Calcium silicate/gelatin composite scaffolds with controllable degradation behavior: Fabrication and evaluation
J Mech Behav Biomed Mater. 2024 Feb 1;152:106422. doi: 10.1016/j.jmbbm.2024.106422. Online ahead of print.ABSTRACTCalcium silicate can be used as an excellent material for biodegradable bone scaffolds because it can provide bioactive ions to promote bone regeneration. However, the brittleness and rapid degradation of calcium silicate scaffolds have significantly limited their clinical application. In this work, the calcium silicate scaffolds printed by DLP technology were immersed in a gelatin solution under high vacuum condition to obtain calcium silicate/gelatin composite scaffolds with good mechanical and biological pro...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 4, 2024 Category: Materials Science Authors: Yanlong Wu Xu Chen Jianfeng Kang Yongqiang Yang Xin Zhao Yaxiong Liu Jian Qiao Source Type: research

Thermoplastic clear dental aligners under cyclic compression loading: A mechanical performance analysis using acoustic emission technique
The objective of this work is to analyse the performance of clear aligners made of thermoplastic materials. Within this framework, the damage evolution stages and damage states of the aligners at different cycles of the compressive loading are evaluated using the Acoustic Emission (AE) technique. Three different clear aligner systems were prepared: thermoformed PET-g (polyethylene terephthalate glycol) and PU (polyurethane), and additively manufactured PU. Cyclic compression tests are performed to simulate 22500 swallows. The mechanical results show that the energy absorbed by the thermoformed PET-g aligner remains stable ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 4, 2024 Category: Materials Science Authors: Claudia Barile Claudia Cianci Vimalathithan Paramsamy Kannan Giovanni Pappalettera Carmine Pappalettere Caterina Casavola Carmela Suriano Domenico Ciavarella Source Type: research

Gaussian random field-based characterization and reconstruction of cancellous bone microstructure considering the constraint of correlation structure
J Mech Behav Biomed Mater. 2024 Jan 29;152:106443. doi: 10.1016/j.jmbbm.2024.106443. Online ahead of print.ABSTRACTThe macro scale physical properties of cancellous bone materials are governed by the microstructural features, which is of great significance for the multi-scale research of cancellous bone and the inverse design of bone-mimicking materials. Therefore, it is essential to characterize the natural cancellous bone samples, and reconstruct the microstructures with the biomimetic osteointegration and mechanical properties. In this research, a novel approach for the characterization and reconstruction of cancellous ...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 3, 2024 Category: Materials Science Authors: Lei He Moxin Zhao Jason Pui Yin Cheung Teng Zhang Xiaodan Ren Source Type: research

Structural descriptor and surrogate modeling for design of biodegradable scaffolds
J Mech Behav Biomed Mater. 2024 Jan 22;152:106415. doi: 10.1016/j.jmbbm.2024.106415. Online ahead of print.ABSTRACTBiodegradable scaffolds are important to regenerative medicine in that they provide an amicable environment for tissue regrowth. However, establishing structure-property (SP) relationships for scaffold design is challenging due to the complexity of the three-dimensional porous scaffold geometry. The complexity requires high-dimensional geometric descriptors. The training of such a SP surrogate model will need a large amount of experimental or simulation data. In this work, a schema of constructing SP relations...
Source: Journal of the Mechanical Behavior of Biomedical Materials - February 1, 2024 Category: Materials Science Authors: Jesse M Sestito Tequila A L Harris Yan Wang Source Type: research

Accuracy of additively manufactured and steam sterilized surgical guides by means of continuous liquid interface production, stereolithography, digital light processing, and fused filament fabrication
In conclusion, the different printing technologies and orientations had little effect on the manufacturing accuracy of the surgical guides before sterilization. However, after sterilization, FFF surgical guides exhibited significant deformation making their clinical use impossible. CLIP showed larger deformations due to steam sterilization than the other photopolymerizing techniques, however, discrepancies may be considered within the range of clinical acceptance. The influence on the implant position remains to be evaluated.PMID:38295512 | DOI:10.1016/j.jmbbm.2024.106418 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 31, 2024 Category: Materials Science Authors: Felix Burkhardt Leon Handermann Severin Rothlauf Aiste Gintaute Kirstin Vach Benedikt C Spies J örg Lüchtenborg Source Type: research

Tailoring mechanical properties in 3D printed multimaterial architected structures
This study explores the unique opportunity offered by multimaterial 3D printing in fine-tuning the mechanical performance of architected structures. The exploration of the programmability of these structures involves a systematic assessment of various material candidates. After careful evaluation, the selection process led to the choice of PLA and PCL biopolymers for the multimaterial structure. Experimental results emphasize the key role of design configurations in influencing mechanical characteristics, particularly in enhancing the energy absorption capacity of architected structures. By skillfully manipulating the loca...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 30, 2024 Category: Materials Science Authors: Mehrshad Mehrpouya Ava Ghalayaniesfahani Jonne F Postmes Ian Gibson Source Type: research

Scope of magnesium ceria nanocomposites for mandibular reconstruction: Degradation and biomechanical evaluation using a 3-dimensional finite element analysis approach
J Mech Behav Biomed Mater. 2024 Jan 24;152:106424. doi: 10.1016/j.jmbbm.2024.106424. Online ahead of print.ABSTRACTMagnesium/Ceria nanocomposites (Mg/xCeO2 NCs (x = 0.5 %, 1 % and 1.5 %)) prepared by using powder metallurgy and microwave sintering method are assessed for their corrosion rate for a period of 28 days. As per the immersion tests results, the addition of ceria nanoparticles to pure Mg, brought about a noteworthy improvement to corrosion resistance. A corrosion rate of approximately 0.84 mm/year for Mg/0.5CeO2 and 0.99 mm/year for Mg/1.0CeO2 nanocomposites were observed. Another aspect of the study involves emp...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 30, 2024 Category: Materials Science Authors: Milli Suchita Kujur Anirudh Venkatraman Krishnan Vyasaraj Manakari Gururaj Parande Hajo Dieringa Ashis Mallick Manoj Gupta Source Type: research

Optimization by mixture design of chitosan/multi-phase calcium phosphate/BMP-2 biomimetic scaffolds for bone tissue engineering
This study aimed to improve the physicochemical properties of chitosan/multi-phase calcium phosphate (MCaP) scaffolds using an optimized mixture design experiment and evaluate the effect of biofunctionalization of the obtained scaffolds with the bone morphogenetic protein BMP-2 on stem cell behavior. The present study evaluated the compressive strength, elastic modulus, porosity, pore diameter, and degradation in simulated body fluids and integrated these responses using desirability. The properties of the scaffolds with the best desirability (18.4% of MCaP) were: compressive strength of 23 kPa, elastic modulus of 430 kPa,...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 30, 2024 Category: Materials Science Authors: Mateo Escobar Jaramillo Cristian Covarrubias Edwin Pati ño González Claudia Patricia Ossa Orozco Source Type: research

High-resolution local trabecular strain within trabecular structure under cyclic loading
This study employed DIC equipped with a telecentric lens to investigate the strain state of individual trabeculae within their trabecular structure by assessing the longitudinal strain of the trabeculae at both the middle and near the edges of the trabeculae. Due to the high-resolution of the used DIC system, local surface strain of trabeculae was analyzed too. Lastly, the correlation between longitudinal trabecular strain and the orientation and slenderness of the trabeculae was investigated. The results showed that the strain magnification close to the edge of the trabeculae was higher and reached up to 8-folds the strai...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 30, 2024 Category: Materials Science Authors: Nedaa Amraish Dieter H Pahr Source Type: research

Comparative studies on the anti-wear behavior of prismatic structures in different shell species
J Mech Behav Biomed Mater. 2024 Jan 24;152:106411. doi: 10.1016/j.jmbbm.2024.106411. Online ahead of print.ABSTRACTPrismatic structure is mainly located in the outer layer of mollusk shells. However, there is limited studies on their resistance to wear and the underlying mechanisms. The Vicker's hardness and sliding anti-wear properties of prismatic structures in four species of mollusk shells were systematically investigated for comparisons in the present work. The crystalline types, organic matrix content, structural arrangement, and dimension of prisms are varied among different species. The hardness and wear properties...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 28, 2024 Category: Materials Science Authors: Hongmei Ji Xin Wang Ying Yan Xiaowu Li Source Type: research

Improving early detection of keratoconus by Non Contact Tonometry. A computational study and new biomarkers proposal
This study explores the mechanical properties of keratoconic corneas through numerical simulations of non-contact tonometry (NCT) reproducing the clinical test of the Corvis ST device. Three sensitivity analyses were conducted to assess the impact of corneal material properties, size, and location of the pathological area on NCT results. Additionally, novel asymmetry-based indices were proposed to better characterize corneal deformations and improve the diagnosis of keratoconus. Our results show that the weakening of corneal material properties leads to increased deformation amplitude and altered biomechanical response. Fu...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 28, 2024 Category: Materials Science Authors: Elena Redaelli Michael Nana Bego ña Calvo Jos é Félix Rodríguez Matas Giulia Luraghi Jos Rozema Jorge Grasa Source Type: research

Tissue-mimicking composite barrier membranes to prevent abdominal adhesion formation after surgery
J Mech Behav Biomed Mater. 2024 Jan 24;152:106417. doi: 10.1016/j.jmbbm.2024.106417. Online ahead of print.ABSTRACTPostoperative abdominal adhesions often occur after abdominal surgery; barrier membranes which mimic peritoneal tissue can be constructed to prevent abdominal adhesions. To this end, silk fibroin (SF) sheets were coated with polyvinyl alcohol (PVA) and agarose (AGA) at PVA:AGA ratios of 100:0, 70:30, 50:50, 30:70, and 0:100 to create a composite anti-adhesive barrier and allow us to identify a suitable coating ratio. The membranes were characterized in terms of their molecular organization, structure, and morp...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 28, 2024 Category: Materials Science Authors: Varistha Metem Jutakan Thonglam Kantida Juncheed Matthana Khangkhamano Atichart Kwanyuang Jirut Meesane Source Type: research

Stereolithography of ceramic scaffolds for bone tissue regeneration: Influence of hydroxyapatite/silica ratio on mechanical properties
J Mech Behav Biomed Mater. 2024 Jan 24;152:106421. doi: 10.1016/j.jmbbm.2024.106421. Online ahead of print.ABSTRACTIn this paper, the results obtained in the development of ceramic resin feedstock for stereolithography are shown. Hydroxyapatite and silica are used as source of ceramic. Hydroxyapatite is extracted from bovine bone, which enhances bioactivity of ceramic scaffold. The influence of hydroxyapatite amount in polymer-based slurry on the viscosity and printability of feedstock is explored. Hydroxyapatite and silica containing scaffolds are successfully obtained by stereolithography. Influence of hydroxyapatite/sil...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 27, 2024 Category: Materials Science Authors: Viktorya Rstakyan Liana Mkhitaryan Lilit Baghdasaryan Tsovinar Ghaltaghchyan Zaruhi Karabekian Gohar Sevoyan Marina Aghayan Miguel A Rodr íguez Source Type: research

Fabrication of translucent graded dental crown using zirconia-yttrium multi-slurry tape casting 3D printer
J Mech Behav Biomed Mater. 2024 Jan 23;152:106406. doi: 10.1016/j.jmbbm.2024.106406. Online ahead of print.ABSTRACTThis paper aims to fabricate functionally graded dental crown using a multi-slurry tape casting additive manufacturing technology. The different luminescence of the dental crown was obtained with different composition of zirconia and yttria. Zirconia with tunable mechanical properties and translucency are obtained by adding 3, 3.5, 4, 4.5, and 5 mol% of yttrium oxide to zirconia powder. After obtaining the printable slurry with maximum solid loading, the green bodies are prepared using the in-house built high-...
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 27, 2024 Category: Materials Science Authors: Yulius Shan Romario Chinmai Bhat Maziar Ramezani Tim Pasang Zhangwei Chen Cho-Pei Jiang Source Type: research

Comparison of two contrast-enhancing staining agents for use in X-ray imaging and digital volume correlation measurements across the cartilage-bone interface
CONCLUSION: Hf-WD POM is a more suitable CESA solution compared to PTA for CECT imaging combined with DVC as it allowed visualisation of structural features in the cartilage tissue whilst more closely maintaining tissue mechanical properties.PMID:38277908 | DOI:10.1016/j.jmbbm.2024.106414 (Source: Journal of the Mechanical Behavior of Biomedical Materials)
Source: Journal of the Mechanical Behavior of Biomedical Materials - January 26, 2024 Category: Materials Science Authors: Sarah Davis Aikaterina Karali Tim Balcaen Jurgita Zekonyte Ma ïté Pétré Marta Roldo Greet Kerckhofs Gordon Blunn Source Type: research