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[ASAP] Efficient Kilogram-Scale Synthesis of a Novel Oxazolidinone Antibacterial Candidate < bold > YG-056SP < /bold >
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00350 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 20, 2023 Category: Chemistry Authors: Yinyong Zhang, Yushe Yang, Xin Meng, Xianli Zhou, and Bin Guo Source Type: research

[ASAP] Synthesis of a Pyridoazepine Scaffold via Rhodium-Catalyzed Ring Expansion and Nitroacetamide Condensation
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00145 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 17, 2023 Category: Chemistry Authors: Eddie Yang, Joseph W. Tucker, Thomas A. Chappie, John D. Weaver, Caroline Chapman ¥, Remzi Duzguner, and John M. Humphrey Source Type: research

[ASAP] Generation of 1,2-Difluorobenzene via a Photochemical Fluorodediazoniation Step in a Continuous Flow Mode
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00348 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 16, 2023 Category: Chemistry Authors: Kevin Simon, Desiree Znidar, Julien Boutet, Ge ́rard Guillamot, Jean-Yves Lenoir, Doris Dallinger, and C. Oliver Kappe Source Type: research

[ASAP] Continuous Flow Epoxidation of Alkenes Using a Homogeneous Manganese Catalyst with Peracetic Acid
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00222 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 14, 2023 Category: Chemistry Authors: Ailbhe A. Ryan, Sea ́n D. Dempsey, Megan Smyth, Karen Fahey, Thomas S. Moody, Scott Wharry, Paul Dingwall, David W. Rooney, Jillian M. Thompson, Peter C. Knipe, and Mark J. Muldoon Source Type: research

[ASAP] Process Intensification and Increased Safety for the On-Demand Continuous Flow Synthesis of Dithiothreitol, a Crucial Component in Polymerase Chain Reaction Testing Kits
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00345 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 11, 2023 Category: Chemistry Authors: Maryne A. J. Dubois, Virginie Carreras, Matt R. Adams, Vanessa Kairouz, Jean-Franc ̧ois Vincent-Rocan, John G. Riley, and André B. Charette Source Type: research

[ASAP] Transformation of the Manufacturing Process from Discovery to Kilogram Scale for AWZ1066S: A Highly Specific Anti- < italic toggle="yes" > Wolbachia < /italic > Drug Candidate for a Short-Course Treatment of Filariasis
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00167 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 10, 2023 Category: Chemistry Authors: W. David Hong, Paul M. O ’Neill, Mark J. Taylor, Joseph D. Turner, Stephen A. Ward, Fabian Gusovsky, Farid Benayoud, Nao Shibuguchi, Dixit Girish, Francis Gerard Fang, Ravi Kumar Talabhakthla, Anand Vaddi, Chiranjeevi Challa, Karri Satya Ammi Reddy, Vij Source Type: research

[ASAP] A Cobalt-Containing Polysilane as an Effective Solid-State Catalyst for the Hydrosilylation of Alkenes
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00279 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 9, 2023 Category: Chemistry Authors: Tatsuyoshi Ito and Yusuke Sunada Source Type: research

[ASAP] Some Items of Interest to Process R & D Chemists and Engineers
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00393 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 9, 2023 Category: Chemistry Authors: Alan Steven, Robert B. Kargbo, Carlos Mateos, Andrei A. Zlota, Christopher C. Nawrat, James P. Phelan, Alexandre Barthelme, Sylvain Guizzetti, and John Knight Source Type: research

[ASAP] Expeditious Synthesis of a Potent Allosteric HIV ‑1 Integrase Inhibitor GSK3839919A
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00343 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 9, 2023 Category: Chemistry Authors: Mark A. Bobko, Jennifer M. Elward, B. Narasimhulu Naidu, Yexenia E. Nieves-Quinones, Christopher A. Reiher, Qiaogong Su, Liang Sun, John Woodard, Shiping Xie, Wuxing Yang, and Yunxing Yin Source Type: research

[ASAP] Tracking the Isotopologues: Process Improvement for the Synthesis of a Deuterated Pyrazole
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00318 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 6, 2023 Category: Chemistry Authors: Zachary J. Garlets, Elizabeth M. Yuill, Alice Yang, Qingmei Ye, Wei Ding, Christopher Wood, Junying Fan, Nicolas Lucien Cuniere, and Chris Sfouggatakis Source Type: research

[ASAP] Impurity Purging through Systematic Process Development of a Continuous Two-Stage Crystallization
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00317 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 4, 2023 Category: Chemistry Authors: Drew Scott, Naomi E. B. Briggs, Anna Formosa, Annessa Burnett, Bimbisar Desai, Greg Hammersmith, Kersten Rapp, Gerard Capellades, Allan S. Myerson, and Thomas D. Roper Source Type: research

[ASAP] Development of a Novel Process for the Preparation of the Anti-Inflammatory Drug Betamethasone Sodium Phosphate
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00329 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - January 3, 2023 Category: Chemistry Authors: Antonio Bova, Manuela Saba, Stefano Novelli, and Fabio Pecora Source Type: research

[ASAP] Control of Hydrogen Fluoride Formation and Release during a Large-Scale Nitroarene Reduction in the Manufacture of AZD9977
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00323 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - December 28, 2022 Category: Chemistry Authors: Carl J. Mallia, Joe ̈l Le Bars, Simon Hardy, Alex Lamacraft, Simon Harding, David Hose, Lindsay Snow, Rebecca C. Poulten, Benjamin C. Dobson, Trevor Churchill, and Paul M. Gillespie Source Type: research

[ASAP] Hindered Biaryl Bond Construction and Subsequent Diastereomeric Crystallization to Produce an Atropisomeric Covalent KRAS < sup > G12C < /sup > Inhibitor ARS-2102
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00335 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - December 28, 2022 Category: Chemistry Authors: Xiaogen Yang, Zhiwen Li, Wenwen Xu, Guanming Zhu, Xiantong Feng, Jun Zhang, Hongbin Zhao, Yuyin Chen, Jianshe Kong, Wanping Mai, Lian-Sheng Li, Daniel J. Pippel, Pingda Ren, and Xiaohu Deng Source Type: research

[ASAP] Nitrosamine Risk Assessments in Oligonucleotides
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00330 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - December 26, 2022 Category: Chemistry Authors: Christopher J. Borths, Tracey Burr, Aude Figuccia, J. Gair Ford, Bing Guan, Michael T. Jones, Didier Klingeleers, Susanne Lochner, Andrew A. Rodriguez, and Christian Wetter Source Type: research