Advances in pediatric liver transplantation from the pediatric surgeon ’s perspective
AbstractPediatric liver transplantation is a lifesaving state-of-the-art operation for children with various liver diseases, including cholestatic diseases, metabolic disorders, acute liver failure, and primary malignant liver tumors. Among these indications, transplantation for biliary atresia and hepatoblastoma is discussed in this review because pediatric surgeons are usually involved in their initial treatments. For biliary atresia, pediatric surgeons are advised to keep dissection of the hilar structures to a minimum during Kasai portoenterostomy in order to make total hepatectomy easier at transplantation. Early refe...
Source: Pediatric Surgery International - August 25, 2023 Category: Surgery Source Type: research

Downregulation of miR-144 blocked the proliferation and invasion of nerve cells in Hirschsprung disease by regulating Transcription Factor AP 4 (TFAP4)
ConclusionsDownregulation of miR-144 blocked the cell proliferation and migration of nerve cells via targeting TFAP4 and contributed to the pathogenesis of HSCR. This provides an innovative and candidate target for treatment of HSCR. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - August 23, 2023 Category: Surgery Source Type: research

Fecal calprotectin as a non-invasive marker for the prediction of post-necrotizing enterocolitis stricture
ConclusionAs a non-invasive parameter, FC has excellent efficacy and accuracy in predicting post-NEC intestinal stricture. Increased FC levels at the acute phase of NEC were associated with the development of intestinal stricture. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - August 18, 2023 Category: Surgery Source Type: research

Does the distal ureteral diameter ratio (UDR) matter in the surgical management of vesicoureteral reflux in children?
ConclusionUDR shows to be a more reliable measurement that allows for an objective estimation of VUR severity and prognosis. It represents a quantitative parameter that might be useful to identify patients who may benefit endoscopic or surgical treatment, avoiding unnecessary under or over-treatment. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - August 17, 2023 Category: Surgery Source Type: research

Gastroschisis in Sub-Saharan Africa: a scoping review of the prevalence, management practices, and associated outcomes
AbstractGastroschisis is a congenital defect of the anterior abdominal wall characterized by a periumbilical abdominal wall defect with associated bowel protrusion. Limitations in the diagnosis and management of gastroschisis in Sub-Saharan African countries contribute to the high mortality rate. Few studies have been published despite its significant contribution to neonatal mortality in Sub-Saharan Africa. This review study explores the prevalence of gastroschisis, likewise the management and clinical outcomes. Full-text articles reporting the prevalence, management, and associated outcomes of gastroschisis in Sub-Sahara...
Source: Pediatric Surgery International - August 16, 2023 Category: Surgery Source Type: research

Thromboprophylaxis in pediatric patients with earthquake-related crush syndrome: a single centre experience
ConclusionWith the decision-making algorithm for thyromboprophylaxis we used, we observed a VTE rate of 2.1% in pediatric patients with earthquake-related crush syndrome. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - August 16, 2023 Category: Surgery Source Type: research

Long-term urological outcome of cloaca patients with multidisciplinary management
ConclusionsLength of CC and OSD may affect urinary and fecal continence. An early counseling can improve outcome at long-term follow-up. Multidisciplinary management with patient centralization in high grade institutions is recommended to achieve better results. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - August 16, 2023 Category: Surgery Source Type: research

Gastroschisis in Sub-Saharan Africa: a scoping review of the prevalence, management practices, and associated outcomes
AbstractGastroschisis is a congenital defect of the anterior abdominal wall characterized by a periumbilical abdominal wall defect with associated bowel protrusion. Limitations in the diagnosis and management of gastroschisis in Sub-Saharan African countries contribute to the high mortality rate. Few studies have been published despite its significant contribution to neonatal mortality in Sub-Saharan Africa. This review study explores the prevalence of gastroschisis, likewise the management and clinical outcomes. Full-text articles reporting the prevalence, management, and associated outcomes of gastroschisis in Sub-Sahara...
Source: Pediatric Surgery International - August 16, 2023 Category: Surgery Source Type: research

Thromboprophylaxis in pediatric patients with earthquake-related crush syndrome: a single centre experience
ConclusionWith the decision-making algorithm for thyromboprophylaxis we used, we observed a VTE rate of 2.1% in pediatric patients with earthquake-related crush syndrome. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - August 16, 2023 Category: Surgery Source Type: research

Long-term urological outcome of cloaca patients with multidisciplinary management
ConclusionsLength of CC and OSD may affect urinary and fecal continence. An early counseling can improve outcome at long-term follow-up. Multidisciplinary management with patient centralization in high grade institutions is recommended to achieve better results. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - August 16, 2023 Category: Surgery Source Type: research

The role of distance between upper and lower esophageal pouches to predict the possibility of delayed repair in children with isolated esophageal atresia
ConclusionBoth upper and lower pouch lengths were shorter in ER group compared to DPR group. However, pouch lengths cannot be considered as a single criterion to predict the need for ER. Large cohort of patients are needed to define the cut-off values for shortest pouch length to achieve a DPR. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - July 31, 2023 Category: Surgery Source Type: research