Stochastic Interventional Approach to Assessing Immune Correlates of Protection: Application to the COVE mRNA-1273 Vaccine Trial
: SVE analysis of COVE supports nAb titer as a CoP for mRNA vaccines. Predicting variant-specific VE proved difficult due to many limitations. Greater anti-Omicron titers may be needed for high-level protection against Omicron vs. anti-D614G titers needed for high-level protection against pre-Omicron COVID-19. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 9, 2023 Category: Infectious Diseases Authors: Nima S. Hejazi, Xiaoying Shen, Lindsay N. Carpp, David Benkeser, Dean Follmann, Holly E. Janes, Lindsey R. Baden, Hana M. El Sahly, Weiping Deng, Honghong Zhou, Brett Leav, David C. Montefiori, Peter B. Gilbert Source Type: research

Epidemiology, genetic characteristics, and association with meteorological factors of human metapneumovirus infection in children in southern China: A 10-year retrospective study
Acute respiratory tract infections (ARIs) are common global diseases that can cause pneumonia and death in adults and children [1]. According to the Pneumonia Etiology Research for Child Health (PERCH) study reports, 61.4% of severe childhood pneumonia is attributed to respiratory virus infections. Among these viruses, human metapneumovirus (HMPV) is one of the most common viruses that causes ARIs and leads to pneumonia [2]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 7, 2023 Category: Infectious Diseases Authors: Hengming Ye, Shuqing Zhang, Kexin Zhang, Yizhe Li, Delin Chen, Yongyao Tan, Linyue Liang, Minjie Liu, Jingyao Liang, Shu An, Jueheng Wu, Xun Zhu, Mengfeng Li, Zhenjian He Source Type: research

Epidemiology, genetic characteristics and association with meteorological factors of human metapneumovirus infection in children in southern China: a ten-year retrospective study
Acute respiratory tract infections (ARIs) are common global diseases that can cause pneumonia and death in adults and children [1]. According to the Pneumonia Etiology Research for Child Health (PERCH) Study reports, 61.4% of severe childhood pneumonia is attributed to respiratory virus infections. Among these viruses, human metapneumovirus (HMPV) is one of the most common viruses that causes ARIs and leads to pneumonia [2]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 7, 2023 Category: Infectious Diseases Authors: Hengming Ye, Shuqing Zhang, Kexin Zhang, Yizhe Li, Delin Chen, Yongyao Tan, Linyue Liang, Minjie Liu, Jingyao Liang, Shu An, Jueheng Wu, Xun Zhu, Mengfeng Li, Zhenjian He Source Type: research

Global prevalence of respiratory virus infections in adults and adolescents during the COVID-19 pandemic: A systematic review and meta-analysis
At the end of 2019, first cases of the previously unknown severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged[1]. The virus spread rapidly, prompting the World Health Organization (WHO) to characterise the outbreak as a pandemic on March 11, 2020[2]. Various non-pharmaceutical interventions were implemented to mitigate the transmission of the virus [3]. The measures aimed to target transmission routes of the SARS-CoV-2 such as the inhalation of droplets/aerosols, physical contact with infected individuals and indirect transmission through contaminated surfaces. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 6, 2023 Category: Infectious Diseases Authors: Marit L. Sch üz, Leonie Dallmeyer, Paraskevi C. Fragkou, Jimmy Omony, Hanna Krumbein, Ben L. Hünerbein, Chrysanthi Skevaki Source Type: research

Implications of asymptomatic malaria infections on hematologic parameters in adults living with HIV in malaria-endemic regions with varying transmission intensities
HIV and malaria remain important global health concerns with major public health implications; these two infections have considerable geographical overlap with substantial co-infection occurring in sub-Saharan Africa (sSA) [1]. HIV and malaria infections have clinical, diagnostic, and therapeutic interactions, with HIV infection affecting the immune response to malaria, particularly in adolescents and adults, and for pregnancy-specific immunity [2]. This leads to different patterns of disease in people living with HIV (PLHIV) compared to people living without HIV (PLWoH) [3]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 1, 2023 Category: Infectious Diseases Authors: Edwin Kamau, Risper Maisiba, Nicole Dear, Allahna Esber, Ajay P. Parikh, Michael Iroezindu, Emmanuel Bahemana, Hannah Kibuuka, John Owuoth, Jonah Maswai, Benjamin Opot, Raphael O. Okoth, Farid Abdi, Maureen Mwalo, Dennis Juma, Ben Andagalu, Hoseah M. Akal Source Type: research

Progressive multifocal leukoencephalopathy triggered by COVID-19 in a previously asymptomatic person living with undiagnosed HIV infection
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the central nervous system (CNS) caused by the human polyomavirus 2 (HPyV-2), previously known as John Cunningham Virus. [1,2]. Historically, PML has been categorized into three temporal epidemiological phases. The first phase predates the human immunodeficiency virus (HIV), and is mainly related to organ transplantation, hematologic malignancies, or use of immunosuppressive medications. The second phase marks the appearance of HIV in 1981, showing a significant increase, and its identification as a defining disease of acquired immunodeficiency ...
Source: International Journal of Infectious Diseases - October 1, 2023 Category: Infectious Diseases Authors: Yago Marcos Pessoa Gon çalves, Thaís Soares Farnesi de Assunção, Marlos Aureliano Dias de Sousa, Luis Marcos Ferreira, Beatriz Sodré Matos, Anna Victória Bernardes e Borges, Ana Carolina de Morais Oliveira Scussel, Alex Eduardo da Silva, Carlo José Tags: Case Report Source Type: research

Implications of asymptomatic malaria infections on hematological parameters in adults living with HIV in malaria endemic regions with varying transmission intensities
Hematological parameters are important indicators of health and disease. In PLHIV with asymptomatic malaria coinfection enrolled across four geographic sites in three African countries, abnormalities in hematologic parameters differ in different malaria transmission settings and are region specific. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 1, 2023 Category: Infectious Diseases Authors: Edwin Kamau, Risper Maisiba, Nicole Dear, Allahna Esber, Ajay P. Parikh, Michael Iroezindu, Emmanuel Bahemana, Hannah Kibuuka, John Owuoth, Jonah Maswai, Benjamin Opot, Raphael O. Okoth, Farid Abdi, Maureen Mwalo, Dennis Juma, Ben Andagalu, Hoseah M. Akal Source Type: research

Secondary household transmission of SARS-CoV-2: A case-control study on factors associated with reduced transmission risk
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is primarily transmitted through respiratory droplets, saliva, fomites, and aerosols resulting from direct or indirect contact with infected individuals. The risk of person-to-person transmission is particularly high in crowded or poorly ventilated spaces, or during prolonged exposure to an infected person [1]. The household environment exemplifies such conditions. When one household member tested positive for SARS-CoV-2, the risk of to family members increased due to their close contact. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - October 1, 2023 Category: Infectious Diseases Authors: Masato Inaba, Yukiko Miyake, Kazutaka Yasuda Tags: Short Communication Source Type: research

Antiviral combination therapies for persistent COVID-19 in immunocompromised patients
As a paradigm for difficult-to-treat microorganisms, many chronic viral infections require combination therapy with direct-acting antivirals (DAA) employing different mechanisms of action (MOA) for successful eradication (e.g., hepatitis C virus, HIV and influenza). (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - September 29, 2023 Category: Infectious Diseases Authors: Daniele Focosi, Fabrizio Maggi, Alessandra D'Abramo, Emanuele Nicastri, David J Sullivan Tags: Review Source Type: research

Antiviral combination therapies for persistent COVID-19 in immunocompromised patients.
As a paradigm for difficult-to-treat microorganisms, many chronic viral infections require combination therapy with direct-acting antivirals (DAA) employing different mechanisms of action (MOA) for successful eradication (e.g., HCV, HIV and influenza). (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - September 29, 2023 Category: Infectious Diseases Authors: Daniele Focosi, Fabrizio Maggi, Alessandra D'Abramo, Emanuele Nicastri, David J Sullivan Tags: Review Source Type: research

Corrigendum to “Colorimetric detection of SARS-CoV-2 by uracil-DNA glycosylase (UDG) reverse transcription loop-mediated isothermal amplification (RT-LAMP)” [International Journal of Infectious Diseases 120 (2023) Pages 132-134]
The authors regret the Acknowledgement statement was incorrect in the published version of this article. The correct Acknowledgement statement is as follows: (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - September 28, 2023 Category: Infectious Diseases Authors: Meng Yee Lai, Fatma Diyana Mohd Bukhari, Nur Zulaikha Zulkefli, Ilyiana Ismail, Nur Izati Mustapa, Tuan Suhaila Tuan Soh, Afifah Haji Hassan, Kalaiarasu M Peariasamy, Yee Leng Lee, Jeyanthi Suppiah, Ravindran Thayan, Yee Ling Lau Tags: Corrigendum Source Type: research

Toward political economy of sustainable financing for immunization in the World Health Organization African Region through a systems thinking lens
Routine childhood immunization is considered one of the most effective public health interventions in the world because of its impact on child morbidity and mortality [1]. According to the United Nations Children's Fund (UNICEF), routine immunization averts about 4.4 million child deaths globally per year [2]. Studies have shown that routine childhood immunization also has high economic benefit and yields significant social returns [3]. Using the value-of-a-statistical life method, the return on investment (ROI) of routine childhood immunization in low- and middle-income countries in the “decade of vaccines” was estima...
Source: International Journal of Infectious Diseases - September 27, 2023 Category: Infectious Diseases Authors: Abdu A Adamu, T éné-Alima Essoh, Rabiu I Jalo, Charles S Wiysonge Tags: Perspective Source Type: research

Towards Political Economy of Sustainable Financing for Immunization in the WHO African Region through a Systems Thinking Lens
Routine childhood immunization is considered one of the most effective public health interventions in the world because of its impact on child morbidity and mortality [1]. According to the United Nations Children's Fund (UNICEF), routine immunization averts about 4.4 million child deaths globally per year [2]. Studies have shown that routine childhood immunization also has high economic benefit and yields significant social returns [3]. Using the value-of-a-statistical life method, the return on investment (ROI) of routine childhood immunization in low- and middle-income countries in the “decade of vaccines” was estima...
Source: International Journal of Infectious Diseases - September 27, 2023 Category: Infectious Diseases Authors: Abdu A Adamu, T éné-Alima Essoh, Rabiu I Jalo, Charles S Wiysonge Tags: Perspective Source Type: research

Editorial Board
(Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - September 26, 2023 Category: Infectious Diseases Source Type: research

TNFAIP3-interacting protein 1 polymorphisms and their association with symptomatic human respiratory syncytial virus infection and bronchiolitis in infants younger than one year from South Africa: A case-control study
Human respiratory syncytial virus (HRSV) can cause severe diseases such as bronchiolitis and pneumonia in specific vulnerable populations, such as infants [1]. Bronchiolitis is the most common severe HRSV-related disease in infants, characterized by inflammation of the bronchioles, mucus production, and subsequent airway obstruction. An excessive inflammatory response has been related to HRSV pathogenesis, but also a robust innate immune response is needed to control virus replication and protect against severe HRSV disease [2]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - September 24, 2023 Category: Infectious Diseases Authors: Mar ía Martin-Vicente, Hloni Mthiyane, María A Jiménez-Sousa, Kathleen Subramoney, Orienka Hellferscee, Nicole Wolter, Sibongile Walaza, Amanda Fernández-Rodríguez, Cheryl Cohen, Anne von Gottberg, Salvador Resino, Isidoro Martínez, Florette K Treur Tags: Short Communication Source Type: research