A Randomized, Controlled Comparison of NCX 470 (0.021%, 0.042%, and 0.065%) and Latanoprost 0.005% in Patients With Open-angle Glaucoma or Ocular Hypertension: The Dolomites Study
Conclusions:
NCX 470 demonstrated dose-dependent reductions in IOP. The 0.042% and 0.065% concentrations demonstrated significantly greater reductions from baseline in mean diurnal IOP than latanoprost 0.005% at week 4, suggesting that higher concentrations may show even greater efficacy. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - June 1, 2022 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research
Rationale and Development of an OCT-Based Method for Detection of Glaucomatous Optic Neuropathy
A specific, sensitive, and intersubjectively verifiable definition of disease for clinical care and research remains an important unmet need in the field of glaucoma. Using an iterative, consensus-building approach and employing pilot data, an optical coherence tomography (OCT)-based method to aid in the detection of glaucomatous optic neuropathy was sought to address this challenge. To maximize the chance of success, we utilized all available information from the OCT circle and cube scans, applied both quantitative and semiquantitative data analysis methods, and aimed to limit the use of perimetry to cases where it is abs...
Source: Journal of Glaucoma - June 1, 2022 Category: Opthalmology Tags: New Glaucoma Insights: Perspective Source Type: research
Home-Based Perimetry for Glaucoma: Where Are We Now?
Conclusion:
Several promising technologies designed for home-based perimetry have been reported. Current studies used a controlled setting in highly selected populations. There is uncertainty on the performance and value of home-based perimetry for glaucoma. Additional efforts are required to elucidate the ability of the home-based perimeters to detect glaucoma and disease progression in real life situations. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - June 1, 2022 Category: Opthalmology Tags: New Glaucoma Insights: Review Article Source Type: research
Response to the Letter to the Editor: Trabeculotomy Versus Combined Trabeculotomy-Trabeculectomy for Management of Primary Congenital Glaucoma
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Correspondence Source Type: research
Letter to the Editor: Trabeculotomy Versus Combined Trabeculotomy-Trabeculectomy for Management of Primary Congenital Glaucoma
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Correspondence Source Type: research
Response to the Letter to the Editor: Patient Concerns Regarding Suspended Ophthalmic Care Due to COVID-19
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Correspondence Source Type: research
Letter to the Editor: Patient Concerns Regarding Suspended Ophthalmic Care Due to COVID-19
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Correspondence Source Type: research
Smartphone Gonioscopy With a Magnifying Intraocular Lens: A Cost-effective Angle Imaging Device
In this report, the authors aim to demonstrate gonio-imaging using a smartphone attached with an intraocular lens which behaves like a macro lens. With the patient in a sitting position or in the supine position, a goniolens is placed on the patient’s cornea. A smartphone with a 10 D intraocular lens attachment over its camera is used to take images or videos of the anterior chamber angle with high magnification. This imaging modality is cost-effective and can be used for screening and photographic documentation of the angle, and can be of immense benefit, especially in primary health care centers. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Case Report Source Type: research
Glaucoma Health Coaching: A Survey of Eye Drop Instillation Education
Conclusions:
Experienced and inexperienced patients found glaucoma health coaching beneficial. Health coaching empowers patients with long-term conditions to be champions of their own health condition, and it is important for patients to receive this training from the onset of their treatment. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Trabeculotomy Versus Combined Trabeculotomy-Trabeculectomy for Management of Primary Congenital Glaucoma
Conclusion:
Trabeculotomy alone seems as effective as combined trabeculotomy-trabeculectomy and may significantly reduce exposure to anesthesia in primary congenital glaucoma patients. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Effect of Femtosecond Laser Cataract Surgery on Peripapillary Retinal Nerve Fiber Layer Thickness
Conclusions:
Both FLACS and CPCS demonstrated pRNFL thinning in some healthy eyes. Although the higher rate of pRNFL thinning after FLACS compared with CPCS lacked statistical significance, a consistent decrease in pRNFL thickness occurred in all quadrants and average pRNFL of FLACS eyes, suggesting that FLACS may lead to pRNFL thinning. Eyes with thinner preoperative pRNFL may be prone to temporal quadrant thinning after FLACS. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Clinical Outcomes of Ahmed ClearPath Implantation in Glaucomatous Eyes: A Novel Valveless Glaucoma Drainage Device
Précis:
Designed with novel features to facilitate implantation and improve safety, the Ahmed ClearPath (ACP) glaucoma drainage device (GDD) provided intraocular pressure (IOP) reduction comparable with other GDDs in eyes with refractory glaucoma in a multicenter retrospective study.
Purpose:
To present clinical outcomes with a novel valveless GDD (ACP, New World Medical). The 250 and 350 mm2 models feature a contoured plate for optimal globe apposition, anteriorized suture points to facilitate suturing to the globe, and a prethreaded 4-0 polypropylene ripcord suture.
Methods:
This was a multicenter re...
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Changing Trends in Glaucoma Surgery Over the Past 5 Years in China
Purpose:
To analyze the trends of glaucoma surgery procedures over the past 5 years among hospitals across major provinces in China.
Materials and Methods:
This was a retrospective observational study based on medical records. We obtained the annual numbers of commonly performed glaucoma incisional surgeries from 57 hospitals of 30 provincial regions in the Chinese Glaucoma Study Consortium (CGSC) from January 2015 to September 2019. The trend of glaucoma surgery was analyzed by Cochrane-Armitage trend test.
Results:
Trabeculectomy, cataract extraction combined with goniosynechialysis, cataract extraction...
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Comparison of Vision-related Quality of Life Between Normal Tension Glaucoma and Primary Open-angle Glaucoma
Conclusions:
Overall VRQOL in patients with NTG and POAG was found to be similar. However, social functioning and dependency were significantly worse in those with POAG. These findings are relevant to supporting glaucoma patients. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
The Role of Intraocular Pressure and Systemic Hypertension in the Progression of Glaucomatous Damage to the Macula
Conclusion:
Macular structural and functional parameters are more sensitive to IOP in terms of glaucomatous progression when compared with more conventional parameters. While HTN was not significantly associated with progression using any parameter, macular structural and functional parameters had a better goodness-of-fit to model progression and may be useful as endpoints. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
