The impact of the recipient intestinal site on the differentiation of transplanted enteric neural crest cells
ConclusionOur study highlights the differences in ENCC differentiation depending on the site of transplantation. To further develop cell therapy for HD, it is important to consider the impact of the recipient intestinal environment on transplanted ENCCs. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 20, 2023 Category: Surgery Source Type: research

The evidence mismatch in pediatric surgical practice
ConclusionsPublished literature concerning common outpatient pediatric surgical conditions is sparse and demonstrates wide variations in practice. All individual practice choices were justified using either risk of complications or patient preference. Most early intervention practices were based on weak or outdated studies and “common wisdom” rather than genuine evidence.Level of evidenceIII. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 18, 2023 Category: Surgery Source Type: research

Mortality and neurodevelopmental outcomes in very low birth weight infants with esophageal atresia
ConclusionsIn VLBWIs with EA, survival discharge from NICU was still not high. More immature patients and patients with an associated anomaly had worse outcomes. Among patients who survived, NDI was confirmed in a certain number of patients. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 17, 2023 Category: Surgery Source Type: research

Fetal ascites in cloacal malformations —a red flag
ConclusionsAntenatal finding of ascites in newborns with cloacal malformations should raise a red flag. The surgeon and anaesthetist should be prepared for the operative difficulties secondary to bowel adhesions and the higher risk of haemodynamic instability at the initial surgery. An experienced team at initial laparotomy in such patients is vital.Level of evidence: II. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 16, 2023 Category: Surgery Source Type: research

Pilot bowel management program at Mbarara Hospital, Uganda
ConclusionsWe describe the first BMP in Uganda. BMPs can successfully treat constipation and fecal incontinence in low-income countries, although there are challenges with resources and follow-up. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 14, 2023 Category: Surgery Source Type: research

Anti-inflammatory effects of antenatal administration of stem cell derived  extracellular vesicles in the brain of rat fetuses with congenital diaphragmatic hernia
ConclusionThis study shows that the brain of rat fetuses with CDH has signs of inflammation that are abated by the intra-amniotic administration of AFSC-EVs. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 13, 2023 Category: Surgery Source Type: research

Use of the Kono-S anastomosis in pediatric Crohn ’s disease: a single-institution experience
ConclusionThe Kono-S anastomosis appears to be safe in pediatric CD when compared to traditional stapled anastomoses. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 10, 2023 Category: Surgery Source Type: research

Surgical approach to penile reconstruction for shaft skin excision from circumcision
(Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 7, 2023 Category: Surgery Source Type: research

Correction to: Flow cytometric characterization of cecal appendix lymphocyte subpopulations in children: a pilot study
(Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 7, 2023 Category: Surgery Source Type: research

Surgical approach to penile reconstruction for shaft skin excision from circumcision
(Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 7, 2023 Category: Surgery Source Type: research

Pleural drainage vs video-assisted thoracoscopic debridement in children affected by pleural empyema
ConclusionsVATS is an effective and safe procedure in treatment of Pleural Empyema in children: it is associated to reduction of chest tube drainage, duration of fever, hospital stay, time of antibiotic therapy and recurrence rate. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 6, 2023 Category: Surgery Source Type: research

The advantages of duct-to-duct biliary reconstruction in pediatric living donor liver transplantation
ConclusionWith a proper selection of cases, DD should be a safe method for biliary reconstruction in pediatric recipients with little risk of biliary complications equivalent to HJ and a reduced risk of intestinal complications. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - November 2, 2023 Category: Surgery Source Type: research