Bilateral Acute Angle Closure Glaucoma After Prone Position Ventilation for COVID-19 Pneumonia
We report a case of bilateral acute angle closure glaucoma developing after prone position ventilation for severe COVID-19 pneumonia. A 53-year-old diabetic and hypertensive male developed blurred vision and ocular discomfort in both eyes after prone position ventilation for severe COVID-19 pneumonia. At initial examination he was noted to have diffuse corneal edema with shallow anterior chambers and mid dilated non reacting pupils. His intraocular pressure was 48 and 54 mm Hg in right and left eye, respectively. Following intravenous mannitol (20%) infusion, oral acetazolamide 250 mg 3 times daily, along with topica...
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Case Reports Source Type: research

Intraocular Pressure Variations After Intravitreal Injections Measured With an Implanted Suprachoroidal Telemetry Sensor
Conclusions: During the initial postoperative phase, IVI may cause acute reduction in IOP, either through subconjunctival leaks or increased filtration secondary to increased fluid pressure. Several months after surgery, this effect subsides and IOP spikes sharply immediately after each IVI, suggesting the resolution of the initial mechanism, most likely through scarring and fibrosis. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Case Reports Source Type: research

A Case of Endocarditis Following Endophthalmitis After XEN45 Gel Stent Implantation
We report a case of endophthalmitis and endocarditis that developed after stent perforation following a XEN45 Gel Stent implantation 10 months ago. Case Report: A 79-year-old man was referred to our hospital because of endophthalmitis of the right eye. The patient had undergone XEN45 Gel Stent implantation in the same eye 10 months ago. On examination, the conjunctiva was perforated by the stent, and it was no longer covered by the conjunctiva. A 27-G pars plana vitrectomy with intravitreal antibiotic injection was performed. Moreover, the patient received intravenous antibiotic treatment and local anti-inflammatory...
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Case Reports Source Type: research

Patient Concerns Regarding Suspended Ophthalmic Care Due to COVID-19
Purpose: The temporary cessation and profound changes in ophthalmic care delivery that occurred as a result of the coronavirus disease 2019 (COVID-19) pandemic have yet to be fully understood. Our objective is to assess patients’ self-reported impact of health care lockdown measures on their fears and anxieties during the crisis period of the COVID-19 pandemic in New York City. Methods: We conducted a digital, self-reported, patient care survey distributed by an e-mail at Columbia University’s Department of Ophthalmology outpatient faculty practice. Inclusion criteria were age greater than or equal to 18 yea...
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Quality of Life and Medical Treatment: Original Studies Source Type: research

Increased Near Activities Function Associated With Increased Glaucoma Medication Adherence Among Support, Educate, Empower (SEE) Participants
Conclusion: Better self-perceived near activities function was associated with increased glaucoma medication adherence. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Quality of Life and Medical Treatment: Original Studies Source Type: research

A Scoping Review of Quality of Life Questionnaires in Glaucoma Patients
Conclusions: Wide variability among questionnaires used to determine vision related QoL in glaucoma and in the responses elicited was identified. In conclusion, no single existing QoL questionnaire design is suitable for all purposes in glaucoma research, rather we have identified the top 10 from which the questionnaire most appropriate to the study objective may be selected. Development of a new questionnaire that could better distinguish between treatments in terms of vision and treatment-related QoL would be useful that includes the patient perspective of treatment effects as well as meeting requirements of regulato...
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Quality of Life and Medical Treatment: Original Studies Source Type: research

A Comparison of Patient Acceptance of 3 Eye Drop Instillation Aids
Conclusions: For the AutoDrop and AutoSqueeze groups, over 60% of the patients found the devices helpful and would consider using them long-term. Our results suggest that patients would be amenable to using eye drop instillation aids, although more objective data is needed to determine whether these devices would improve medication compliance and clinical outcomes. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Quality of Life and Medical Treatment: Original Studies Source Type: research

Comparison of Topical Instillation From Single-dose and Multidose Eye Drop Containers in Glaucoma: A Multicenter Randomized Cross-sectional Trial
Conclusions: These results suggest that the handling of single-use containers should be practiced by patients and evaluated by physicians, especially for the elderly population and those with advanced glaucoma. No difference in instillation quality was found between SGD and MTD. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Quality of Life and Medical Treatment: Original Studies Source Type: research

Optic Nerve Head Vessel Density Assessment in Recovered COVID-19 Patients: A Prospective Study Using Optical Coherence Tomography Angiography
Conclusions: Changes to peripapillary VD were not observed in patients with COVID-19 in the early months following diagnosis. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Vascular Biomarkers: Original Studies Source Type: research

Effects of Beta-zone Peripapillary Atrophy and Focal Lamina Cribrosa Defects on Peripapillary Vessel Parameters in Young Myopic Eyes
Precis: The development of beta-zone peripapillary atrophy (β-PPA) and focal lamina cribrosa defect (FLD) was significantly associated with decreased peripapillary optical coherence tomography angiography (OCTA) vessel parameters in young myopic eyes. Purpose: The purpose of this study was to investigate whether β-PPA and FLD affect peripapillary vessel density (VD) or perfusion density (PD) from OCTA in young myopic eyes. Materials and Methods: In a cross-sectional study, 330 eyes of 165 healthy volunteers with myopia were involved. Eyes underwent OCTA to measure peripapillary PD and VD. Eyes were grou...
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Vascular Biomarkers: Original Studies Source Type: research

Predictors of Peripapillary and Macular Optical Microangiography Measurements in Healthy Eyes
Conclusion: Significant association exists between SS of the scan and the optical coherence tomography angiography measurements generated by OMAG even when the scans have acceptable SS as recommended by the manufacturer (≥7). This needs to be considered while interpreting optical coherence tomography angiography measurements. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Vascular Biomarkers: Original Studies Source Type: research

Optical Coherence Tomography Angiography Vessel Density Changes in Normal-tension Glaucoma Treated With Carteolol, Brimonidine, or Dorzolamide
Conclusions: Topical dorzolamide possibly enhanced the VD of the peripapillary retina in NTG eyes. On the contrary, topical carteolol possibly decreased VD in the inferior-temporal peripapillary retina. Finally, in cases treated with topical brimonidine, peripapillary microcirculation remained unchanged. The study shows preliminary results and future large-scale studies are needed to confirm findings. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Vascular Biomarkers: Original Studies Source Type: research

Investigation of the Peripapillary Choriocapillaris in Normal Tension Glaucoma, Primary Open-angle Glaucoma, and Control Eyes
Precis: The peripapillary choriocapillaris (CC) was observed to be significantly impaired in normal tension glaucoma (NTG) subjects compared with normal controls using optical coherence tomography angiography (OCTA). Purpose: The aim was to quantitatively evaluate the peripapillary CC in NTG, primary open-angle glaucoma (POAG), and control eyes using OCTA. Materials and Methods: Ninety eyes (30 controls, 30 NTG, and 30 POAG) from 73 patients were imaged using the Zeiss Plex Elite 9000. Five repeat 3×3 mm OCTA scans were acquired both nasally and temporally to the optic disc and subsequently averaged. F...
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Vascular Biomarkers: Original Studies Source Type: research

Baseline Choroidal Microvasculature Dropout as a Predictor of Subsequent Visual Field Progression in Open-angle Glaucoma
Precis: Choroidal microvasculature dropout (CMvD) is an independent predictor for overall and central visual field (VF) progression in open-angle glaucoma (OAG) eyes. Purpose: The purpose of this study was to investigate the impact of CMvD identified by optical coherence tomography angiography (OCT-A) at baseline on subsequent VF progression in eyes with OAG. Methods: This retrospective observational study included 80 OAG eyes with CMvD [CMvD(+)] and without CMvD [(CMvD(−)] at baseline [40 of each matched for both age (10 y and below) and baseline VF severity (≤1 dB)]. The patients were followed r...
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Vascular Biomarkers: Original Studies Source Type: research

Relationship Between Macular Vessel Density and Total Retinal Blood Flow in Primary Open-angle Glaucoma
Precis: An association between macular vessel density (VD) and total retinal blood flow (TRBF) was demonstrated in subjects with primary open-angle glaucoma (POAG) and visual field (VF) loss. Purpose: The purpose of this study was to report relationships of macular VD metrics and TRBF in POAG. Materials and Methods: A total of 24 POAG and 19 healthy control subjects participated in the study. Subjects underwent optical coherence tomography and angiography for measurements of inner retinal thickness (IRT), VD, and spacing between large vessels (SLV) and small vessels (SSV). Doppler optical coherence tomogr...
Source: Journal of Glaucoma - August 1, 2021 Category: Opthalmology Tags: Vascular Biomarkers: Original Studies Source Type: research