[ASAP] Recent Advances in the Solid- and Solution-Phase Synthesis of Peptides and Proteins Using Microflow Technology
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00074 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 27, 2022 Category: Chemistry Authors: Hisashi Masui and Shinichiro Fuse Source Type: research

[ASAP] Multigram Scale Synthesis of Piperarborenines C ‑E
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00049 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 26, 2022 Category: Chemistry Authors: Jason M. Lenihan, Matthew J. Mailloux, and Aaron B. Beeler Source Type: research

[ASAP] Correction to “Thermal Instability and Associated Potential Safety Hazards of Rhodium(I) Precatalyst Complexes with Weakly Coordinated Ligands”
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00133 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 25, 2022 Category: Chemistry Authors: Min Sheng, Qiang Yang, Darren Huff, Andrew G. Schafer, Craig Tucker, and Daniel Valco Source Type: research

[ASAP] Cu-Mediated Ullmann-Type Cross-Coupling and Industrial Applications in Route Design, Process Development, and Scale-up of Pharmaceutical and Agrochemical Processes
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00050 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 24, 2022 Category: Chemistry Authors: Qiang Yang, Yinsong Zhao, and Dawei Ma Source Type: research

[ASAP] Enantioselective Synthesis of the Chiral Pyrrolidine Fragment of Upadacitinib < italic toggle="yes" > via < /italic > Chiral Auxiliary Directed Diastereoselective 1,3-Dipolar Cycloaddition
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.1c00454 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 20, 2022 Category: Chemistry Authors: Magesh Sampath, Sembian Ruso Jayaraman, Vishnuvardhan Reddy Eda, Rajendar Potham, Rajeev Rehani Budhdev, Saikat Sen, Rakeshwar Bandichhor, and Srinivas Oruganti Source Type: research

[ASAP] Discovery and Process Development of a Scalable Biocatalytic Kinetic Resolution toward Synthesis of a Sterically Hindered Chiral Ketone
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00067 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 17, 2022 Category: Chemistry Authors: Nicole Wamser, Hao Wu, Frederic Buono, Anthony Brundage, Francesco Ricci, Jon C. Lorenz, Jun Wang, Nizar Haddad, Joshua Paolillo, Joyce C. Leung, Heewon Lee, and Azad Hossain Source Type: research

[ASAP] Synthesis of 5 ‑Nitrotetrazolate via the Aqueous Oxidation of 5‑Aminotetrazole
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.1c00361 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 11, 2022 Category: Chemistry Authors: Jake E. Zuckerman, Tim D. Manship, Dawson M. Smith, and Davin G. Piercey Source Type: research

[ASAP] Integration of Liquid –Liquid Biphasic Flow Alkylation and Continuous Crystallization Using Taylor Vortex Flow Reactors
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00088 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 10, 2022 Category: Chemistry Authors: Masahiro Hosoya, Masashi Tanaka, Atsushi Manaka, Shogo Nishijima, and Naoki Tsuno Source Type: research

[ASAP] Fit-for-Purpose Synthesis of an Aza-Cryptophycin Analogue as the Payload for an Antibody –Drug Conjugate
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00080 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 10, 2022 Category: Chemistry Authors: Audrey Bendelac, Franc ̧oise Benedetti, Valerie Doublet-Decabras, Rachel Lokovi, François Decalogne, and Antony Bigot Source Type: research

[ASAP] Some Items of Interest to Process R & D Chemists and Engineers
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00118 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 10, 2022 Category: Chemistry Authors: Andrei A. Zlota, Paul F. Richardson, Alan Steven, Robert B. Kargbo, Carlos Mateos, James P. Phelan, Rik Oost, and John Knight Source Type: research

[ASAP] Highly Enantioselective Hydroxylation of 3 ‑Arylpropanenitriles to Access Chiral β‑Hydroxy Nitriles by Engineering of P450pyr Monooxygenase
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.1c00444 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 10, 2022 Category: Chemistry Authors: Guo-Zhong Deng, Xu Zhou, Quan-Xiang Yu, Xue-Qing Mou, Miao An, Hai-Bo Cui, Xiao-Jian Zhou, Nan-Wei Wan, Zhi Li, and Yong-Zheng Chen Source Type: research

[ASAP] Manufacturable Process of a Novel EGFR Inhibitor (Larotinib) for the Treatment of ESCC
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00059 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 9, 2022 Category: Chemistry Authors: Weihong Zhang, Zhiming Su, Haiwang Liu, Yingjun Zhang, Weiliang Ye, Dahua Peng, Hongpeng Xie, Hongtao Peng, Zhihong Peng, Wanrong Dong, and Delie An Source Type: research

[ASAP] Missing Link: Enabling Loading of 2 ‑Chlorotrityl Chloride Resin in < italic toggle="yes" > N < /italic > ‑Butylpyrrolidinone as a Green Solvent
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00052 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 5, 2022 Category: Chemistry Authors: John Lopez, Janina Beck, Christoph Bucher, Arne Berthelmann, Spyridon Markos, and Stefan Eissler Source Type: research

[ASAP] Side-Chain Unprotected Fmoc-Arg/His/Tyr-OH Couplings and Their Application in Solid-Phase Peptide Synthesis through a Minimal-Protection/Green Chemistry Strategy
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.2c00083 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 4, 2022 Category: Chemistry Authors: Yi Yang, Lena Hansen, and Per Ryberg Source Type: research

[ASAP] Optimization of Metal Affinity Ketoreductase Immobilization for Application in Batch and Flow Processes
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.1c00483 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 4, 2022 Category: Chemistry Authors: Alessandra Basso, Maria S. Brown, Alvaro Cruz-Izquierdo, Carlos A. Martinez, and Simona Serban Source Type: research