Organic Process Research and Development 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.[ASAP] Advancing Scalable Chemistry toward Novel CELMoDs: Process Development for the Synthesis of CC-90009
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00199 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - September 1, 2022 Category: Chemistry Authors: Michael J. Zacuto, Michael J. Williams, Weihong Zhang, Jianxin Han, Marie G. Beauchamps, Mohit Kothare, William Konnecke, Randi Smith, and Gregg Feigelson Source Type: research
[ASAP] Regulatory Highlights
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00257 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 31, 2022 Category: Chemistry Authors: Andrew Teasdale and Matthew Popkin Source Type: research
[ASAP] Streamlined Synthesis of Aminoacridinium Photocatalysts with Improved Photostability
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00209 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 31, 2022 Category: Chemistry Authors: Markus Jakobi and Christof Sparr Source Type: research
[ASAP] Antibody –Drug Conjugate Synthesis Using Continuous Flow Microreactor Technology
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00217 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 31, 2022 Category: Chemistry Authors: Yuichi Nakahara, Brian A. Mendelsohn, and Yutaka Matsuda Source Type: research
[ASAP] Rate of Formation of Industrial Lubricant Additive Precursors from Maleic Anhydride and Polyisobutylene
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00207 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 30, 2022 Category: Chemistry Authors: Jessica Streets, Nicolas Proust, Dixit Parmar, Gary Walker, Peter Licence, and Simon Woodward Source Type: research
[ASAP] Efficient and Improved Solution-Phase Synthesis of Modified RNA Dinucleotides: Versatile Synthons in Cap 1 mRNA Therapeutics
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00218 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 25, 2022 Category: Chemistry Authors: Annamalai Senthilvelan, Muthian Shanmugasundaram, and Anilkumar R. Kore Source Type: research
[ASAP] Novel Analytical Approach to Quantify Reactive Potentially Mutagenic Sulfonate Ester Impurities in Pharmaceutical Compounds and Its Application in the Development of a Control Strategy for Nonaflate Impurities in Belzutifan Synthesis
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00182 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 24, 2022 Category: Chemistry Authors: Rekha Gangam, Wenjun Liu, Michael T. Pirnot, Stephen M. Dalby, Adam J. Fine, and Brittany Kassim Source Type: research
[ASAP] High-Productivity Single-Pass Electrochemical Birch Reduction of Naphthalenes in a Continuous Flow Electrochemical Taylor Vortex Reactor
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00108 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 24, 2022 Category: Chemistry Authors: Darren S. Lee, Ashley Love, Zakaria Mansouri, Toby H. Waldron Clarke, David C. Harrowven, Richard Jefferson-Loveday, Stephen J. Pickering, Martyn Poliakoff, and Michael W. George Source Type: research
[ASAP] Axial Chirality in the Sotorasib Drug Substance, Part 1: Development of a Classical Resolution to Prepare an Atropisomerically Pure Sotorasib Intermediate
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00176 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 23, 2022 Category: Chemistry Authors: Andrew T. Parsons, Seb Caille, Marc A. Caporini, Daniel J. Griffin, Michael A. Lovette, William Powazinik, IV, and Gabrielle St-Pierre Source Type: research
[ASAP] Axial Chirality in the Sotorasib Drug Substance, Part 2: Leveraging a High-Temperature Thermal Racemization to Recycle the Classical Resolution Waste Stream
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00177 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 23, 2022 Category: Chemistry Authors: Matthew G. Beaver, Derek B. Brown, Kiersten Campbell, Yuan-Qing Fang, David D. Ford, Narbe Mardirossian, Kevin D. Nagy, Andreas R. Ro ̈theli, Jillian W. Sheeran, Reem Telmesani, and Andrew T. Parsons Source Type: research
[ASAP] Continuous and Safe Alkylation of 1,3,5-Trihydroxy-2,4,6-trinitrobenzene using Wiped Film Evaporator/Distillation Coupled Technology
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00105 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 22, 2022 Category: Chemistry Authors: Xingyu Shao, Wei Feng, Zichao Guo, and Wanghua Chen Source Type: research
[ASAP] Process Development and Scale-Up of a Protease Inhibitor for the Treatment of HIV Featuring the Preparation of a Neopentyl Grignard Reagent and Development of a One-Pot Curtius Reaction
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00153 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 18, 2022 Category: Chemistry Authors: Michael A. Ischay, Brittanie Hoang, Dietrich P. Steinhuebel, Matthew R. Chin, Darryl D. Dixon, Danielle Elfgren, Lars Heumann, Willard Lew, Devon A. Mundal, Sean T. Neville, Nisha P. Shah, Bing Shi, Jonathan C. Tripp, and Queenie Wang Source Type: research
[ASAP] Use of Phosphazene Base BTPP for Phosphorylative Activation in the Scale-Up of BET Inhibitor GSK525762
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00048 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 18, 2022 Category: Chemistry Authors: Rhiannon E. H. Jones, Peter Aspin, Suzanne H. Davies, Inderjit Mann, Catherine Priestley, Andrew D. Roberts, Natalia Zotova-Eldridge, and John H. Leahy Source Type: research
[ASAP] Continuous-Flow Synthesis of < italic toggle="yes" > syn < /italic > -2-Amino-1,3-diol via Catalytic Hydrogenation: A Vital Intermediate of (+)-Thiamphenicol and (+)-Florfenicol
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00100 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 17, 2022 Category: Chemistry Authors: Yingqi Xia, Baijun Ye, Minjie Liu, Meifen Jiang, and Fener Chen Source Type: research
[ASAP] Manufacturing Process Development for Uprifosbuvir (MK-3682): A Green and Sustainable Process for Preparing Penultimate 2 ′-Deoxy-α-2′-Chloro-β-2′-Methyluridine
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00191 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - August 16, 2022 Category: Chemistry Authors: Peter E. Maligres, Feng Peng, Ralph Calabria, Louis-Charles Campeau, Wenyong Chen, Peter G. Dormer, Meredith Green, Cyndi Qixin He, Alan M. Hyde, Artis Klapars, Mona Utne Larsen, John Limanto, Guiquan Liu, Yizhou Liu, Aaron Moment, Timothy Nowak, Rebecca Source Type: research
