Transmission dynamics and phylogeography of Mycobacterium tuberculosis in China based on whole-genome phylogenetic analysis

China has continued to experience one of the most serious tuberculosis (TB) endemics worldwide [1]. In the past few decades, China has made significant achievements in TB epidemic control [2], but the overall incidence of pulmonary TB has not decreased significantly [3]. The relative contribution of recent transmission to TB prevalence in China remains unclear. Meanwhile, progress in TB transmission control has been slow, as little is known about how transmission occurs, how strain-specific features affect transmission, and the paths of countrywide transmission.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research