Long-term Intraocular Pressure Fluctuation Is a Risk Factor for Visual Field Progression in Advanced Glaucoma
Conclusions:
Long-term IOP fluctuations and disc hemorrhage are independent and additive risk factors of visual field progression in advanced glaucoma even at low IOPs. Patients in whom these risk factors are identified require close monitoring and vigorous treatment. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Dry Eye Symptom Severity and Visual Field Reliability Metrics
Précis:
Tracking failure frequency (TFF) increases with dry eye symptom severity and in the left eye.
Purpose:
Symptoms of dry eye disease are commonly encountered in glaucoma patients and can be exacerbated by topical glaucoma medications. Dry eye disease may influence the reliability of visual field (VF) tests and impact the accurate interpretation of the results.
Patients and Methods:
Patients at the Veterans Administration Medical Center San Diego completed the 5-item Dry Eye Questionnaire before VF testing between December 2018 and February 2019. VF reliability metrics were recorded for each patient...
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Smell Sensitivity in Primary Open-angle Glaucoma and Pseudoexfoliation Glaucoma
Précis:
This cross-sectional study of 20 patients with primary open-angle glaucoma (POAG), 20 with exfoliative glaucoma (XFG), 20 with exfoliation syndrome (XS) showed that exfoliative group had a significantly lower smell identification level as compared with the control groups.
Purpose:
To investigate smell sensitivity in POAG, XFG, and XFS in comparison with healthy controls.
Materials and Methods:
This prospective, cross-sectional study included 20 patients with POAG, 20 with XFG, and 20 with XFS. The control group consisted of 20 age-matched and sex-matched healthy subjects with no evidence of ocula...
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Diagnostic Accuracy of Artificial Intelligence in Glaucoma Screening and Clinical Practice
Conclusion:
Although AI has the potential to revolutionize glaucoma care, this meta-analysis highlights that before such algorithms can be implemented into clinical care, a number of issues need to be addressed. With substantial heterogeneity across studies, many factors were found to affect the diagnostic performance. We recommend implementing a standard diagnostic protocol for grading, implementing external data validation, and analysis across different ethnicity groups. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - May 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Review Article Source Type: research
Letter to the Editor: Aerosolization During NCT Cannot Be Reliably Determined Using Air Quality Monitors: Erratum
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Erratum Source Type: research
Intermediate Outcomes of Deep Sclerectomy in Juvenile Glaucoma
Précis:
In this retrospective study of patients with predominantly severe juvenile open-angle glaucoma, deep sclerectomy (DS) achieved a success rate [defined as intraocular pressure (IOP) between 5 to 18 mm Hg] of 72% at 3 years.
Purpose:
The purpose of this study was to evaluate the safety and efficacy of DS in patients with juvenile open-angle glaucoma (JOAG).
Methods:
A retrospective chart review of all JOAG patients that underwent DS with mitomycin C at a tertiary care eye center during the period from May 2014 to May 2019.
Results:
A total of 50 eyes in 37 patients were included. The mea...
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Outcomes of Surgical Interventions in Primary Congenital Glaucoma Patients
Conclusion:
Primary trabeculotomy and primary CTT demonstrated the highest long-term success rates in PCG patients. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Early Results of Irrigating Goniectomy With TrabEx+: A Novel Device for the Treatment of Open-angle Glaucoma
Précis:
Irrigating goniectomy with the TrabEx+ device can lower intraocular pressure (IOP) in patients with glaucoma, as a standalone procedure or combined with cataract surgery.
Purpose:
The aim was to describe the efficacy and safety of irrigating goniectomy performed using the TrabEx+ device, either as a standalone procedure or combined with cataract surgery, in eyes with medically treated open-angle glaucoma.
Methods:
A retrospective case series of eyes treated by a single surgeon at a single UK teaching hospital. Data was collected at follow-up visits at 1 week, 3, 6, 12, 18, and 24 months postopera...
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Glaucoma Progression After Lens Extraction in Primary Angle-closure Glaucoma According to Angle-closure Mechanism
Conclusions:
In eyes with PACD, glaucoma progression was observed following LE despite reduced intraocular pressure. The probability of progression was highest in eyes with pupil block as a mechanism of AC. Close monitoring of glaucoma in these patients is suggested. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Structural-Functional Glaucoma Progression Trajectory in 2-Dimensional Space
Conclusion:
We present a method that presents glaucoma progression in a 2D S/F space. This approach integrates a large amount of longitudinal numerical data and provides the clinician with a rapid and intuitive summary of the patient’s glaucoma trajectory. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Wedge Defects on Optical Coherence Tomography Angiography of the Peripapillary Retina in Glaucoma: Prevalence and Associated Clinical Factors
Précis:
Among subjects with glaucoma, wedge-shaped defects on optical coherence tomography angiography (OCTA) were associated with disc hemorrhages (DH), paracentral visual field (VF) defects, increased cup-to-disc ratio (CDR), and thinner retinal nerve fiber layer (RNFL).
Purpose:
To examine determinants of wedge defects on peripapillary OCTA in glaucoma.
Materials and Methods:
A total of 278 eyes of 186 subjects with mild to severe primary open-angle glaucoma underwent 6×6 spectral-domain OCTA imaging of the superficial peripapillary retina from 2016 to 2020 at an academic practice. Wedge defects were...
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Evaluating Visual Field Progression in Advanced Glaucoma Using Trend Analysis of Targeted Mean Total Deviation
Purpose:
Trend analysis of visual field (VF) global indices may underestimate the rate of progression in severe glaucoma because of the influence of test points without detectable sensitivity. To test this hypothesis, we compared the rates of change of VF global indices with and without exclusion of undetectable points at various disease stages.
Materials and Methods:
Six hundred and forty-eight eyes of 366 glaucoma patients with 8 or more reliable 30-2 standard automated perimetry over more than 2 years were enrolled. We calculated targeted mean total deviation (TMTD) by averaging total deviation except points ...
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
The Inferior, Superior, Temporal Rim Width Pattern (IST Rule) Detects Glaucoma in a Japanese Population
Précis:
The inferior>superior>temporal rim width rate (IST pattern) rather than inferior≥superior≥nasal≥temporal (ISNT) pattern was suited for screening glaucoma in Japanese subjects. Failure of the IST pattern was associated with several important risk factors for glaucoma.
Purpose:
The purpose of this study was to find a rim width rate pattern to yield the highest positive likelihood ratio (LR+) in detecting glaucoma eyes and to identify risk factors for glaucoma correlating with its failure in a population-based setting.
Methods:
Disc stereophotographs of 2474 eyes of 2474 normal subjects and 23...
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Association of Primary Open-angle Glaucoma With Tinnitus: A Nationwide Population-Based Study
This study aims to investigate the association between primary open-angle glaucoma (POAG) and tinnitus. We found that tinnitus was significantly associated with preexisting POAG [adjusted odds ratio (OR)=1.298].
Purpose:
The purpose of this study was to investigate the association between POAG and tinnitus using nationwide population-based data from Taiwan.
Methods:
Data for this case-control study were retrieved from the Taiwan National Health Insurance Research Database for all 542,682 patients with a first-time diagnosis of tinnitus (cases), and 1,628,046 propensity score–matched controls from Taiwan’s...
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
Self-identified Black Race as a Risk Factor for Intraocular Pressure Elevation and Iritis Following Prophylactic Laser Peripheral Iridotomy
Précis:
In primary angle closure suspects (PACS), self-identified Black race was a risk factor for intraocular pressure (IOP) elevation and iritis following laser peripheral iridotomy (LPI). Laser type was not associated with either immediate post-LPI IOP elevation or iritis in multivariate analysis.
Purpose:
The aim was to determine the impact of laser type and patient characteristics on the incidence of IOP elevation and iritis after LPI in PACS.
Materials and Methods:
The electronic medical records of 1485 PACS (2407 eyes) who underwent either neodymium-doped yttrium-aluminum-garnet or sequential argo...
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Original Studies Source Type: research
