
(Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 23, 2023 Category: Surgery Source Type: research

Correlation analysis of feeding intolerance and defecation after primary anastomosis for neonatal intestinal atresia
ConclusionThe incidence of postoperative feeding intolerance is higher in preterm infants, and pediatricians can decide the timing of breastfeeding on the basis of the patients ’ defecation. The focus on accurate defecation may be more meaningful in determining and predicting postoperative feeding intolerance in the infants. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 22, 2023 Category: Surgery Source Type: research

Diagnostic and prognostic value of the gut microbiota and its metabolite butyrate in children with biliary atresia
ConclusionsOur study reveals changes in the composition of the gut microbiota in BA, especially the butyrate-producing microbiota, and suggests the potential for using gut microbiota as a noninvasive diagnostic benefit for BA. Low levels of serum butyrate in BA may indicate a poor prognosis. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 21, 2023 Category: Surgery Source Type: research

Circular RNA MTCL1 targets SMAD3 by sponging miR-145 ‐5p for regulation of cell proliferation and migration in Hirschsprung’s disease
ConclusionsCirc-MTCL1 may function as a miR-145-5p sponge, regulating the expression of SMAD3 and influencing cell migration and proliferation, thus participating in the development of HSCR. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 21, 2023 Category: Surgery Source Type: research

The mechanism of intestinal stem cells differentiation after ischemia –reperfusion injury in a rat model
ConclusionsIntestinal stem-cell differentiation is toward secretory cells 48  h after IR injury; however, Wnt/β-catenin pathway inhibition and Notch-related gene expression stimulation suggest crosstalk between pathways. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

Rectal biopsy: is it really necessary in anorectal malformations?
ConclusionsOur results strongly suggest that the association of ARM and HD is extremely rare and the practice of searching for ganglia in the distal rectum or fistula of ARM patients should be discouraged to avoid potential misdiagnosis and overtreatment. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

The mechanism of intestinal stem cells differentiation after ischemia –reperfusion injury in a rat model
ConclusionsIntestinal stem-cell differentiation is toward secretory cells 48  h after IR injury; however, Wnt/β-catenin pathway inhibition and Notch-related gene expression stimulation suggest crosstalk between pathways. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

Argon inhalation attenuates systemic inflammation and rescues lung architecture during experimental neonatal sepsis
ConclusionsOur findings suggest that argon inhalation as a novel treatment for neonatal sepsis, reducing mortality and counteracting the acute systemic inflammatory response in the blood and preserving the architecture of the lung. This research can contribute to a paradigm shift in the treatment and outcome of neonates with sepsis. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

Rectal biopsy: is it really necessary in anorectal malformations?
ConclusionsOur results strongly suggest that the association of ARM and HD is extremely rare and the practice of searching for ganglia in the distal rectum or fistula of ARM patients should be discouraged to avoid potential misdiagnosis and overtreatment. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

Argon inhalation attenuates systemic inflammation and rescues lung architecture during experimental neonatal sepsis
ConclusionsOur findings suggest that argon inhalation as a novel treatment for neonatal sepsis, reducing mortality and counteracting the acute systemic inflammatory response in the blood and preserving the architecture of the lung. This research can contribute to a paradigm shift in the treatment and outcome of neonates with sepsis. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 18, 2023 Category: Surgery Source Type: research

A simple machine learning approach for preoperative diagnosis of esophageal burns after caustic substance ingestion in children
ConclusionsArtificial intelligence systems have a high potential to be used in the prediction of caustic burns in pediatric age groups. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 13, 2023 Category: Surgery Source Type: research

Letter to the Editor
(Source: Pediatric Surgery International)
Source: Pediatric Surgery International - December 13, 2023 Category: Surgery Source Type: research