COVID-19 and the Rationale for Primary Selective Laser Trabeculoplasty and Diode Laser Transscleral Cyclophotocoagulation in Africa
In this report, we provide an evidence-based discussion exploring the emerging role of lasers in Africa. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - April 1, 2022 Category: Opthalmology Tags: Advances in Glaucoma: Perspective Source Type: research
Response to Letter to the Editor: Glycerin-preserved, Human-donor, Corneoscleral Patch Grafts for Glaucoma Drainage Devices
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Correspondence Source Type: research
Response to Letter to the Editor: Cost-analysis of Surgical Intraocular Pressure Management in Glaucoma
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Correspondence Source Type: research
Letter to the Editor: Cost-analysis of Surgical Intraocular Pressure Management in Glaucoma
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Correspondence Source Type: research
Response to Letter to the Editor: Cost-analysis of Surgical Intraocular Pressure Management in Glaucoma
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Correspondence Source Type: research
Letter to the Editor: Cost-analysis of Surgical Intraocular Pressure Management in Glaucoma
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Correspondence Source Type: research
Appositional Choroidal Detachment Following XEN45 Gel Stent Requiring Surgical Drainage
An 82-year-old man with severe primary open-angle glaucoma on maximal medical therapy underwent an ab externo closed conjunctival Xen45 device insertion with mitomycin C. The surgery was uncomplicated, with a first postoperative day intraocular pressure of 4 mm Hg and visual acuity of 20/40 OD. Ten days later, the patient presented with an intraocular pressure of 5 mm Hg and a visual acuity of counting fingers at 5 feet. Examination showed Seidel negative bleb, shallow anterior chamber, and large nonappositional choroidal detachments. Medical therapy with steroids and cycloplegia was initiated. One week later, the ...
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Laboratory Science: Case Report Source Type: research
Upregulated NOTCH Signaling in the Lens of Patients With Pseudoexfoliation Syndrome Compared With Pseudoexfoliation Glaucoma Suggests Protective Role
Précis:
NOTCH signaling is significantly upregulated in the lens capsules of eyes with pseudoexfoliation syndrome (PXF) but not in those with pseudoexfoliation glaucoma (PXG) when compared with healthy controls.
Purpose:
NOTCH signaling has neuroprotective functions and altered NOTCH signaling is associated with neurodegenerative diseases with protein aggregation such as Alzheimer disease. As PXG is also a protein aggregate disease associated with neural degeneration, NOTCH molecular expression was explored in the lens capsules of patients with PXF, PXG, primary open-angle glaucoma (POAG), and healthy controls....
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Laboratory Science: Original Study Source Type: research
Long-term Results of Nd:YAG Goniopuncture on Viscocanalostomy and Phacoviscocanalostomy
Précis:
Laser goniopuncture (LGP) is an effective outpatient procedure which has been shown to maintain reduced intraocular pressure (IOP) 5 years following initial laser treatment in patients who have had viscocanalostomy (VC) (with or without phacoemulsification).
Purpose:
The purpose of this study was to establish the long term (5 y) efficacy of neodymium-doped:yttrium aluminum-garnet LGP to lower IOP following VC or phacoviscocanalostomy (PVC) in patients with glaucoma.
Patients and Methods:
This retrospective study analyzed patients who underwent LGP following VC±phacoemulsification between 2009 ...
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Clinical Science: Original Studies Source Type: research
One-Year Efficacy and Safety of the PAUL Glaucoma Implant Using a Standardized Surgical Protocol
Précis:
The PAUL Glaucoma Implant is an effective intraocular pressure (IOP)-lowering device with an acceptable safety profile. Its design as a nonvalved device with a small tube diameter using a vicryl ligation suture around the tube that is posteriorly reabsorbed instead of an ab luminal stent makes it an option in cases selected for glaucoma drainage device implantation.
Purpose:
The aim was to determine the 1-year efficacy and safety of PAUL Glaucoma Implant using a uniform, standardized surgical procedure.
Materials and Methods:
Retrospective, cohort study. Patient charts were screened between Decem...
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Clinical Science: Original Studies Source Type: research
Minimally Invasive Micro Sclerostomy (MIMS) Procedure: A Novel Glaucoma Filtration Procedure
This study set to investigate the safety, performance, and efficacy of MIMS in OAG patients.
Methods:
Prospective, open-label, single arm clinical trial with intrasubject comparisons. Study participants were adults with OAG who were candidates for a filtration procedure. Patients were operated by a single surgeon (A.A.) in Chennai, India. Following mitomycin-C pretreatment, ab interno MIMS procedure was performed alone or combined with phacoemulsification surgery. Procedure-related complications and adverse events were assessed. Primary outcomes: patients (%) achieving an intraocular pressure (IOP) ≥5 mm Hg an...
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Clinical Science: Original Studies Source Type: research
Effects of Corneal Biomechanical Properties on Rebound Tonometry (Icare200) and Applanation Tonometry (Perkins) Readings in Patients With Primary Congenital Glaucoma
Objective:
The aim was to assess the influence of corneal biomechanics on intraocular pressure (IOP) measurements made with the Icare200 (IC200) rebound tonometer and the Perkins handheld applanation tonometer in patients with primary congenital glaucoma (PCG).
Materials and Methods:
A total of 40 PCG patients and 40 healthy controls, age, and sex-matched, were recruited. IOP was measured with the Ocular Response Analyzer (IOPc, IOPg), IC200 and Perkins. The variables age, IOP, corneal hysteresis (CH), corneal resistance factor (CRF), central corneal thickness (CCT), best-corrected visual acuity, spherical equiv...
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Clinical Science: Original Studies Source Type: research
Clinical Profiles of Glaucomatous Patients With High-tension and Low-tension Optic Disc Hemorrhages: A Comparative Study
Précis:
Patients with low-tension optic disc hemorrhages (DHs) are more frequently women, have a diagnosis of normal-tension glaucoma (NTG) diagnosis and greater visual field (VF) loss. Symptoms of vascular dysregulation and Asian race also seem to be more prevalent in this clinical subtype.
Purpose:
Optic DH is an important glaucoma risk factor, and occurs in a wide intraocular pressure (IOP) range. We sought to characterize distinct clinical subtypes of patients with high-tension disc hemorrhage (HTDH) and low-tension disc hemorrhage (LTDH).
Patients and Methods:
In this cross-sectional study, treated ...
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Clinical Science: Original Studies Source Type: research
Factors Associated With Differences in the Initial Location of Structural Progression in Normal-Tension Glaucoma
Conclusions:
Different clinical factors were associated with the initial site of structural glaucoma progression in patients with NTG depending on its peripapillary or macular location, and these findings suggest possible differences in underlying mechanisms of glaucoma damage. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Clinical Science: Original Studies Source Type: research
Comparison of the Structure-Function Relationship in Glaucoma Using Optical Microangiography in the Peripapillary Retinal Nerve Fiber Layer
Conclusions:
VPD showed a stronger association with visual field loss than FI or retinal nerve fiber layer thickness except in the temporal region. The FI relationship was weak but more linear around the peripapillary region. The strength of the structure-function relationship may differ depending on the region of OMAG measurements. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - February 25, 2022 Category: Opthalmology Tags: Clinical Science: Original Studies Source Type: research
