Journal of the Mechanical Behavior of Biomedical Materials This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Leaflet remodeling reduces tricuspid valve function in a computational model
J Mech Behav Biomed Mater. 2024 Feb 2;152:106453. doi: 10.1016/j.jmbbm.2024.106453. Online ahead of print.ABSTRACTTricuspid valve leaflets have historically been considered "passive flaps". However, we have recently shown that tricuspid leaflets actively remodel in sheep with functional tricuspid regurgitation. We hypothesize that these remodeling-induced changes reduce leaflet coaptation and, therefore, contribute to valvular dysfunction. To test this, we simulated the impact of remodeling-induced changes on valve mechanics in a reverse-engineered computer model of the human tricuspid valve. To this end, we combined right...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 9, 2024 Category: Materials Science Authors: Mrudang Mathur Marcin Malinowski Tomasz Jazwiec Tomasz A Timek Manuel K Rausch Source Type: research

Developing a transcatheter injectable nanoclay- alginate gel for minimally invasive procedures
In this study, a laponite nanoclay (NC)/alginate gel embolic agent was developed, characterized, and studied for transcatheter based minimally invasive procedures. Both NC and alginate are biocompatible and FDA-approved. Due to electrostatic interactions, the NC/alginate gels exhibit shear-thinning properties that are desirable for transcatheter delivery. The unique shear-thinning nature of the NC/alginate gel allows it to function as a fluid-like substance during transcatheter delivery and as a solid-like embolic agent once deployed. To ensure optimal performance and safety in clinical applications, the rheological charac...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 9, 2024 Category: Materials Science Authors: Keren Zhao George Varghese P J Peng Chen Jingjie Hu Source Type: research

Compressive mechanical properties of dry antler cortical bone cylinders from different cervidae species
This study highlights the fact that compression of antler cortical bone cylinders following current guidelines is feasible but not applicable in all species. Standardization of the testing protocols could help to compare data from the literature. This study also confirms that sample localization has no effect on the mechanical properties, that sample density has a significant impact and allows enriching the knowledge of the mechanical properties of dry antler cortical bone.PMID:38330876 | DOI:10.1016/j.jmbbm.2024.106442 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 8, 2024 Category: Materials Science Authors: Pierre P Picavet St éphanie Claeys Etienne Rondia Marc Balligand Source Type: research

In vitro drug release and cartilage interface lubrication properties of biomimetic polymers
J Mech Behav Biomed Mater. 2024 Jan 29;152:106439. doi: 10.1016/j.jmbbm.2024.106439. Online ahead of print.ABSTRACTOsteoarthritis is a degenerative disease that is widely found in the elderly population, with a trend towards a younger age group in recent years. In the early stages of arthritis, patients are treated with hyaluronic acid injections and anti-inflammatory drugs. However, it has been found that hyaluronic acid can only play a supportive role and does not have a lubricating effect, and due to the absence of blood vessels, nerves, and lymphatic vessels in the articular cartilage, the oral anti-inflammatory drugs ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 7, 2024 Category: Materials Science Authors: Chenyang Gong Lingling Cui Dangsheng Xiong Yan Ding Source Type: research

Polymerization shrinkage of contemporary dental resin composites: Comparison of three measurement methods with correlation analysis
J Mech Behav Biomed Mater. 2024 Feb 1;152:106450. doi: 10.1016/j.jmbbm.2024.106450. Online ahead of print.ABSTRACTThe aim of this study was to evaluate a novel approach for measuring the polymerization shrinkage of dental resin composites - measurement of sample depth variation. This new method was compared with two testing methodologies used for assessing the polymerization shrinkage (buoyancy and strain gauge methods). Eleven commercial resin composites were investigated (EverX Posterior; EverX Flow Bulk & Dentin; G-aenial Anterior, Posterior, A'chord & Universal Injectable; Filtek One Bulk Fill & Universal R...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 7, 2024 Category: Materials Science Authors: Agata Szczesio-Wlodarczyk Sufyan Garoushi Pekka Vallittu Kinga Bociong Lippo Lassila Source Type: research

Decoration with electronegative 2D materials based on chemical transition layers on CFR-PEEK implants for promoting osteogenesis
J Mech Behav Biomed Mater. 2024 Feb 3;152:106436. doi: 10.1016/j.jmbbm.2024.106436. Online ahead of print.ABSTRACTDue to the unique lamellar structures, physicochemical and biological properties, electronegative two-dimensional (2D) materials have been explored for surface modification of carbon fibers reinforced polyetheretherketone (CFR-PEEK) composite. Deposition of electronegative 2D materials based on a porous surface created by concentrated H2SO4 has been studied to promote osteogenesis of CFR-PEEK. Generally, a porous layer will be pre-built on CFR-PEEK through severe corrosion of concentrated sulfuric acid to help ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 7, 2024 Category: Materials Science Authors: Wen Qin Tong Xing Jing Ma Bin Tang Weiyi Chen Source Type: research

An integrated mechanical degradation model to explore the mechanical response of a bioresorbable polymeric scaffold
This study presents an integrated degradation framework which couples a physically-based degradation model, which predicts changes in both crystallinity (Xc) and molecular weight (Mn), with the results of a micromechanical model, which predicts the effective properties of the semicrystalline polymer. This degradation framework is used to simulate the deployment of a bioresorbable PLLA (Poly (L-lactide) stent into a mock vessel and the subsequent mechanical response during degradation under different diffusion boundary conditions representing neointimal growth. A workflow is established in a commercial finite element code t...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 7, 2024 Category: Materials Science Authors: A R Abaei Connor J Shine T J Vaughan W Ronan Source Type: research

Fabrication and biomechanical characterization of a spider silk reinforced fibrin-based vascular prosthesis
J Mech Behav Biomed Mater. 2024 Feb 1;152:106433. doi: 10.1016/j.jmbbm.2024.106433. Online ahead of print.ABSTRACTWith fibrin-based vascular prostheses, vascular tissue engineering offers a promising approach for the fabrication of biologically active regenerative vascular grafts. As a potentially autologous biomaterial, fibrin exhibits excellent hemo- and biocompatibility. However, the major problem in the use of fibrin constructs in vascular tissue engineering, which has so far prevented their widespread clinical application, is the insufficient biomechanical stability of unprocessed fibrin matrices. In this proof-of-con...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 5, 2024 Category: Materials Science Authors: Clara Glomb Mathias Wilhelmi Sarah Strau ß Sarah Zippusch Melanie Klingenberg Thomas Aper Peter M Vogt Arjang Ruhparwar Florian Helms Source Type: research

A novel mussel-inspired desensitizer based on radial mesoporous bioactive nanoglass for the treatment of dentin exposure: An in vitro study
CONCLUSION: The application of RMBG@PDA with superior dentin tubule occlusion ability and acid/abrasion-resistant stability can provide a therapeutic strategy for the prevention and the management of dentin hypersensitivity.PMID:38310812 | DOI:10.1016/j.jmbbm.2024.106420 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 4, 2024 Category: Materials Science Authors: Tianjia Huang Jieyong Jia Changze Zhu Jing Tian Shiyi Zhang Xiaoxi Yang Bo Lei Yuncong Li Source Type: research

Calcium silicate/gelatin composite scaffolds with controllable degradation behavior: Fabrication and evaluation
J Mech Behav Biomed Mater. 2024 Feb 1;152:106422. doi: 10.1016/j.jmbbm.2024.106422. Online ahead of print.ABSTRACTCalcium silicate can be used as an excellent material for biodegradable bone scaffolds because it can provide bioactive ions to promote bone regeneration. However, the brittleness and rapid degradation of calcium silicate scaffolds have significantly limited their clinical application. In this work, the calcium silicate scaffolds printed by DLP technology were immersed in a gelatin solution under high vacuum condition to obtain calcium silicate/gelatin composite scaffolds with good mechanical and biological pro...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 4, 2024 Category: Materials Science Authors: Yanlong Wu Xu Chen Jianfeng Kang Yongqiang Yang Xin Zhao Yaxiong Liu Jian Qiao Source Type: research

Thermoplastic clear dental aligners under cyclic compression loading: A mechanical performance analysis using acoustic emission technique
The objective of this work is to analyse the performance of clear aligners made of thermoplastic materials. Within this framework, the damage evolution stages and damage states of the aligners at different cycles of the compressive loading are evaluated using the Acoustic Emission (AE) technique. Three different clear aligner systems were prepared: thermoformed PET-g (polyethylene terephthalate glycol) and PU (polyurethane), and additively manufactured PU. Cyclic compression tests are performed to simulate 22500 swallows. The mechanical results show that the energy absorbed by the thermoformed PET-g aligner remains stable ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 4, 2024 Category: Materials Science Authors: Claudia Barile Claudia Cianci Vimalathithan Paramsamy Kannan Giovanni Pappalettera Carmine Pappalettere Caterina Casavola Carmela Suriano Domenico Ciavarella Source Type: research

Gaussian random field-based characterization and reconstruction of cancellous bone microstructure considering the constraint of correlation structure
J Mech Behav Biomed Mater. 2024 Jan 29;152:106443. doi: 10.1016/j.jmbbm.2024.106443. Online ahead of print.ABSTRACTThe macro scale physical properties of cancellous bone materials are governed by the microstructural features, which is of great significance for the multi-scale research of cancellous bone and the inverse design of bone-mimicking materials. Therefore, it is essential to characterize the natural cancellous bone samples, and reconstruct the microstructures with the biomimetic osteointegration and mechanical properties. In this research, a novel approach for the characterization and reconstruction of cancellous ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 3, 2024 Category: Materials Science Authors: Lei He Moxin Zhao Jason Pui Yin Cheung Teng Zhang Xiaodan Ren Source Type: research

Structural descriptor and surrogate modeling for design of biodegradable scaffolds
J Mech Behav Biomed Mater. 2024 Jan 22;152:106415. doi: 10.1016/j.jmbbm.2024.106415. Online ahead of print.ABSTRACTBiodegradable scaffolds are important to regenerative medicine in that they provide an amicable environment for tissue regrowth. However, establishing structure-property (SP) relationships for scaffold design is challenging due to the complexity of the three-dimensional porous scaffold geometry. The complexity requires high-dimensional geometric descriptors. The training of such a SP surrogate model will need a large amount of experimental or simulation data. In this work, a schema of constructing SP relations...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 1, 2024 Category: Materials Science Authors: Jesse M Sestito Tequila A L Harris Yan Wang Source Type: research

Accuracy of additively manufactured and steam sterilized surgical guides by means of continuous liquid interface production, stereolithography, digital light processing, and fused filament fabrication
In conclusion, the different printing technologies and orientations had little effect on the manufacturing accuracy of the surgical guides before sterilization. However, after sterilization, FFF surgical guides exhibited significant deformation making their clinical use impossible. CLIP showed larger deformations due to steam sterilization than the other photopolymerizing techniques, however, discrepancies may be considered within the range of clinical acceptance. The influence on the implant position remains to be evaluated.PMID:38295512 | DOI:10.1016/j.jmbbm.2024.106418 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 31, 2024 Category: Materials Science Authors: Felix Burkhardt Leon Handermann Severin Rothlauf Aiste Gintaute Kirstin Vach Benedikt C Spies J örg Lüchtenborg Source Type: research

Tailoring mechanical properties in 3D printed multimaterial architected structures
This study explores the unique opportunity offered by multimaterial 3D printing in fine-tuning the mechanical performance of architected structures. The exploration of the programmability of these structures involves a systematic assessment of various material candidates. After careful evaluation, the selection process led to the choice of PLA and PCL biopolymers for the multimaterial structure. Experimental results emphasize the key role of design configurations in influencing mechanical characteristics, particularly in enhancing the energy absorption capacity of architected structures. By skillfully manipulating the loca...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 30, 2024 Category: Materials Science Authors: Mehrshad Mehrpouya Ava Ghalayaniesfahani Jonne F Postmes Ian Gibson Source Type: research