Similar outcomes following non-first-degree and first-degree related donor haploidentical hematopoietic cell transplantation for acute leukemia patients in complete remission: a study from the Global Committee and the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
There are situations where non-first-degree (NFD) related donors have to be considered as alternatives to first-degree (FD) related donors for haploidentical hematopoietic cell transplantation (HAPLO). However... (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - March 18, 2023 Category: Hematology Authors: Yishan Ye, Myriam Labopin, Jia Chen, Zafer Gulbas, Xi Zhang, Yener Koc, Didier Blaise, Fabio Ciceri, Emmanuelle Polge, Mohamed Houhou, Lin Li, Yi Luo, Depei Wu, He Huang, Mohamad Mohty and Norbert-Claude Gorin Tags: Correspondence Source Type: research
Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo
In this study, we analyzed the cooperati... (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - March 17, 2023 Category: Hematology Authors: Sandra Genduso, Vera Freytag, Daniela Schetler, Lennart Kirchner, Alina Schiecke, Hanna Maar, Daniel Wicklein, Florian Gebauer, Katharina Br öker, Christine Stürken, Karin Milde-Langosch, Leticia Oliveira-Ferrer, Franz L. Ricklefs, Florian Ewald, Gerrit Tags: Research Source Type: research
Involvement of inflammasomes in tumor microenvironment and tumor therapies
Inflammasomes are macromolecular platforms formed in response to damage-associated molecular patterns (DAMPs) and pathogen-associated molecular patterns, whose formation would cause maturation of interleukin-1... (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - March 17, 2023 Category: Hematology Authors: Ziqi Zhang, Xue Li, Yang Wang, Yuquan Wei and Xiawei Wei Tags: Review Source Type: research
The evolution of acute lymphoblastic leukemia research and therapy at MD Anderson over four decades
Progress in the research and therapy of adult acute lymphoblastic leukemia (ALL) is accelerating. This analysis summarizes the data derived from the clinical trials conducted at MD Anderson between 1985 and 20... (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - March 16, 2023 Category: Hematology Authors: Elias Jabbour, Nicholas J. Short, Nitin Jain, Fadi G. Haddad, Mary Alma Welch, Farhad Ravandi and Hagop Kantarjian Tags: Review Source Type: research
Glofitamab therapy for diffuse large B cell lymphoma: latest updates from the 2022 ASH Annual Meeting
Over one-third of B cell lymphomas are not effectively treated by R-CHOP chemotherapy. When lymphoma relapses or is refractory, the prognosis becomes very poor. Due to this fact, there is an urgent and clear r... (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - March 10, 2023 Category: Hematology Authors: Chaoyu Wang and Yao Liu Tags: Correspondence Source Type: research
Prognostic landscape of mitochondrial genome in myelodysplastic syndrome after stem-cell transplantation
Despite mitochondrial DNA (mtDNA) mutations are common events in cancer, their global frequency and clinical impact have not been comprehensively characterized in patients with myelodysplastic neoplasia (also ... (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - March 10, 2023 Category: Hematology Authors: Jing Dong, Christopher Staffi Buradagunta, Tao Zhang, Stephen Spellman, Yung-Tsi Bolon, Amy E. DeZern, Shahinaz M. Gadalla, H. Joachim Deeg, Aziz Nazha, Corey Cutler, Chao Cheng, Raul Urrutia, Paul Auer and Wael Saber Tags: Correspondence Source Type: research
Treatment outcomes for newly diagnosed, treatment-na ïve TP53-mutated acute myeloid leukemia: a systematic review and meta-analysis
TP53 mutations, which are present in 5% to 10% of patients with acute myeloid leukemia (AML), are associated with treatment resistance and poor outcomes. First-line therapies for TP53-mutated (TP53m) AML consist ... (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - March 6, 2023 Category: Hematology Authors: Naval G. Daver, Shahed Iqbal, Camille Renard, Rebecca J. Chan, Ken Hasegawa, Hao Hu, Preston Tse, Jiajun Yan, Michael J. Zoratti, Feng Xie and Giridharan Ramsingh Tags: Research Source Type: research
CAR T cell therapy for T cell leukemia and lymphoma: latest updates from 2022 ASH Annual Meeting
Due to the concern of fratricide, clinical development of CAR T cells for the therapy of T cell malignancies lags behind that for B cell malignancies. Attempts are being made to revise T cell biomarkers so tha... (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - March 5, 2023 Category: Hematology Authors: Qiusha Huang, Xiao-hui Zhang and Delong Liu Tags: Correspondence Source Type: research
Novel agents and regimens in acute myeloid leukemia: latest updates from 2022 ASH Annual Meeting
Developments in investigational agents and novel regimens in acute myeloid leukemia (AML) were reported in the 2022 American Society of Hematology (ASH) annual meeting. Encouraging efficacy data were presented... (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - March 3, 2023 Category: Hematology Authors: Katherine W. DiNardo, Thomas W. LeBlanc and Hui Chen Tags: Correspondence Source Type: research
Targeting STAT3-VISTA axis to suppress tumor aggression and burden in acute myeloid leukemia
The acute myeloid leukemia (AML) patients obtain limited benefits from current immune checkpoint blockades (ICBs), although immunotherapy have achieved encouraging success in numerous cancers. Here, we found t... (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - February 27, 2023 Category: Hematology Authors: Jianshan Mo, Lin Deng, Keren Peng, Shumin Ouyang, Wen Ding, Linlin Lou, Ziyou Lin, Jianzheng Zhu, Jingwei Li, Qiyi Zhang, Pengyan Wang, Yuanzhen Wen, Xiaobing Chen, Peibin Yue, Jin-Jian Lu, Kai Zhu & hellip; Tags: Correspondence Source Type: research
Broadly applicable TCR-based therapy for multiple myeloma targeting the immunoglobulin J chain
The immunoglobulin J chain (Jchain) is highly expressed in the majority of multiple myeloma (MM), and Jchain-derived peptides presented in HLA molecules may be suitable antigens for T-cell therapy of MM. (Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - February 27, 2023 Category: Hematology Authors: Miranda H. Meeuwsen, Anne K. Wouters, Tassilo L. A. Wachsmann, Renate S. Hagedoorn, Michel G. D. Kester, Dennis F. G. Remst, Dirk M. van der Steen, Arnoud H. de Ru, Els P. van Hees, Martijn Kremer, Marieke Griffioen, Peter A. van Veelen, J. H. Frederik Fa Tags: Research Source Type: research
Retraction Note: m6A mRNA methylation initiated by METTL3 directly promotes YAP translation and increases YAP activity by regulating the MALAT1-miR-1914-3p-YAP axis to induce NSCLC drug resistance and metastasis
(Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - February 22, 2023 Category: Hematology Authors: Dan Jin, Jiwei Guo, Yan Wu, Jing Du, Lijuan Yang, Xiaohong Wang, Weihua Di, Baoguang Hu, Jiajia An, Lingqun Kong, Lei Pan and Guoming Su Tags: Retraction Note Source Type: research
Correction: Olverembatinib (HQP1351), a well-tolerated and effective tyrosine kinase inhibitor for patients with T315I-mutated chronic myeloid leukemia: results of an open-label, multicenter phase 1/2 trial
(Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - February 20, 2023 Category: Hematology Authors: Qian Jiang, Zongru Li, Yazhen Qin, Weiming Li, Na Xu, Bingcheng Liu, Yanli Zhang, Li Meng, Huanling Zhu, Xin Du, Suning Chen, Yang Liang, Yu Hu, Xiaoli Liu, Yongping Song, Lichuang Men & hellip; Tags: Correction Source Type: research
Correction : LINC01123, a c-Myc-activated long non-coding RNA, promotes proliferation and aerobic glycolysis of non-small cell lung cancer through miR-199a-5p/c-Myc axis
(Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - February 18, 2023 Category: Hematology Authors: Qian Hua, Mingming Jin, Baoming Mi, Fei Xu, Tian Li, Li Zhao, Jianjun Liu and Gang Huang Tags: Correction Source Type: research
Correction: SELP Asp603Asn and severe thrombosis in COVID-19 males
(Source: Journal of Hematology and Oncology)
Source: Journal of Hematology and Oncology - February 15, 2023 Category: Hematology Authors: Chiara Fallerini, Sergio Daga, Elisa Benetti, Nicola Picchiotti, Kristina Zguro, Francesca Catapano, Virginia Baroni, Simone Lanini, Alessandro Bucalossi, Giuseppe Marotta, Francesca Colombo, Margherita Baldassarri, Francesca Fava, Giada Beligni, Laura Di Tags: Correction Source Type: research
