Exposure to multiple air pollutants and the risk of fractures: a large prospective population ‐based study
Atmospheric chemistry studies suggest air pollution impedes ultraviolet B photons and thus reduces cutaneous vitamin D3 synthesis. Biological evidence documents that inhaled pollutants disrupt circulating 25-hydroxyvitamin D [25(OH)D] metabolism and ultimately impact bone health. The hypothesis is that higher air pollution concentrations are associated with a higher risk of fractures, mediated by lower circulating 25(OH)D.The study included participants of the UK Biobank who were free of fractures history at enrollment (2006-2010) and analyzed their environmental exposure data (2007-2010). Air pollution measurements includ...
Source: Journal of Bone and Mineral Research - June 21, 2023 Category: Orthopaedics Authors: Wenhao Qi, Zhendong Mei, Zhonghan Sun, Chenhao Lin, Jinran Lin, Jialin Li, John S. Ji, Yan Zheng Tags: Research Article Source Type: research

Risk of fractures in thyroid cancer patients with postoperative hypoparathyroidism: A nationwide cohort study in Korea
This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - June 21, 2023 Category: Orthopaedics Authors: Seong Hee Ahn, You Jin Lee, Seongbin Hong, Jung Wee Park, Ye Jhin Jeon, Bit ‐Na Yoo, Yong‐Chan Ha, Jean Kyung Bak, Ha Young Kim, Young‐Kyun Lee Tags: Research Article Source Type: research

Reduced GS domain serine/threonine requirements of Fibrodysplasia Ossificans Progressiva mutant type I BMP receptor ACVR1 in the zebrafish
This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - June 18, 2023 Category: Orthopaedics Authors: Robyn S. Allen, William D. Jones, Maya Hale, Bailey N. Warder, Eileen M. Shore, Mary C. Mullins Tags: Research Article Source Type: research

Reductions in Bone Mineral Density are Apparent Early in Children with Prevalent Osteonecrosis Lesions Following Leukemia Therapy
This article is protected by copyright. All rights reserved. (Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - June 17, 2023 Category: Orthopaedics Authors: Jacqueline M Halton, Jinhui Ma, Paul Babyn, Mary Ann Matzinger, Sue C Kaste, Maya Scharke, Conrad V. Fernandez, Paivi M Miettunen, Josephine Ho, Nathalie Alos, Sharon Abish, Ronald Barr, Elizabeth Cairney, David B Dix, Ronald M Grant, Sara Tags: Research Article Source Type: research

The Multifarious Functions of Leukotrienes in Bone Metabolism
Bone profile of 5-LO-deficient mouse model. We investigated the effects of leukotrienes on bone metabolism using a 5-LO knockout mouse model. Long bones phenotype of females and males lacking 5-LO present thicker cortical bone and increased marrow area but decreased trabecular bone only in females. Osteoblasts from 5-LO KO mice show overexpression of bone formation markers leading to a decreased proliferation, and increased osteoblast differentiation and mineralization. The osteoclastogenic profile of 5-LO KO mice presents impaired osteoclasts with the downregulation of bone resorption markers and cytokines, leading to a d...
Source: Journal of Bone and Mineral Research - June 15, 2023 Category: Orthopaedics Authors: Fl ávia Amadeu de Oliveira, Cintia K. Tokuhara, Vimal Veeriah, João Paulo Domezi, Mariana R. Santesso, Tania M. Cestari, Talita M.O. Ventura, Adriana A. Matos, Thiago Dionísio, Marcel R. Ferreira, Rafael C. Ortiz, Marco A.H. Duarte, Maríli Tags: Research Article Source Type: research

Decreased Bone Density and Strength in Young People After Bariatric Surgery: How Much Matters?
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - June 14, 2023 Category: Orthopaedics Authors: Matthew A. Hornick, Michelle Van Name Tags: Editorial Source Type: research

Issue Information ‐ Declaration of Helsinki
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - June 14, 2023 Category: Orthopaedics Tags: Issue Information ‐ Declaration of Helsinki Source Type: research

Ed Bd, Masthead, Comm List and TOC
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - June 14, 2023 Category: Orthopaedics Tags: Issue Information Source Type: research

Journal of Bone and Mineral Research: Volume 38, Number 6, June 2023
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - June 14, 2023 Category: Orthopaedics Tags: Cover Source Type: research

Doubling Down on Wnt Signaling to Overcome Myeloma Bone Disease
(Source: Journal of Bone and Mineral Research)
Source: Journal of Bone and Mineral Research - June 14, 2023 Category: Orthopaedics Authors: Jes ús Delgado‐Calle, G. David Roodman Tags: Editorial Source Type: research