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[ASAP] Precise Control of the Oxidation Reaction in a High-Purity Dexlansoprazole Synthesis Process Using < italic toggle="yes" > In Situ < /italic > Infrared
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00098 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 27, 2023 Category: Chemistry Authors: Chunchao Wang, Haoyu Wang, Cheng Huang, Chengjun Wu, and Tiemin Sun Source Type: research

[ASAP] Scalable Synthesis of the Shelf-Stable Radical Difluoromethylthiolation Reagent < italic toggle="yes" > S < /italic > ‑(Difluoromethyl)benzenesulfonothioate PhSO < sub > 2 < /sub > SCF < sub > 2 < /sub > H
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00087 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 24, 2023 Category: Chemistry Authors: Xin Qiu, Wenrun Lou, Shengxue Zhang, Shengyajun Meng, Yong Guo, Xiaoyu Ma, Chao Liu, and Qilong Shen Source Type: research

[ASAP] Process Development and Scale-Up of the SOS1 Inhibitor MRTX0902
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00030 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 22, 2023 Category: Chemistry Authors: Thomas Scattolin, Joseph R. Lizza, Zhiliang Xu, Dan Zhao, and Cheng-yi Chen Source Type: research

[ASAP] New Bench-Scale Method To Elucidate Active Pharmaceutical Ingredient Drying Mechanisms
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00066 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 19, 2023 Category: Chemistry Authors: David J. Lamberto, Eric Sirota, and George Zhou Source Type: research

[ASAP] Practical Synthesis of Tenofovir Alafenamide Fumarate Inspired by New Retrosynthetic Disconnection Featuring a Novel Carbon –Phosphorus Bond Construction Methodology
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00070 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 19, 2023 Category: Chemistry Authors: Xiuping Liu, Chen Chen, Muzi Li, Man Li, Jie Ren, and Qingwen Zhang Source Type: research

[ASAP] Effect of Nitrogen, Air, and Oxygen on the Kinetic Stability of NAD(P)H Oxidase Exposed to a Gas –Liquid Interface
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00095 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 19, 2023 Category: Chemistry Authors: Jingyu Wang, Elif Erdem, and John M. Woodley Source Type: research

[ASAP] Scalable Electrochemical Reduction of Nitrobenzotrifluorides to 3 ‑Trifluoromethylanilines
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00067 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 12, 2023 Category: Chemistry Authors: Camila M. Kisukuri, Johannes Seidler, Tobias Ga ̈rtner, Denis F. Rohrmann, and Siegfried R. Waldvogel Source Type: research

[ASAP] First-Generation Process Development of Napabucasin and Impurity Control Strategy
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00001 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 12, 2023 Category: Chemistry Authors: Christopher E. Katz, Bingidimi I. Mobele, Jalal Haddad, Yusuke Yamai, Kazuki Hashimoto, Yujiro Kiyoshima, and Justin Caserta Source Type: research

[ASAP] Some Items of Interest to Process R & D Chemists and Engineers
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00127 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 10, 2023 Category: Chemistry Authors: Alan Steven, Carlos Mateos, Andrei A. Zlota, Christopher C. Nawrat, Alexandre Barthelme, Rik Oost, Paul F. Richardson, Robert B. Kargbo, and John Knight Source Type: research

[ASAP] Scalable Atroposelective Synthesis of MRTX1719: An Inhibitor of the PRMT5/MTA Complex
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00072 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 10, 2023 Category: Chemistry Authors: Michal Achmatowicz, Thomas Scattolin, David R. Snead, Dinesh J. Paymode, Sahar Roshandel, Chen Xie, Guihui Chen, and Cheng-yi Chen Source Type: research

[ASAP] Mass Transport of Diazomethane across Teflon AF2400 Membrane for Scale-Up Development
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00023 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 8, 2023 Category: Chemistry Authors: Filip Horvath-Gerber, King Kuok (Mimi) Hii, Christian Holtze, Eleonore Jeanne Camille Deublein, and Klaus Hellgardt Source Type: research

[ASAP] Continuous Flow Synthesis of Esomeprazole via Asymmetric Sulfoxidation
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00012 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 4, 2023 Category: Chemistry Authors: Tianxiang Gao, Jingnan Zhao, Huinan Sun, Jianing Li, Cunfei Ma, and Qingwei Meng Source Type: research

[ASAP] Route Optimization of the Noncovalent Modulator of Hemoglobin PF-07059013 for Treatment of Sickle Cell Disease through a Palladium-Mediated C –O Coupling, Part II: Pilot Plant Scale Manufacture
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00038 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 4, 2023 Category: Chemistry Authors: Cameron Abercrombie, Christopher P. Ashcroft, Matthew Badland, Aaron Baldwin, Livia T. Baldwin, Sarah Brisley, Wayne Callar, Pedro Daddario, Elaa Hilou, Chintelle James, Ruizhi Li, Yiyang Liu, Sebastien Monfette, Jared L. Piper, Giselle Reyes, Hud Risley, Source Type: research

[ASAP] Assessment of Sulfur Impurities in GMP-Grade Diisopropylcarbodiimide and Their Impact on Coupling Reagent-Induced Side Reactions in Peptide Synthesis
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00099 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 4, 2023 Category: Chemistry Authors: Jan Pawlas and Jon H. Rasmussen Source Type: research

[ASAP] Efficient and Scalable Synthesis of Ketoprofen: A Pyrolytic Aromatization Approach
Organic Process Research& DevelopmentDOI: 10.1021/acs.oprd.3c00049 (Source: Organic Process Research and Development)
Source: Organic Process Research and Development - May 4, 2023 Category: Chemistry Authors: Lili Song, Zhigang Liu, Minjie Liu, Pei Tang, and Fener Chen Source Type: research