Blood biomarkers improve the prediction of prevalent and incident severe chronic kidney disease
CONCLUSION: The performance improvements of CKD detection and prediction achieved by adding metabolites to traditional risk factors are modest and further research is necessary to fully understand the clinical implications of these findings.PMID:38308753 | DOI:10.1007/s40620-023-01872-w (Source: Journal of Nephrology)
Source: Journal of Nephrology - February 3, 2024 Category: Urology & Nephrology Authors: Simon Nusinovici Hengtong Li Crystal Chong Marco Yu Ida Maria Hjelm S ørensen Line Stattau Bisgaard Christina Christoffersen Susanne Bro Sylvia Liu Jian-Jun Liu Lim Su Chi Tien-Yin Wong Gavin S W Tan Ching-Yu Cheng Charumathi Sabanayagam Source Type: research

The use of burosumab to treat autosomal-recessive hypophosphatemic rickets type 2: rationale and a first clinical experience
J Nephrol. 2024 Feb 3. doi: 10.1007/s40620-023-01884-6. Online ahead of print.NO ABSTRACTPMID:38308754 | DOI:10.1007/s40620-023-01884-6 (Source: Journal of Nephrology)
Source: Journal of Nephrology - February 3, 2024 Category: Urology & Nephrology Authors: Mattia Parolin Nicola Bertazza Partigiani Elisa Benetti Germana Longo Enrico Vidal Source Type: research

Perihilar FSGS lesions originate from flat parietal epithelial cells
J Nephrol. 2024 Feb 1. doi: 10.1007/s40620-024-01886-y. Online ahead of print.NO ABSTRACTPMID:38300433 | DOI:10.1007/s40620-024-01886-y (Source: Journal of Nephrology)
Source: Journal of Nephrology - February 1, 2024 Category: Urology & Nephrology Authors: Arnaldo Chia-Gil J ürgen Floege Eleni Stamellou Marcus J Moeller Source Type: research

Diagnostic accuracy of step count as an indicator of sedentary behavior in patients with end-stage kidney disease on hemodialysis
J Nephrol. 2024 Feb 1. doi: 10.1007/s40620-023-01881-9. Online ahead of print.NO ABSTRACTPMID:38300434 | DOI:10.1007/s40620-023-01881-9 (Source: Journal of Nephrology)
Source: Journal of Nephrology - February 1, 2024 Category: Urology & Nephrology Authors: Luciana Ang élica da Silva de Jesus Bruno Valle Pinheiro B árbara Almeida Alvarenga Gabriela Ferreira Paticci é Cristino Carneiro Oliveira Leda Mar ília Fonseca Lucinda Maycon Moura Reboredo Source Type: research

A case of acute interstitial nephritis superimposed on rhabdomyolysis in a refugee patient
J Nephrol. 2024 Feb 1. doi: 10.1007/s40620-024-01895-x. Online ahead of print.NO ABSTRACTPMID:38300435 | DOI:10.1007/s40620-024-01895-x (Source: Journal of Nephrology)
Source: Journal of Nephrology - February 1, 2024 Category: Urology & Nephrology Authors: Ahmet Murt Elif Itir Sen Eren Altun Source Type: research

Predicting solute transfer rate in patients initiating peritoneal dialysis
CONCLUSIONS: An equation based on simple clinical variables allows ruling out fast transport in a significant proportion of patients initiating PD with a high degree of confidence without requiring dialysate sampling. This could prove useful in guiding dialysis prescription of PD patients in daily clinical practice, particularly in low-resource settings.PMID:38289462 | DOI:10.1007/s40620-023-01862-y (Source: Journal of Nephrology)
Source: Journal of Nephrology - January 30, 2024 Category: Urology & Nephrology Authors: David A Jaques Andrew Davenport Source Type: research

Successful wound healing by autologous peripheral blood mononuclear cell therapy in a diabetic patient on hemodialysis with no-option critical limb ischemia: a case report
We report on a limb salvage approach that was successfully employed in a 74-year-old woman on hemodialysis suffering from no-option critical limb ischemia complicated by diabetic foot infection, i.e. otherwise a candidate for major amputation. The approach consists in implanting in the wound bed of the affected limb a concentrate of autologous peripheral blood mononuclear cells collected from the peripheral blood of the patient using a selective filtration separation system. The procedure, performed by a vascular surgeon in an outpatient setting and sterile conditions, was repeated three times at intervals of 15 days, and ...
Source: Journal of Nephrology - January 30, 2024 Category: Urology & Nephrology Authors: Martina Capone Raffaele Trulli Olsi Ndrecka Lorenzo Di Liberato Mario Bonomini Source Type: research

Blood transfusion reactions and risk of acute kidney injury and major adverse kidney events
CONCLUSION: In our retrospective cohort of patients who received blood product transfusions, 25% experienced transfusion reactions, and this event was associated with a twofold increase in the probability of developing AKI and some of the major adverse kidney events during long follow-up.PMID:38285316 | DOI:10.1007/s40620-023-01859-7 (Source: Journal of Nephrology)
Source: Journal of Nephrology - January 29, 2024 Category: Urology & Nephrology Authors: Fidra Margarita De La Vega-M éndez Miguel Ibarra Estrada Esperanza Elizabeth Zuno-Reyes Carmen Alejandra Gutierrez-Rivera Ana Elisa Oliva-Martinez Bladimir D íaz-Villavicencio Clementina Elizabeth Calderon-Garcia Jose David Gonz ález-Barajas Manuel Ari Source Type: research

The unanswered question. When to undertake a maternity journey?
J Nephrol. 2024 Jan 29. doi: 10.1007/s40620-023-01865-9. Online ahead of print.NO ABSTRACTPMID:38285317 | DOI:10.1007/s40620-023-01865-9 (Source: Journal of Nephrology)
Source: Journal of Nephrology - January 29, 2024 Category: Urology & Nephrology Authors: Dalia Younis Rasha Samir Shemies Source Type: research

Residual kidney function modifies the effect of cinacalcet on serum phosphorus levels among peritoneal dialysis patients
J Nephrol. 2024 Jan 27. doi: 10.1007/s40620-023-01863-x. Online ahead of print.NO ABSTRACTPMID:38280094 | DOI:10.1007/s40620-023-01863-x (Source: Journal of Nephrology)
Source: Journal of Nephrology - January 27, 2024 Category: Urology & Nephrology Authors: Miho Murashima Naohiko Fujii Shunsuke Goto Takeshi Hasegawa Masanori Abe Norio Hanafusa Masafumi Fukagawa Takayuki Hamano Source Type: research

In memory of professor Giuseppe Maschio
J Nephrol. 2024 Jan 27. doi: 10.1007/s40620-023-01871-x. Online ahead of print.NO ABSTRACTPMID:38280095 | DOI:10.1007/s40620-023-01871-x (Source: Journal of Nephrology)
Source: Journal of Nephrology - January 27, 2024 Category: Urology & Nephrology Authors: Giovanni Gambaro Source Type: research

Outcome of atypical hemolytic uremic syndrome: role of triggers and complement abnormalities in the response to C5 inhibition
CONCLUSIONS: Our data show a better outcome in aHUS patients treated with C5-inhibition, particularly in the primary and combined forms, which have a high risk of relapse after discontinuation that is not observed in the secondary and idiopathic forms.PMID:38280096 | DOI:10.1007/s40620-023-01873-9 (Source: Journal of Nephrology)
Source: Journal of Nephrology - January 27, 2024 Category: Urology & Nephrology Authors: Gianluigi Ardissino Donata Cresseri Maria Cristina Mancuso Valentina Capone Luigi Porcaro Valeria Amico Marianna Tangredi Elena Grovetti Samantha Griffini Giuseppe Castellano Giovanni Montini Dario Consonni Massimo Cugno HUS-ItalKid Network. Source Type: research

Sarcopenia diagnosed by ultrasound-assessed quadriceps muscle thickness and handgrip strength predicts mortality in patients on hemodialysis
CONCLUSION: When combined with low handgrip strength, low quadriceps muscle US outperformed low lean tissue index as assessed by bioimpedance spectroscopy in predicting mortality in a cohort of patients on maintenance HD. Ultrasound may be a useful and convenient technique for the assessment of sarcopenia and protein-energy wasting in this patient population.PMID:38263531 | DOI:10.1007/s40620-023-01867-7 (Source: Journal of Nephrology)
Source: Journal of Nephrology - January 24, 2024 Category: Urology & Nephrology Authors: Alice Sabatino Jeroen Kooman Carla Maria Avesani Mariacristina Gregorini Stefano Bianchi Giuseppe Regolisti Enrico Fiaccadori Source Type: research

Acetazolamide for acute kidney injury in patients undergoing high dose methotrexate therapy: a systematic review and meta-analysis
CONCLUSIONS: This systematic review showed no significant difference between acetazolamide and standard care treatment regarding urine alkalinization time and AKI rate in adult patients receiving high dose methotrexate. We suggest performing a large blinded, randomized, controlled trial to evaluate the potential benefits of this low-cost medication.PMID:38265601 | DOI:10.1007/s40620-023-01850-2 (Source: Journal of Nephrology)
Source: Journal of Nephrology - January 24, 2024 Category: Urology & Nephrology Authors: Hong Hieu Truong Swetha Reddy Mariam Charkviani Nasrin Nikravangolsefid Jacob Ninan Leslie Hassett Kianoush Banaei Kashani Juan Pablo Domecq Source Type: research

NEPHRO-ZEBRA-a neonate with severe jaundice, persistent thrombocytopenia & amp; recurrent acute kidney injury later in childhood: Joining the dots!
J Nephrol. 2024 Jan 25. doi: 10.1007/s40620-023-01848-w. Online ahead of print.NO ABSTRACTPMID:38267796 | DOI:10.1007/s40620-023-01848-w (Source: Journal of Nephrology)
Source: Journal of Nephrology - January 24, 2024 Category: Urology & Nephrology Authors: Sidharth Kumar Sethi Satya P Yadav Adel Moideen Rupesh Raina Source Type: research