[ASAP] Hindered Biaryl Bond Construction and Subsequent Diastereomeric Crystallization to Produce an Atropisomeric Covalent KRAS < sup > G12C < /sup > Inhibitor ARS-2102

Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00335

Source: Organic Process Research and Development - December 28, 2022 Category: Chemistry Authors: Xiaogen Yang, Zhiwen Li, Wenwen Xu, Guanming Zhu, Xiantong Feng, Jun Zhang, Hongbin Zhao, Yuyin Chen, Jianshe Kong, Wanping Mai, Lian-Sheng Li, Daniel J. Pippel, Pingda Ren, and Xiaohu Deng Source Type: research