Factors Associated With Laser Trabeculoplasty Response Duration: Analysis of a Large Clinical Database (IRIS Registry)
We examined patients in a large clinical registry to assess factors associated with laser trabeculoplasty (LTP) response durations. Methods: This is a retrospective cohort study with LTP patients in the Intelligent Research in Sight Registry. Data were extracted if the eye had a LTP procedure code and a glaucoma diagnosis. In responders [≥20% intraocular pressure (IOP) reduction], any post-LTP IOP that was above 80% of baseline was considered a failure event. Eyes were censored if IOP-lowering medication/procedure was added/performed, or if the eye reached the end of follow-up. First eye of bilaterally treated pat...
Source: Journal of Glaucoma - October 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research

The Profile of Secondary Glaucoma in China: A Study of Over 10,000 Patients
This study analyzed the current profile of admitted patients with SG at the largest ophthalmic center in China. Methods: SG cases were retrieved retrospectively by International Classification of Disease-10 clinical coding data from January 2010 to December 2019. Demographic data, etiologies, and the management of SG were analyzed. The ratios of the etiologies were compared with previously reported data from other regions. The etiologies and management between the 2010 to 2014 group and the 2015 to 2019 group were compared. Results: A total of 11,730 cases were enrolled. The mean age of the patients with SG w...
Source: Journal of Glaucoma - October 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research

Comparison of the 24-2 and 24-2C Visual Field Grids in Determining the Macular Structure-Function Relationship in Glaucoma
Precis: The 24-2C grid showed significantly greater structure-function (S-F) associations in the global and regional sectors than the 24-2 visual field (VF) grid in open-angle glaucoma eyes. Purpose: The aim was to compare a Humphrey Field Analyzer (HFA) Swedish Interactive Threshold Algorithm-Faster (SITA-faster) 24-2C grid to a conventional HFA 24-2 grid regarding macular S-F relationships. Methods: The macular ganglion cell-inner plexiform layer thickness (mGCIPLT) was measured at different parafoveal sectors using spectral-domain optical coherence tomography in 150 eyes from 150 healthy, preperimetric...
Source: Journal of Glaucoma - October 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research

Lower Cognitive Function in Patients With Functionally and Structurally Severe Glaucoma: The LIGHT Study
Conclusion: Functional and structural glaucoma damage was significantly associated with lower cognitive function independent of age and visual acuity in a glaucoma cohort. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - October 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research

The Impact of Tape Sealing Face Masks on Visual Field Scores in the Era of COVID-19: A Randomized Cross-over Study
Conclusion: Tape sealing of face masks during visual field testing prevented fogging artifacts and improved visual field scores even when fogging artifacts were not obvious and should be considered in clinical practice. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - October 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research

Lessons Learned From 2 Large Community-based Glaucoma Screening Studies
Community-based screening programs have had limited success in preventing vision loss from glaucoma due to overall low prevalence of glaucoma, screening limitations, and barriers to follow-up appointments. This editorial highlights lessons learned from 2 large prospective trials: the Philadelphia Telemedicine Glaucoma Detection and Follow-up Study and the Screening To Prevent Glaucoma Study. While some lessons are specific to ophthalmology, many lessons are applicable to screening for asymptomatic diseases in underserved, vulnerable communities. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - October 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Perspective Source Type: research

Response to Letter to the Editor: Surgical Management of Pseudoexfoliative Glaucoma: A Review of Current Clinical Considerations and Surgical Outcomes
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - September 1, 2021 Category: Opthalmology Tags: Correspondence Source Type: research

Letter to the Editor: Surgical Management of Pseudoexfoliative Glaucoma: A Review of Current Clinical Considerations and Surgical Outcomes
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - September 1, 2021 Category: Opthalmology Tags: Correspondence Source Type: research

Changes in Intraocular Pressure During Hemodialysis: A Meta-analysis
Conclusions: IOP elevation in the early years of HD with the use of acetate dialysate is less of a clinical problem following its substitution with bicarbonate dialysate. However, physicians should still be cautious of potential IOP changes in the HD population with glaucoma. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - September 1, 2021 Category: Opthalmology Tags: Novel Insights: Original Studies Source Type: research

Comparison of the Prevalence and Clinical Characteristics of Epiretinal Membrane in Pseudoexfoliation and Primary Open-angle Glaucoma
Purpose: The purpose of this study was to investigate and compare the prevalence and clinical characteristics of epiretinal membrane (ERM) in patients with pseudoexfoliation glaucoma (PXG) and primary open-angle glaucoma (POAG). Methods: In this retrospective observational study, 211 PXG eyes, 210 age-matched normal eyes, and 220 POAG eyes were included. The presence and staging of ERM (stage 1, 2, and 3 or greater) were independently assessed by 2 observers. Univariate and multivariate linear regression analyses were performed to assess the factors associated with visual field (VF) mean deviation (MD) in PXG ey...
Source: Journal of Glaucoma - September 1, 2021 Category: Opthalmology Tags: Novel Insights: Original Studies Source Type: research

Twelve-Year Incidence of Open-angle Glaucoma: The Thessaloniki Eye Study
Conclusions: The incidence of OAG was similar or higher compared with other White populations. The incidence of glaucoma in those with PEX was higher compared with the incidence of glaucoma in those without PEX. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - September 1, 2021 Category: Opthalmology Tags: Novel Insights: Original Studies Source Type: research

The Agreement Between an iPad Visual Field App and Humphrey Frequency Doubling Technology in Visual Field Screening at Health Fairs
Conclusions: In this exploratory study, VFE exhibited moderate discrimination for identifying Latino adults with abnormal visual fields compared with FDT. Agreement between FDT and VFE was greater for patients with mild-to-moderate visual field loss. Further software enhancements of app-based fields testing, in concert with other portable testing, represents promising screening methods for high-risk groups in resource-limited environments. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - September 1, 2021 Category: Opthalmology Tags: Novel Insights: Original Studies Source Type: research

Circumferential Assessment of Changes in Anterior Segment Characteristics and Baseline Predictors of Angle Widening After Laser Iridotomy in Caucasian Eyes
Conclusions: LPI widened the iridocorneal angle and flattened the iris circumferentially in Caucasian eyes in this study. Baseline refractive error, lens vault, and iris volume play a significant role in the circumferential angle widening by LPI. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - September 1, 2021 Category: Opthalmology Tags: Novel Insights: Original Studies Source Type: research

Reproducibility of Retinal Nerve Fiber Layer and Macular Ganglion Cell Layer Thickness Measurements by Optical Coherence Tomography in Myopic Eyes
Precis: In myopic eyes, reproducibility of circumpapillary retinal nerve fiber layer (RNFL) and macular ganglion cell-inner plexiform layer thickness measurement by optical coherence tomography (OCT) showed excellent reproducibility except for the temporal quadrant RNFL thickness measurement. Purpose: The aim of this study was to evaluate the long-term reproducibility of circumpapillary RNFL and macular ganglion cell-inner plexiform layer (GCIPL) thickness measurements using OCT in myopic eyes. Methods: Sixty-five eyes with moderate-to-high myopia (spherical equivalent (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - September 1, 2021 Category: Opthalmology Tags: Novel Insights: Original Studies Source Type: research

Posture-induced Changes in Intraocular Pressure After Trabeculectomy in Patients With Primary Open-angle Glaucoma
Conclusion: Trabeculectomy can effectively reduce posture-induced changes in IOP in patients with POAG. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - September 1, 2021 Category: Opthalmology Tags: Novel Insights: Original Studies Source Type: research