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Pediatric Neuroimaging Findings and Clinical Presentations of COVID-19: A Systematic Review
Since March 2020, there have been more than 770 million confirmed cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2; COVID-19) infection, according to the World Health Organization [1]. SARS-CoV-2 infection usually leads to milder symptoms in children, but about 34% develop a unique life-threatening condition known as Multisystem Inflammatory Syndrome in Children (MIS-C), Pediatric Inflammatory Multisystem Syndrome Temporally associated with COVID-19 (PIMS-TS), Systemic inflammatory syndrome in COVID-19 (SISCoV), and COVID-19-associated Kawasaki-like multisystem inflammatory syndrome (Kawa-COVID-19) 4-6 ...
Source: International Journal of Infectious Diseases - November 6, 2023 Category: Infectious Diseases Authors: Irene (Tai-Lin) Lee, Po-Jen Lin, Ho-Hsian Yen Source Type: research

Comparison of Dalbavancin with standard of care in the management of infective endocarditis: efficacy, safety, and cost analysis
Dalbavancin is a lipoglycopeptide antibiotic that has a lipophilic side chain that gives it a long half-life, allowing weekly or every two weeks administration [1 –3]. It has been approved for the treatment of skin and soft tissue infections [2]. Its innovative posology could offer great advantages in the consolidation treatment of infections that require prolonged antibiotic treatment, such as infective endocarditis (IE), and osteoarticular infection [3– 5]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - November 4, 2023 Category: Infectious Diseases Authors: M Su árez, A Pérez-Landeiro, A Sanjurjo, O. Lima, A. Sousa, A. López, L. Martínez-Lamas, X. Cabrera, M Rubianes, MT Pérez-Rodríguez Source Type: research

Favorable outcome without corticosteroids during post-artesunate delayed hemolysis with positive direct antiglobulin test in severe imported Plasmodium falciparum malaria, France
Post-artesunate delayed hemolysis (PADH) is a common nonrecurring adverse effect of artesunate during severe Plasmodium falciparum malaria, which occurs after the first week of treatment in an estimated 10-30% of cases in nonimmune travelers [1,2]. Reports of positive direct antiglobulin tests (DAT) in patients experiencing PADH suggest an immune-driven process [1,3]. In a systematic review, 44% of patients with PADH had a positive DAT [4]. Most previous reports focused only on patients experiencing PADH and not on other patients with severe malaria. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - November 3, 2023 Category: Infectious Diseases Authors: Olivier Paccoud, Xavier Chamillard, Eric Kendjo, Isabelle Vinatier, Laure Surgers, Denis Magne, Benjamin Wyplosz, Ad éla Angoulvant, Olivier Bouchaud, Arezki Izri, Sophie Matheron, Sandrine Houzé, Marc Thellier, Alioune P. Ndour, Pierre Buffet, Eric Cau Tags: Short Communication Source Type: research

Favorable outcome without corticosteroids during Post-Artesunate Delayed Haemolysis with positive Direct Antiglobulin Test in severe imported Plasmodium falciparum malaria, France
Post-artesunate delayed haemolysis (PADH) is a common non-recurring adverse effect of artesunate during severe P.falciparum malaria, which occurs after the first week of treatment in an estimated 10-30% of cases in non-immune travelers [1,2]. Reports of positive direct antiglobulin tests (DAT) in patients experiencing PADH suggest an immune-driven process [1,3]. In a systematic review, 44% of patients with PADH had a positive DAT [4]. Most prior reports focused only on patients experiencing PADH and not other patients with severe malaria. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - November 3, 2023 Category: Infectious Diseases Authors: Olivier Paccoud, Xavier Chamillard, Eric Kendjo, Isabelle Vinatier, Laure Surgers, Denis Magne, Benjamin Wyplosz, Ad éla Angoulvant, Olivier Bouchaud, Arezki Izri, Sophie Matheron, Sandrine Houzé, Marc Thellier, Alioune P. Ndour, Pierre Buffet, Eric Cau Tags: Short Communication Source Type: research

Contemporary use of cefazolin for MSSA infective endocarditis: Analysis of a national prospective cohort
Infective endocarditis (IE) is a life-threatening infectious disease characterized by its high morbimortality [1,2]. Today, Staphylococcus aureus is the most common cause of IE in developed countries[3,4] with a growing incidence in the last decades due to its relationship with health-care contact[1,3]. Particularly, S. aureus IE has been associated with immunosuppression, prosthetic cardiac devices, hemodialysis and other invasive procedures [3,4], as well as an aggressive presentation and poor prognosis[5]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - November 3, 2023 Category: Infectious Diseases Authors: L. Herrera-Hidalgo, P. Mu ñoz, A. Álvarez-Uría, D. Alonso-Menchén, R. Luque-Marquez, E. Gutiérrez-Carretero, MC. Fariñas, JM. Miró, MA Goenaga, LE. López-Cortés, B. Angulo-Lara, L. Boix-Palop, Arístides de Alarcón, Grupo de Apoyo al Manejo de l Source Type: research

The frequency of SARS-CoV-2 infection/vaccination-related chorea depends on the inclusion/exclusion criteria
We read with interest the article by Rosca et  al. [1] about a review of 14 patients with chorea after SARS-CoV-2 infection (SC2I) and eight patients with chorea after SARS-CoV-2 vaccination (SC2V). The pathophysiology underlying the development of chorea has been explained by the immune response to the infection, by direct damage related to t he infectious agent, or by infection-related complications [1]. The study is impressive, but several points require discussion. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - November 1, 2023 Category: Infectious Diseases Authors: Josef Finsterer, Fulvio A. Scorza Tags: Letter to the Editor Source Type: research

The frequency of SARS-CoV-2 infection/vaccination-related chorea depends on the inclusion/exclusion criteria – author's reply
We appreciate comments brought forth by Finsterer and Scorza regarding our previous publication [1], with main concerns related to the included cases. We acknowledge that the lack of standardized reporting and the quality of information in included reports limit our findings [1]. We did not formally assess the methodological quality of the studies [2], as scoping reviews allow a synopsis of evidence, disregarding the risk of bias [2,3]. However, we provided key clinical findings. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - November 1, 2023 Category: Infectious Diseases Authors: Elena Cecilia Rosca, Raluca Bilavu, Amalia Cornea, Mihaela Simu Tags: Letter to the Editor Source Type: research

Long-term Prognosis at 1.5 years after Infection with Wild-type strain of SARS-CoV-2 and Alpha, Delta, as well as Omicron Variants
More than three years after the first COVID-19 cases, several patients suffer from post-infectious health effects called long COVID [1, 2]. These sequelae have been defined as symptoms persisting more than 3 months after initial COVID-19 [3]. Fatigue, concentration difficulties, shortness of breath, and myalgia are among the numerous symptoms associated with long COVID [1, 4, 5]. It was early documented, that Omicron infection resulted in a milder acute course compared to previous variants [6], and understanding the risk and the characteristics of long COVID symptoms following changing variants has been of great interest f...
Source: International Journal of Infectious Diseases - October 29, 2023 Category: Infectious Diseases Authors: Jane Agergaard, Jesper Damsgaard Gunst, Berit Schi øttz-Christensen, Lars Østergaard, Christian Wejse Source Type: research

Characterizing the evolving SARS-CoV-2 seroprevalence in urban and rural Malawi between February 2021 and April 2022: A population-based cohort study
Malawi, one of the lowest-income countries in Africa [1], has experienced four waves of COVID-19 in the first 2 years of the pandemic; June-August 2020 (wave 1, likely ancestral), December 2020-April 2021 (wave 2, Beta) June-September 2021 (wave 3, Delta) and December 2021-January 2022 (wave 4, Omicron BA.1/2; Figure  1) [2]. Due to limited SARS-CoV-2 testing [3] and surveillance, in addition to a high proportion of asymptomatic infections, the number of confirmed cases likely substantially underestimates the true burden of COVID-19 in Malawi, even more so than in other settings. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 27, 2023 Category: Infectious Diseases Authors: Louis Banda, Antonia Ho, Stephen Kasenda, Jonathan M. Read, Chris Jewell, Alison Price, Estelle McLean, Albert Dube, David Chaima, Lyson Samikwa, Tonney S. Nyirenda, Ellen C. Hughes, Brian J. Willett, Annie Chauma Mwale, Abena S. Amoah, Amelia Crampin Source Type: research

Characterising the evolving SARS-CoV-2 seroprevalence in urban and rural Malawi between February 2021 and April 2022: a population-based cohort study
Malawi, one of the lowest income countries in Africa [1], has experienced four waves of COVID-19 in the first two years of the pandemic; June-August 2020 (wave 1, likely ancestral), December 2020-April 2021 (wave 2, Beta) June-September 2021 (wave 3, Delta) and December 2021-January 2022 (wave 4, Omicron BA.1/2; Figure 1) [2]. Due to limited SARS-CoV-2 testing [3] and surveillance, in addition to a high proportion of asymptomatic infections, the number of confirmed cases likely substantially underestimates the true burden of COVID-19 in Malawi, even more so than in other settings. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 27, 2023 Category: Infectious Diseases Authors: Louis Banda, Antonia Ho, Stephen Kasenda, Jonathan M Read, Chris Jewell, Alison Price, Estelle McLean, Albert Dube, David Chaima, Lyson Samikwa, Tonney S Nyirenda, Ellen C Hughes, Brian J Willett, Annie Chauma Mwale, Abena S Amoah, Amelia Crampin Source Type: research

Editorial Board
(Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 24, 2023 Category: Infectious Diseases Source Type: research

Description of mpox reinfection by whole genome sequencing
Mpox was recognized as a public health emergency of international concern after a multi-country outbreak was identified in May 2022. The efficacy of the attenuated vaccinia virus vaccine in preventing mpox is not well established, and robust data are not yet available regarding the durability of cross-immunity after natural mpox infection, as a low proportion of mpox-neutralizing antibodies have been detected in individuals with past mpox [1,2]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 24, 2023 Category: Infectious Diseases Authors: Javier Mart ínez-Sanz, Manuel Ponce, Laura Martínez-García, Víctor de la Cueva, Leticia Olavarrieta, Laura Montero, María Jesús Pérez-Elías, Juan Carlos Galán Tags: Case Report Source Type: research

Community Health Workers in clinical research at the example of a phase IIIb/ IV antimalarial drug trial conducted in five African countries
Malaria is a parasitic disease transmitted by infected Anopheles mosquitoes. Despite the over a century long history of control and elimination efforts, malaria still represents an important disease burden, particularly for sub-Saharan Africa.[1] New tools and interventions like insecticide treated bed nets or the introduction of artemisinin-based combination therapies have contributed importantly to the progress towards malaria elimination and eradication since the beginning of the millennium. Notwithstanding, this progress has stalled since 2015 and the 2020 milestones of the “Global Technical Strategy For Malaria” s...
Source: International Journal of Infectious Diseases - October 20, 2023 Category: Infectious Diseases Authors: Mirjam Groger, Gaston Tona Lutete, Serge-Brice Assi, Jude D. Bigoga, Nsengi Y. Ntamabyaliro, Sarah Arbe-Barnes, Jangsik Shin, Ayola A. Adegnika, Francine Ntoumi, Peter G. Kremsner, Michael Ramharter, Stephan Duparc, Isabelle Borghini-Fuhrer, Ghyslain Momb Tags: Perspective Source Type: research

Age, successive waves, immunization, and mortality in elderly COVID-19 hematological patients: EPICOVIDEHA findings
The impact of the SARS-CoV-2 pandemic has caused excess mortality worldwide. Its severity and clinical consequences varied according to differences in the characteristics of infected subjects. Both, age [1] and hematologic malignancy [2 –17] proved to be adverse prognostic factors in most studies reported, making elderly patients affected by hematological malignancy among the categories of patients most vulnerable to severe infection. A better knowledge of the clinical characteristics of COVID-19 [18] together with the availabili ty of effective prophylactic and therapeutic agents and the benefits of widespread vaccinati...
Source: International Journal of Infectious Diseases - October 18, 2023 Category: Infectious Diseases Authors: Giuseppe Rossi, Jon Salmanton-Garc ía, Chiara Cattaneo, Francesco Marchesi, Julio Dávila-Valls, Sonia Martín-Pérez, Federico Itri, Alberto López-García, Andreas Glenthøj, Maria Gomes da Silva, Caroline Besson, Monia Marchetti, Barbora Weinbergerov� Source Type: research

Transmission dynamics and phylogeography of Mycobacterium tuberculosis in China based on whole-genome phylogenetic analysis
China has continued to experience one of the most serious tuberculosis (TB) endemics worldwide [1]. In the past few decades, China has made significant achievements in TB epidemic control [2], but the overall incidence of pulmonary TB has not decreased significantly [3]. The relative contribution of recent transmission to TB prevalence in China remains unclear. Meanwhile, progress in TB transmission control has been slow, as little is known about how transmission occurs, how strain-specific features affect transmission, and the paths of countrywide transmission. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 18, 2023 Category: Infectious Diseases Authors: Yi-fan Li, Yang Yang, Xiang-long Kong, Wan-mei Song, Ya-meng Li, Ying-Ying Li, Wei-wei Fang, Jie-yu Yang, Dan Men, Chun-Bao Yu, Guo-ru Yang, Wen-ge Han, Wen-yu Liu, Kun Yan, Huai-chen Li, Yao Liu Source Type: research