TNFAIP3-interacting protein 1 polymorphisms and their association with symptomatic human respiratory syncytial virus infection and bronchiolitis in infants younger than one year from South Africa: A case-control study

Human respiratory syncytial virus (HRSV) can cause severe diseases such as bronchiolitis and pneumonia in specific vulnerable populations, such as infants [1]. Bronchiolitis is the most common severe HRSV-related disease in infants, characterized by inflammation of the bronchioles, mucus production, and subsequent airway obstruction. An excessive inflammatory response has been related to HRSV pathogenesis, but also a robust innate immune response is needed to control virus replication and protect against severe HRSV disease [2].

Source: International Journal of Infectious Diseases - September 24, 2023 Category: Infectious Diseases Authors: Mar ía Martin-Vicente, Hloni Mthiyane, María A Jiménez-Sousa, Kathleen Subramoney, Orienka Hellferscee, Nicole Wolter, Sibongile Walaza, Amanda Fernández-Rodríguez, Cheryl Cohen, Anne von Gottberg, Salvador Resino, Isidoro Martínez, Florette K Treur Tags: Short Communication Source Type: research