Efficacy of Trabeculectomy Combined With Limited Deep Sclerectomy Versus Trabeculectomy Alone: A Randomized-controlled Trial
Conclusion: The addition of LDS to trabeculectomy led to lower mean IOP and higher success rates at 12 months, compared with trabeculectomy alone. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - December 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research

Comparison of Efficacy and Safety of XEN45 Implant Versus Trabeculectomy in Asian Eyes
Précis: Combined phacoemulsification and trabeculectomy is able to achieve greater reduction in intraocular pressure (IOP), higher rates of complete surgical success and fewer postoperative manipulations and visits compared with combined phacoemulsification and Xen implantation in glaucomatous eyes. Purpose: Our study aims to compare and understand the differences between the efficacy and safety of XEN45 implantation and trabeculectomy in Asian eyes with glaucoma. Materials and Methods: This was a retrospective, single-center, comparative study of consecutive patients who underwent combined phacoemulsifi...
Source: Journal of Glaucoma - December 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research

Topical Medication Adherence and Visual Field Progression in Open-angle Glaucoma: Analysis of a Large US Health Care System
Conclusions: Improving patient adherence to topical glaucoma medication may result in slower deterioration in visual function over time. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - December 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research

Agreement Analysis on Angle Characteristics With Automated Gonioscopy
Précis: Automated gonioscopy is a recent method of recording angle pictures. Our study shows that agreement between observers is moderate in most categories used in clinical practice, underlying its clinical usefulness but also room for improvement. Introduction: Iridocorneal angle (ICA) imaging methods have been recently developed to record gonioscopic images. The purpose of this study was to perform an interrater agreement analysis of ICA photographs. Methods: Multicentric cross-sectional observational study. Consecutive patients in 2 ophthalmology departments underwent automated gonioscopy. One pictur...
Source: Journal of Glaucoma - December 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research

A Decrease in Bruch’s Membrane Opening-Minimum Rim Area Precedes Decreased Retinal Nerve Fiber Layer Thickness and Visual Field Loss in Glaucoma
This study aimed to investigate the relative comparison between a decrease in BMO-MRA, the peripapillary RNFLT, and the VFI, according to the severity of glaucoma. Materials and Methods: This retrospective cross-sectional study included 121 eyes (73 with open-angle glaucoma and 48 normal eyes). The ONH and retinal nerve fiber layer were analyzed using spectral domain optical coherence tomography, and VFI was obtained using the Humphrey Field Analyzer. The tipping points of RNFLT for VFI and BMO-MRA were estimated using broken-stick regression models. Polynomial regression analysis was performed, and the changes in t...
Source: Journal of Glaucoma - December 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research

Accuracy and Reliability of Self-measured Intraocular Pressure in Glaucoma Patients Using the iCare HOME Tonometer
Conclusion: Patients trained to use the iCare HOME device can do so with fair accuracy compared with trainers with accuracy improving within 1 week of usage. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - December 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research

Intraocular Pressure Elevation Following Intravitreal Anti-VEGF Injections: Short- and Long-term Considerations
Published studies agree that transient intraocular pressure (IOP) spikes are common after intravitreal injections of anti–vascular endothelial growth factor agents. Currently, there is no standard of care guiding if and when to prevent these IOP spikes. Furthermore, there are challenges in determining the impact of postinjection IOP elevation on the health of the retinal ganglion cells, particularly given the often-existing comorbidities of retinal and glaucoma pathology. This review highlights the current literature regarding both acute and chronic postinjection IOP elevations and discusses management of postinjection I...
Source: Journal of Glaucoma - December 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Review Article Source Type: research

Letter to the Editor: Glycerin-preserved, Human-donor, Corneoscleral Patch Grafts for Glaucoma Drainage Devices
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - November 1, 2021 Category: Opthalmology Tags: Correspondence Source Type: research

Response to Letter to the Editor: Cyclodiode Laser as the First Surgical Approach in Childhood Glaucoma Under the Age of 8 Years
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - November 1, 2021 Category: Opthalmology Tags: Correspondence Source Type: research

Letter to the Editor: Cyclodiode Laser as the First Surgical Approach in Childhood Glaucoma Under the Age of 8 Years
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - November 1, 2021 Category: Opthalmology Tags: Correspondence Source Type: research

Response to Letter to the Editor: The Impacts of Face Mask Use on Standard Automated Perimetry Results in Glaucoma Patients
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - November 1, 2021 Category: Opthalmology Tags: Correspondence Source Type: research

Letter to the Editor: The Impacts of Face Mask Use on Standard Automated Perimetry Results in Glaucoma Patients
No abstract available (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - November 1, 2021 Category: Opthalmology Tags: Correspondence Source Type: research

Blue Sclera as a Complication of Micropulse Transscleral Laser Therapy
We report 3 patients who underwent micropulse laser therapy for glaucoma and subsequently developed a bluish-black discoloration of the sclera in a semicircular pattern corresponding to the probe path. This complication has not yet been reported with the micropulse laser treatment. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - November 1, 2021 Category: Opthalmology Tags: Case Report Source Type: research

Novel Bacterial Cellulose Membrane to Reduce Fibrosis Following Trabeculectomy
Purpose: The aim was to evaluate the effectiveness of bacterial cellulose membrane (BCM) in preventing fibrosis in trabeculectomy and the biocompatibility of BCM with conjunctiva and sclera. Materials and Methods: Twenty-one eyes of 21 adult rabbits underwent fornix-based trabeculectomy. Standard surgery was done to control group (CG, n=7). Mitomycin-C (MMC) (0.3 mg/mL, 3 min) was applied to MMC group only (MMCG, n=7). BCM (~100 µm thick, 10×10 mm, single layer) was covered on the sclerotomy area before conjunctiva was closed in BCM group (BCMG, n=7). Intraocular pressures (IOP) were measured before, a...
Source: Journal of Glaucoma - November 1, 2021 Category: Opthalmology Tags: Laboratory Science: Original Study Source Type: research

Effect of Prostaglandin Analogues on Corneal Biomechanical Parameters Measured With a Dynamic Scheimpflug Analyzer
Conclusion: Topical PGAs resulted in greater corneal compliance, suggesting that the changes in the corneal biomechanical properties may lead to overestimation of the intraocular pressure–lowering effects. (Source: Journal of Glaucoma)
Source: Journal of Glaucoma - November 1, 2021 Category: Opthalmology Tags: New Glaucoma Insights: Original Studies Source Type: research