Active lupus in Argentina: Results of a multicenter and national registry
CONCLUSION: Active disease was associated with shorter time to diagnosis, worse outcomes (SDI and hospitalizations) and renal, neurological and serosal disease.PMID:37936393 | DOI:10.1177/09612033231209601 (Source: Lupus)
Source: Lupus - November 8, 2023 Category: Rheumatology Authors: Rosana M Quintana Mercedes Garc ía Lucila Garcia Carla Gobbi Paula Alba Ver ónica Bellomio Susana Roverano Analia Patricia Alvarez Cesar Enrique Graf Cecilia Pisoni Alberto Spindler Catalina Gomez Heber Matias Figueredo Silvia Papasidero Raul Paniego Ma Source Type: research
16th International congress on antiphospholipid antibodies task force report on antiphospholipid syndrome laboratory diagnostics and trends
Lupus. 2023 Nov 7:9612033231211820. doi: 10.1177/09612033231211820. Online ahead of print.ABSTRACTClassification criteria for antiphospholipid syndrome (APS) require IgG or IgM isotypes of the anticardiolipin (aCL) antibodies, anti-β2 glycoprotein I (anti-β2GPI) antibodies, and/or the lupus anticoagulant (LA) to satisfy the laboratory disease definition. Over the past 20 years, non-criteria antiphospholipid antibodies (aPL) directed to other proteins of the coagulation cascade (i.e. prothrombin and/or phosphatidylserine-prothrombin complex) or to some domains of β2GPI have been proposed. This task force concentrated and...
Source: Lupus - November 7, 2023 Category: Rheumatology Authors: Tatsuya Atsumi Cecilia B Chighizola Yuichiro Fujieda Ian Mackie Massimo Radin Robert Roubey Maria Laura Bertolaccini Source Type: research
16th International congress on antiphospholipid antibodies task force report on antiphospholipid syndrome laboratory diagnostics and trends
Lupus. 2023 Nov 7:9612033231211820. doi: 10.1177/09612033231211820. Online ahead of print.ABSTRACTClassification criteria for antiphospholipid syndrome (APS) require IgG or IgM isotypes of the anticardiolipin (aCL) antibodies, anti-β2 glycoprotein I (anti-β2GPI) antibodies, and/or the lupus anticoagulant (LA) to satisfy the laboratory disease definition. Over the past 20 years, non-criteria antiphospholipid antibodies (aPL) directed to other proteins of the coagulation cascade (i.e. prothrombin and/or phosphatidylserine-prothrombin complex) or to some domains of β2GPI have been proposed. This task force concentrated and...
Source: Lupus - November 7, 2023 Category: Rheumatology Authors: Tatsuya Atsumi Cecilia B Chighizola Yuichiro Fujieda Ian Mackie Massimo Radin Robert Roubey Maria Laura Bertolaccini Source Type: research
Systemic Lupus Erythematosus and the Ratio of Omega-3 to Omega-6 Fatty Acids Consumption among Women in the Adventist Health Study-2
CONCLUSION: We observed a significant positive association between the ratio of omega-3 to omega-6 fatty acids consumption and prevalence of SLE. Among those with prevalent SLE, their year of starting supplementation of omega-3 and fish oil was closely linked to year of SLE diagnosis. Further, baseline intake of omega-3 fatty acids was not increased among 64 incident SLE cases identified during 6 years of follow-up. Our surprising finding can best be explained by reverse causation. This could be an example of how public health information is assimilated and acted upon by a health conscious public.PMID:37927031 | DOI:10.117...
Source: Lupus - November 6, 2023 Category: Rheumatology Authors: Jisoo Oh Keiji Oda Marissa Brash W Lawrence Beeson Joan Sabat é Gary E Fraser Synnove F Knutsen Source Type: research
COVID-19 and SLE: Infection and autoimmunity at its best
Lupus. 2023 Nov 5:9612033231213914. doi: 10.1177/09612033231213914. Online ahead of print.ABSTRACTIf one had any doubts before the pandemic regarding the correlation between infections and autoimmunity, COVID-19 left us fascinated on the strong bond between the two entities. The immune and autoimmune reactions seen in patients infected with SARS-CoV-2 have served as a base for this assumption. Later on, the use of immunosuppressants such as systemic glucocorticoids, among other biological agents, turned this assumption to a fact. This was no different when it comes to the vaccines against COVID-19. Through several postulat...
Source: Lupus - November 6, 2023 Category: Rheumatology Authors: Naim Mahroum Abdulrahman Elsalti Mehmet Fatih Ozkan Yehuda Shoenfeld Source Type: research
Efficacy of the COVID-19 vaccine in pediatric systemic lupus erythematosus patients
Lupus. 2023 Nov 6:9612033231208336. doi: 10.1177/09612033231208336. Online ahead of print.NO ABSTRACTPMID:37931076 | DOI:10.1177/09612033231208336 (Source: Lupus)
Source: Lupus - November 6, 2023 Category: Rheumatology Authors: Yi Shi Sangeeta Sule Catherine Park Sun-Young Ahn Source Type: research
Systemic Lupus Erythematosus and the Ratio of Omega-3 to Omega-6 Fatty Acids Consumption among Women in the Adventist Health Study-2
CONCLUSION: We observed a significant positive association between the ratio of omega-3 to omega-6 fatty acids consumption and prevalence of SLE. Among those with prevalent SLE, their year of starting supplementation of omega-3 and fish oil was closely linked to year of SLE diagnosis. Further, baseline intake of omega-3 fatty acids was not increased among 64 incident SLE cases identified during 6 years of follow-up. Our surprising finding can best be explained by reverse causation. This could be an example of how public health information is assimilated and acted upon by a health conscious public.PMID:37927031 | DOI:10.117...
Source: Lupus - November 6, 2023 Category: Rheumatology Authors: Jisoo Oh Keiji Oda Marissa Brash W Lawrence Beeson Joan Sabat é Gary E Fraser Synnove F Knutsen Source Type: research
COVID-19 and SLE: Infection and autoimmunity at its best
Lupus. 2023 Nov 5:9612033231213914. doi: 10.1177/09612033231213914. Online ahead of print.ABSTRACTIf one had any doubts before the pandemic regarding the correlation between infections and autoimmunity, COVID-19 left us fascinated on the strong bond between the two entities. The immune and autoimmune reactions seen in patients infected with SARS-CoV-2 have served as a base for this assumption. Later on, the use of immunosuppressants such as systemic glucocorticoids, among other biological agents, turned this assumption to a fact. This was no different when it comes to the vaccines against COVID-19. Through several postulat...
Source: Lupus - November 6, 2023 Category: Rheumatology Authors: Naim Mahroum Abdulrahman Elsalti Mehmet Fatih Ozkan Yehuda Shoenfeld Source Type: research
Impact of telemedicine on disease activity assessment: A case-crossover study nested within a cohort of patients with systemic lupus erythematosus
CONCLUSION: We found that telemedicine assessment was associated with a much higher disease activity score than subsequent assessments, which may suggest an overestimation of disease activity and later assessment accuracy. Cautious adoption has been suggested for SLE patients with active disease.PMID:37921574 | DOI:10.1177/09612033231211855 (Source: Lupus)
Source: Lupus - November 3, 2023 Category: Rheumatology Authors: Ibrahim Almaghlouth Haya M Almalag Hajer Alzuhair Rafif Alsaigh Asma Bedaiwi Lena M Hassen Sulaiman Alzomia Boshra Alanazi Abdulaziz Mohammed Alabdulkareem Saud Alahmari Kazi Nur Asfina Najma Khalil Mohammed A Omair Mohamed Bedaiwi Source Type: research
Impact of telemedicine on disease activity assessment: A case-crossover study nested within a cohort of patients with systemic lupus erythematosus
CONCLUSION: We found that telemedicine assessment was associated with a much higher disease activity score than subsequent assessments, which may suggest an overestimation of disease activity and later assessment accuracy. Cautious adoption has been suggested for SLE patients with active disease.PMID:37921574 | DOI:10.1177/09612033231211855 (Source: Lupus)
Source: Lupus - November 3, 2023 Category: Rheumatology Authors: Ibrahim Almaghlouth Haya M Almalag Hajer Alzuhair Rafif Alsaigh Asma Bedaiwi Lena M Hassen Sulaiman Alzomia Boshra Alanazi Abdulaziz Mohammed Alabdulkareem Saud Alahmari Kazi Nur Asfina Najma Khalil Mohammed A Omair Mohamed Bedaiwi Source Type: research
Impact of telemedicine on disease activity assessment: A case-crossover study nested within a cohort of patients with systemic lupus erythematosus
CONCLUSION: We found that telemedicine assessment was associated with a much higher disease activity score than subsequent assessments, which may suggest an overestimation of disease activity and later assessment accuracy. Cautious adoption has been suggested for SLE patients with active disease.PMID:37921574 | DOI:10.1177/09612033231211855 (Source: Lupus)
Source: Lupus - November 3, 2023 Category: Rheumatology Authors: Ibrahim Almaghlouth Haya M Almalag Hajer Alzuhair Rafif Alsaigh Asma Bedaiwi Lena M Hassen Sulaiman Alzomia Boshra Alanazi Abdulaziz Mohammed Alabdulkareem Saud Alahmari Kazi Nur Asfina Najma Khalil Mohammed A Omair Mohamed Bedaiwi Source Type: research
Thrombosis and APS: Lessons Learned from Another Black Swan Tale
Lupus. 2023 Nov 2:9612033231212088. doi: 10.1177/09612033231212088. Online ahead of print.ABSTRACTAntiphospholipid syndrome (APS) is a chronic systemic autoimmune disease characterized by venous, arterial, and microvascular thromboses and/or recurrent pregnancy morbidity, that occur in the persistent presence of antiphospholipid antibodies (aPL). APS can present with a wide range of clinical manifestations often reffered as "extra-criteria". These features, although apparently less common, can severely impact patients' outcome. Here, we report the case of a patient with a newly diagnosed APS. He previously experienced a re...
Source: Lupus - November 2, 2023 Category: Rheumatology Authors: Sofia Camerlo Irene Cecchi Silvia Grazietta Foddai Massimo Radin Alice Barinotti Alessandro Morotti Dario Roccatello Savino Sciascia Source Type: research
Renal tubular and glomerular estrogen receptor ß levels are lower in lupus nephritis than in familial Mediterranean fever-associated renal amyloidosis
CONCLUSIONS: This study showed that tubular estrogen receptor ß expression score was elevated in familial Mediterranean fever amyloidosis and correlated with serum creatinine levels and renal crescents.PMID:37908062 | DOI:10.1177/09612033231210728 (Source: Lupus)
Source: Lupus - November 1, 2023 Category: Rheumatology Authors: Ahmet Kor Nuran S üngü Cemile Bi çer Şükran Erten Source Type: research
Subclinical macular vessel density alterations in patients with juvenile systemic lupus erythematosus
CONCLUSIONS: We demonstrated decreased VD in all layers of the retina and CC in patients with JSLE without ocular involvement. Early screening and close follow-up were recommended.PMID:37909478 | DOI:10.1177/09612033231212524 (Source: Lupus)
Source: Lupus - November 1, 2023 Category: Rheumatology Authors: Sisi Xu Yu Zhang Source Type: research
Renal tubular and glomerular estrogen receptor ß levels are lower in lupus nephritis than in familial Mediterranean fever-associated renal amyloidosis
CONCLUSIONS: This study showed that tubular estrogen receptor ß expression score was elevated in familial Mediterranean fever amyloidosis and correlated with serum creatinine levels and renal crescents.PMID:37908062 | DOI:10.1177/09612033231210728 (Source: Lupus)
Source: Lupus - November 1, 2023 Category: Rheumatology Authors: Ahmet Kor Nuran S üngü Cemile Bi çer Şükran Erten Source Type: research
