An exploration of mineral density, elemental and chemical composition of primary teeth in relation to cord ‐blood vitamin D, using laboratory analysis techniques
This study used Micro-Computed Tomography (Micro-CT), Energy Dispersive X-ray analysis (EDX) and Raman spectroscopy to investigate mineral density, total density, and elemental composition of enamel and dentine in 63 exfoliated primary incisors from participants with known 25-hydroxyvitamin D levels (25-OHD) at birth. No differences in mineralisation and chemical composition using Micro-CT and EDX analysis were observed irrespective of 25-OHD status. Subtle structural differences were observed via Raman Spectroscopy, with more crystalline enamel observed in those with sufficient 25-OHD at birth. While subtle, the differenc...
Source: Journal of Bone and Mineral Research - October 26, 2023 Category: Orthopaedics Authors: Beckett DM, Vaz Viegas S, Broadbent JM, Wheeler BJ, K B ērziņš, S.J Fraser‐Miller, K.C Gordon, Drummond BK, Mahoney EK, Loch C Tags: Research Article Source Type: research

Acetyltransferases CBP/p300 control transcriptional switch of β‐catenin and Stat1 promoting osteoblast differentiation
This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - October 18, 2023 Category: Orthopaedics Authors: Linlin Zhang, Kecheng Zhu, Jingzun Xu, Xiaojing Chen, Chunxiang Sheng, Deng Zhang, Yuying Yang, Lihao Sun, Hongyan Zhao, Xiao Wang, Bei Tao, Libin Zhou, Jianmin Liu Tags: Research Article Source Type: research

Quantifying bone strength deficits in young adults born extremely preterm or extremely low birthweight
This study investigated their bone structure and estimated bone strength using peripheral quantitative computed tomography (pQCT)-based finite element modelling (pQCT-FEM). Results using this technique have been associated with bone fragility in several clinical settings. Participants comprised 161 EP/ELBW survivors (46.0% male) and 122 contemporaneous term-born (44.3% male), normal birthweight controls born in Victoria, Australia, during 1991-92. At age 25  years, participants underwent pQCT at 4% and 66% of tibia and radius length which was analysed using pQCT-FEM. Groups were compared using linear regression and adjus...
Source: Journal of Bone and Mineral Research - October 18, 2023 Category: Orthopaedics Authors: Dao T, DL Robinson, LW Doyle, PVS Lee, Olsen JE, Kale A, Cheong JLY, JD Wark Tags: Research Article Source Type: research

Association of Bone Mineral Density and Bone Turnover Markers with the Risk of Diabetes: Hong Kong Osteoporosis Study and Mendelian Randomization
This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - October 18, 2023 Category: Orthopaedics Authors: Xiaowen Zhang, Suhas Krishnamoorthy, Casey Tze ‐Lam Tang, Warrington Wen‐Qiang Hsu, Gloria Hoi‐Yee Li, Chor‐Wing Sing, Kathryn Choon‐Beng Tan, Bernard Man‐Yung Cheung, Ian Chi‐Kei Wong, Annie Wai‐Chee Kung, Ching‐Lung Cheung Tags: Research Article Source Type: research

Increased BMSi Association With Risk of Incident Osteoporotic Fractures
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - October 17, 2023 Category: Orthopaedics Authors: Adolfo Diez ‐Perez, Cristian Tebé Cordomí, Erik Fink Eriksen, Julie A. Pasco Tags: Letter to the Editor Source Type: research

Issue Information ‐ Declaration of Helsinki
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - October 16, 2023 Category: Orthopaedics Tags: Issue Information ‐ Declaration of Helsinki Source Type: research

Ed Bd, Masthead, Comm List and TOC
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - October 16, 2023 Category: Orthopaedics Tags: Issue Information Source Type: research

Journal of Bone and Mineral Research: Volume 38, Number 10, October 2023
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - October 16, 2023 Category: Orthopaedics Tags: Cover Source Type: research

Issue Information ‐ Declaration of Helsinki
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - October 16, 2023 Category: Orthopaedics Tags: Issue Information ‐ Declaration of Helsinki Source Type: research

Ed Bd, Masthead, Comm List and TOC
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - October 16, 2023 Category: Orthopaedics Tags: Issue Information Source Type: research

Journal of Bone and Mineral Research: Volume 38, Number 10, October 2023
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - October 16, 2023 Category: Orthopaedics Tags: Cover Source Type: research

Towards Improved Identification of Vertebral Fractures in Routine Computed Tomography (CT) Scans: Development and External Validation of a Machine Learning Algorithm
Vertebral fractures are the landmark of osteoporosis and are associated with increased risk of further fractures. Yet they commonly go undiagnosed, and the underlying osteoporosis untreated. We developed a machine learning algorithm for automated vertebral fracture detection and demonstrated strong performance on an external validation set of 2000 CT scans. This method can improve the identification and reporting of vertebral fractures by opportunistically screening for them in routine CT scans. ABSTRACTVertebral fractures (VFs) are the hallmark of osteoporosis, being one of the most frequent types of fragility fracture an...
Source: Journal of Bone and Mineral Research - October 16, 2023 Category: Orthopaedics Authors: Joeri Nicolaes, Michael Kriegbaum Skj ødt, Steven Raeymaeckers, Christopher Dyer Smith, Bo Abrahamsen, Thomas Fuerst, Marc Debois, Dirk Vandermeulen, Cesar Libanati Tags: Research Article Source Type: research