Journal of the Mechanical Behavior of Biomedical Materials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Differences in the mechanical properties of intestinal tissue based on preservation freezing duration and temperature
In this study, tissue samples were stress tested to determine if freezing duration and temperature alter their mechanical properties. Tissue samples taken from the small intestine of pigs were assigned to 5 groups: fresh tissue, -28.9 °C for 7 days, -62.2 °C for 7 days, -28.9 °C for 30 days, and -62.2 °C for 30 days. Tissue was stored in PBS for the assigned temperature and duration until testing occurred with the exception of fresh tissue which was tested at sample collection. Before testing, samples were thawed in a room temperature bath, and the thickness was measured. Samples were then mounted in a biaxial test sys...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 10, 2024 Category: Materials Science Authors: Gregory S Hirst Sunandita Sarker Benjamin S Terry Source Type: research

Reinforcement hybridization in staggered composites enhances wave attenuation performance
In this study, we develop the hybrid dynamic shear-lag model with Bloch's theorem to investigate the hybrid effect of reinforcement on wave attenuation in bioinspired staggered composites. We present for the first time the relationship between macroscopic wave filtering and hybridization of building blocks in staggered composites. Viscoelasticity was taken into account for both reinforcement and matrix to reflect the damping effect on wave transmission. Our findings indicate that reinforcement hybridization significantly enhances wave attenuation performance through two critical parameters: the linear stiffness and linear ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 10, 2024 Category: Materials Science Authors: Junjie Liu Hangyuan Zhang Yang Gao Zhongliang Yu Chaonan Cong Xiaoding Wei Qingsheng Yang Source Type: research

Skin viscoelasticity effects on the periodic mechanical stimuli propagation between skin layers
J Mech Behav Biomed Mater. 2024 Feb 3;152:106416. doi: 10.1016/j.jmbbm.2024.106416. Online ahead of print.ABSTRACTOur daily lives are constantly surrounded by dynamic stimuli, and our skin is deformed in a time-dependent manner. Although skin plays an important role in transmitting stimuli received at the surface to mechanoreceptors, few studies have investigated how differences in skin viscoelasticity affect the mechanical stimuli propagation in the skin. Therefore, using a finite element model, we evaluated the effects and trends of changes in the stiffness and viscoelasticity of the skin on the propagation of mechanical...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 9, 2024 Category: Materials Science Authors: Saito Sakaguchi Masashi Konyo Source Type: research

Hierarchical porous PLLA/ACP fibrous membrane towards bone tissue scaffold
This study focuses on the incorporation of amorphous calcium phosphate (ACP) nanoparticles into poly(L-lactic acid) (PLLA) to produce electrospun PLLA/ACP fibrous membranes. Subsequent treatment with acetone yielded a hierarchical porous structure, boasting an ultra-high surface area of 94.7753 ± 0.3884 m2/g. The ACP nanoparticles, initially encapsulated by PLLA, were exposed on the fibre surface after acetone treatment. Furthermore, the porous PLLA/ACP fibrous membrane exhibited superior mechanical properties (Young's modulus = 0.148 GPa, tensile strength = 3.05 MPa) and enhanced wettability. In a 7-day in vitro cell cul...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 9, 2024 Category: Materials Science Authors: Chen Meng Xuzhao Liu Jiashen Li Source Type: research

Leaflet remodeling reduces tricuspid valve function in a computational model
J Mech Behav Biomed Mater. 2024 Feb 2;152:106453. doi: 10.1016/j.jmbbm.2024.106453. Online ahead of print.ABSTRACTTricuspid valve leaflets have historically been considered "passive flaps". However, we have recently shown that tricuspid leaflets actively remodel in sheep with functional tricuspid regurgitation. We hypothesize that these remodeling-induced changes reduce leaflet coaptation and, therefore, contribute to valvular dysfunction. To test this, we simulated the impact of remodeling-induced changes on valve mechanics in a reverse-engineered computer model of the human tricuspid valve. To this end, we combined right...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 9, 2024 Category: Materials Science Authors: Mrudang Mathur Marcin Malinowski Tomasz Jazwiec Tomasz A Timek Manuel K Rausch Source Type: research

Developing a transcatheter injectable nanoclay- alginate gel for minimally invasive procedures
In this study, a laponite nanoclay (NC)/alginate gel embolic agent was developed, characterized, and studied for transcatheter based minimally invasive procedures. Both NC and alginate are biocompatible and FDA-approved. Due to electrostatic interactions, the NC/alginate gels exhibit shear-thinning properties that are desirable for transcatheter delivery. The unique shear-thinning nature of the NC/alginate gel allows it to function as a fluid-like substance during transcatheter delivery and as a solid-like embolic agent once deployed. To ensure optimal performance and safety in clinical applications, the rheological charac...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 9, 2024 Category: Materials Science Authors: Keren Zhao George Varghese P J Peng Chen Jingjie Hu Source Type: research

Compressive mechanical properties of dry antler cortical bone cylinders from different cervidae species
This study highlights the fact that compression of antler cortical bone cylinders following current guidelines is feasible but not applicable in all species. Standardization of the testing protocols could help to compare data from the literature. This study also confirms that sample localization has no effect on the mechanical properties, that sample density has a significant impact and allows enriching the knowledge of the mechanical properties of dry antler cortical bone.PMID:38330876 | DOI:10.1016/j.jmbbm.2024.106442 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 8, 2024 Category: Materials Science Authors: Pierre P Picavet St éphanie Claeys Etienne Rondia Marc Balligand Source Type: research

In vitro drug release and cartilage interface lubrication properties of biomimetic polymers
J Mech Behav Biomed Mater. 2024 Jan 29;152:106439. doi: 10.1016/j.jmbbm.2024.106439. Online ahead of print.ABSTRACTOsteoarthritis is a degenerative disease that is widely found in the elderly population, with a trend towards a younger age group in recent years. In the early stages of arthritis, patients are treated with hyaluronic acid injections and anti-inflammatory drugs. However, it has been found that hyaluronic acid can only play a supportive role and does not have a lubricating effect, and due to the absence of blood vessels, nerves, and lymphatic vessels in the articular cartilage, the oral anti-inflammatory drugs ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 7, 2024 Category: Materials Science Authors: Chenyang Gong Lingling Cui Dangsheng Xiong Yan Ding Source Type: research

Polymerization shrinkage of contemporary dental resin composites: Comparison of three measurement methods with correlation analysis
J Mech Behav Biomed Mater. 2024 Feb 1;152:106450. doi: 10.1016/j.jmbbm.2024.106450. Online ahead of print.ABSTRACTThe aim of this study was to evaluate a novel approach for measuring the polymerization shrinkage of dental resin composites - measurement of sample depth variation. This new method was compared with two testing methodologies used for assessing the polymerization shrinkage (buoyancy and strain gauge methods). Eleven commercial resin composites were investigated (EverX Posterior; EverX Flow Bulk & Dentin; G-aenial Anterior, Posterior, A'chord & Universal Injectable; Filtek One Bulk Fill & Universal R...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 7, 2024 Category: Materials Science Authors: Agata Szczesio-Wlodarczyk Sufyan Garoushi Pekka Vallittu Kinga Bociong Lippo Lassila Source Type: research

Decoration with electronegative 2D materials based on chemical transition layers on CFR-PEEK implants for promoting osteogenesis
J Mech Behav Biomed Mater. 2024 Feb 3;152:106436. doi: 10.1016/j.jmbbm.2024.106436. Online ahead of print.ABSTRACTDue to the unique lamellar structures, physicochemical and biological properties, electronegative two-dimensional (2D) materials have been explored for surface modification of carbon fibers reinforced polyetheretherketone (CFR-PEEK) composite. Deposition of electronegative 2D materials based on a porous surface created by concentrated H2SO4 has been studied to promote osteogenesis of CFR-PEEK. Generally, a porous layer will be pre-built on CFR-PEEK through severe corrosion of concentrated sulfuric acid to help ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 7, 2024 Category: Materials Science Authors: Wen Qin Tong Xing Jing Ma Bin Tang Weiyi Chen Source Type: research

An integrated mechanical degradation model to explore the mechanical response of a bioresorbable polymeric scaffold
This study presents an integrated degradation framework which couples a physically-based degradation model, which predicts changes in both crystallinity (Xc) and molecular weight (Mn), with the results of a micromechanical model, which predicts the effective properties of the semicrystalline polymer. This degradation framework is used to simulate the deployment of a bioresorbable PLLA (Poly (L-lactide) stent into a mock vessel and the subsequent mechanical response during degradation under different diffusion boundary conditions representing neointimal growth. A workflow is established in a commercial finite element code t...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 7, 2024 Category: Materials Science Authors: A R Abaei Connor J Shine T J Vaughan W Ronan Source Type: research

Fabrication and biomechanical characterization of a spider silk reinforced fibrin-based vascular prosthesis
J Mech Behav Biomed Mater. 2024 Feb 1;152:106433. doi: 10.1016/j.jmbbm.2024.106433. Online ahead of print.ABSTRACTWith fibrin-based vascular prostheses, vascular tissue engineering offers a promising approach for the fabrication of biologically active regenerative vascular grafts. As a potentially autologous biomaterial, fibrin exhibits excellent hemo- and biocompatibility. However, the major problem in the use of fibrin constructs in vascular tissue engineering, which has so far prevented their widespread clinical application, is the insufficient biomechanical stability of unprocessed fibrin matrices. In this proof-of-con...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 5, 2024 Category: Materials Science Authors: Clara Glomb Mathias Wilhelmi Sarah Strau ß Sarah Zippusch Melanie Klingenberg Thomas Aper Peter M Vogt Arjang Ruhparwar Florian Helms Source Type: research

A novel mussel-inspired desensitizer based on radial mesoporous bioactive nanoglass for the treatment of dentin exposure: An in vitro study
CONCLUSION: The application of RMBG@PDA with superior dentin tubule occlusion ability and acid/abrasion-resistant stability can provide a therapeutic strategy for the prevention and the management of dentin hypersensitivity.PMID:38310812 | DOI:10.1016/j.jmbbm.2024.106420 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 4, 2024 Category: Materials Science Authors: Tianjia Huang Jieyong Jia Changze Zhu Jing Tian Shiyi Zhang Xiaoxi Yang Bo Lei Yuncong Li Source Type: research

Calcium silicate/gelatin composite scaffolds with controllable degradation behavior: Fabrication and evaluation
J Mech Behav Biomed Mater. 2024 Feb 1;152:106422. doi: 10.1016/j.jmbbm.2024.106422. Online ahead of print.ABSTRACTCalcium silicate can be used as an excellent material for biodegradable bone scaffolds because it can provide bioactive ions to promote bone regeneration. However, the brittleness and rapid degradation of calcium silicate scaffolds have significantly limited their clinical application. In this work, the calcium silicate scaffolds printed by DLP technology were immersed in a gelatin solution under high vacuum condition to obtain calcium silicate/gelatin composite scaffolds with good mechanical and biological pro...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 4, 2024 Category: Materials Science Authors: Yanlong Wu Xu Chen Jianfeng Kang Yongqiang Yang Xin Zhao Yaxiong Liu Jian Qiao Source Type: research

Thermoplastic clear dental aligners under cyclic compression loading: A mechanical performance analysis using acoustic emission technique
The objective of this work is to analyse the performance of clear aligners made of thermoplastic materials. Within this framework, the damage evolution stages and damage states of the aligners at different cycles of the compressive loading are evaluated using the Acoustic Emission (AE) technique. Three different clear aligner systems were prepared: thermoformed PET-g (polyethylene terephthalate glycol) and PU (polyurethane), and additively manufactured PU. Cyclic compression tests are performed to simulate 22500 swallows. The mechanical results show that the energy absorbed by the thermoformed PET-g aligner remains stable ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 4, 2024 Category: Materials Science Authors: Claudia Barile Claudia Cianci Vimalathithan Paramsamy Kannan Giovanni Pappalettera Carmine Pappalettere Caterina Casavola Carmela Suriano Domenico Ciavarella Source Type: research