Neurodevelopmental impairment following surgical necrotizing enterocolitis with gestational age  ≥ 28 weeks: who is at risk?

ConclusionsOur study identified gestational age  ≤ 32 weeks, assisted mechanical ventilation after NEC onset, postoperative acute kidney injury, CRP day 3 after NEC onset, and time from presentation to surgery as significant risk factors for NDI in neonates with surgical NEC. These factors would be helpful to refine treatment modalities fo r better disease outcomes. We also determined the cut-off values of CRP day 3 after NEC onset and time from presentation to surgery, allowing for the individualized evaluation of NDI risk and the implementation of earlier targeted laparotomy.
Source: Pediatric Surgery International - Category: Surgery Source Type: research