Journal of Bone and Mineral Research 
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.
This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Low miR ‐182‐5p Expressing Extracellular Vesicles Derived From Human Bone Marrow Stromal Cells of Subjects With Steroid‐Induced Osteonecrosis of the Femoral Head Aggravate Disease Progression
Schematic summary and conclusion of the present study. EVs derived from BMSCLesion regulate osteogenic differentiation, MAPK, and NF- κB signaling pathways by inhibiting expression of miR-182-5p, which targets MYD88 3′ UTR, resulting in inhibition of MYD88 gene expression. ABSTRACTSteroid-induced osteonecrosis of the femoral head (SONFH) is a refractory, progressive disease. However, the underlying mechanisms that aggravate femoral head necrosis remain unclear. Extracellular vesicles (EVs) act as molecular carriers in intercellular communication. We hypothesize that EVs derived from human (h) bone marrow stromal cells (...
Source: Journal of Bone and Mineral Research - May 22, 2023 Category: Orthopaedics Authors: Shushan Li,
Zhiheng Kong,
Baodong Ma,
Haitao Wang,
Yu Han,
Hongbo Zhao,
Xiangyu Shi,
Pengju Lv,
Han Yue,
Susanne Gr ässel,
Li Yin Tags: Research Article Source Type: research
Coxa Vara Deformity in Fibrous Dysplasia/McCune ‐Albright Syndrome: Prevalence, Natural History and Risk Factors: A Two‐Center Study
In conclusion, in tertiary care centers, the prevalence of FD/MAS coxa vara deformity was 36%. Risk factors included presence of MAS, high percentage of femur affected, calcar destruction, radiolucency, NSA<120 degrees and age < 15 years. © 2023 The Authors.Journal of Bone and Mineral Research published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research (ASBMR). (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - May 22, 2023 Category: Orthopaedics Authors: Maartje E. Meier,
Natasha M. Appelman ‐Dijkstra,
Michael T. Collins,
Raya E.S. Geels,
Robert P. Stanton,
Pieter Bas Witte,
Alison M. Boyce,
Michiel A.J. Sande Tags: Research Article Source Type: research
Moderate COVID ‐19 Disease Is Associated With Reduced Bone Turnover
ABSTRACTSevere acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection has been associated with musculoskeletal manifestations, including a negative effect on bone health. Bone formation was found to be reduced in coronavirus disease 2019 (COVID-19) patients. The aim of this case –control study was to determine whether bone metabolism is coupled or uncoupled in COVID-19 patients with moderately severe disease, the latter expressed by the requirement of hospitalization but not intensive care treatment, no need for mechanical ventilation, and a C-reactive protein level of (m edian [quartiles], 16.0 [4.0; 52.8]) mg/L...
Source: Journal of Bone and Mineral Research - May 19, 2023 Category: Orthopaedics Authors: Katharina Kerschan ‐Schindl,
Peter Dovjak,
Maria Butylina,
Anna Rainer,
Bernhard Mayr,
Veronika Röggla,
Helmuth Haslacher,
Michael Weber,
Galateja Jordakieva,
Peter Pietschmann Tags: Research Article Source Type: research
Is There a Causal Relationship Between Physical Activity and Bone Microarchitecture? A Study of Adult Female Twin Pairs
In conclusion, increasing PA was asso ciated with thicker cortices, larger cortical area, lower porosity of the inner transitional zone, thicker trabeculae, and smaller medullary cavities. The attenuation of cross-pair cross-trait associations after accounting for the within-individual associations were consistent with PA having a causa l effect on the improved cortical and trabecular microarchitecture of adult females, in addition to shared familial factors.This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - May 18, 2023 Category: Orthopaedics Authors: Frida Igland Nissen,
Vivienne F C Esser,
Minh Bui,
Shuai Li,
John L Hopper, Åshild Bjørnerem,
Ann Kristin Hansen Tags: Research Article Source Type: research
Association Between Combat ‐Related Traumatic Injury and Skeletal Health: Bone Mineral Density Loss Is Localized and Correlates With Altered Loading in Amputees: the Armed Services Trauma Rehabilitation Outcome (ADVANCE) Study
This article is published with the permission of the Controller of HMSO and the King's Printer for Scotland. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - May 17, 2023 Category: Orthopaedics Authors: Louise McMenemy,
Fearghal P. Behan,
Josh Kaufmann,
David Cain,
Alexander N. Bennett,
Christopher J. Boos,
Nicola T. Fear,
Paul Cullinan,
Anthony M.J. Bull,
Andrew T.M. Phillips,
Alison H. McGregor Tags: CLINICAL TRIAL Source Type: research
Relative Effects of Radiation ‐Induced Changes in Bone Mass, Structure, and Tissue Material on Vertebral Strength in a Rat Model
This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - May 16, 2023 Category: Orthopaedics Authors: Shannon R. Emerzian,
Tongge Wu,
Rachana Vaidya,
Simon Y. Tang,
Rebecca J. Abergel,
Tony M. Keaveny Tags: Research Article Source Type: research
Jump power predicts fracture risk in older adults independent of sarcopenia and FRAX
This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - May 16, 2023 Category: Orthopaedics Authors: Namki Hong,
Seung Won Burm,
Hyeon Chang Kim,
Chang Oh Kim,
Yumie Rhee Tags: Research Article Source Type: research
Single ‐cell transcriptomic atlas of parathyroid adenoma and parathyroid carcinoma
This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - May 16, 2023 Category: Orthopaedics Authors: Lihui Chen,
Ci Shan,
Shuqin Xu,
Xianzhao Deng,
Bomin Guo,
Qiong Jiao,
Li Zhang,
Youben Fan,
Hua Yue,
Zhenlin Zhang Tags: Research Article Source Type: research
Dentoalveolar Alterations in an Adenine ‐Induced Chronic Kidney Disease Mouse Model
AbstractChronic kidney disease (CKD) is characterized by kidney damage and loss of renal function. CKD mineral and bone disorder (CKD-MBD) describes dysregulation of mineral homeostasis, including hyperphosphatemia and elevated parathyroid hormone secretion, skeletal abnormalities, and vascular calcification. CKD-MBD impacts the oral cavity, with effects including salivary gland dysfunction, enamel hypoplasia and damage, increased dentin formation, decreased pulp volume, pulp calcifications, and altered jaw bones, contributing to clinical manifestations of periodontal disease and tooth loss. Underlying mechanisms are not f...
Source: Journal of Bone and Mineral Research - May 16, 2023 Category: Orthopaedics Authors: Fatma F. Mohamed,
Flavia Amadeu Oliveira,
Yuka Kinoshita,
Riti R. Yalamanchili,
Leena A. Eltilib,
Natalie L. Andras,
Sonoko Narisawa,
Takashi Tani,
Emily Y. Chu,
Jos é Luis Millán,
Brian L. Foster Tags: Research Article Source Type: research
Relative Effects of Radiation ‐Induced Changes in Bone Mass, Structure, and Tissue Material on Vertebral Strength in a Rat Model
This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - May 16, 2023 Category: Orthopaedics Authors: Shannon R. Emerzian,
Tongge Wu,
Rachana Vaidya,
Simon Y. Tang,
Rebecca J. Abergel,
Tony M. Keaveny Tags: Research Article Source Type: research
A Laplace –Hamming Binarization Approach for Second‐Generation HR‐pQCT Rescues Fine Feature Segmentation
ABSTRACTAlthough second-generation high-resolution peripheral quantitative computed tomography (XCTII) provides the highest-resolution in vivo bone microstructure assessment, the manufacturer's standard image processing protocol omits fine features in both trabecular and cortical compartments. To optimize fine structure segmentation, we implemented a binarization approach based on a Laplace –Hamming (LH) segmentation and documented the reproducibility and accuracy of XCTII structure segmentation using both the standard Gaussian-based binarization and the proposed LH segmentation approach. To evaluate reproducibility, 20 ...
Source: Journal of Bone and Mineral Research - May 13, 2023 Category: Orthopaedics Authors: Saghi Sadoughi,
Aditya Subramanian,
Gabby Ramil,
Andrew J Burghardt,
Galateia J Kazakia Tags: Research Article Source Type: research
