Herpes Zoster Burden of Disease and Clinical Management in Turkey: A Comprehensive Literature Review
ConclusionOverall, there were limited comprehensive epidemiological data on HZ in Turkey. However, the abundance of case studies on HZ complications indicates a strong disease presence and diverse clinical management in Turkey. Further research will be important to understand the impact of HZ, increase disease awareness, and support the introduction of new preventative strategies. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - August 2, 2023 Category: Infectious Diseases Source Type: research
Increasing of New CA-MRSA Infections Detected in people living with HIV Who Engage in Chemsex in Barcelona: An Ambispective Study
ConclusionPLWH who engage in chemsex may present with CA-MRSA infections. Clinical suspicion and microbiological diagnosis are required to provide adequate therapy, and CA-MRSA prevention interventions should be designed. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - July 26, 2023 Category: Infectious Diseases Source Type: research
Is Azvudine Comparable to Nirmatrelvir-Ritonavir in Real-World Efficacy and Safety for Hospitalized Patients with COVID-19? A Retrospective Cohort Study
ConclusionAzvudine probably possessed comparable efficacy and safety to nirmatrelvir-ritonavir, although it was less effective than nirmatrelvir-ritonavir for some outcomes.Graphical Abstract (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - July 24, 2023 Category: Infectious Diseases Source Type: research
Assessment of Drug –Drug Interaction Risk Between Intravenous Fentanyl and the Glecaprevir/Pibrentasvir Combination Regimen in Hepatitis C Patients Using Physiologically Based Pharmacokinetic Modeling and Simulations
ConclusionThe administration of a therapeutic dose of GLE/PIB has very little effect on the pharmacokinetics of intravenous fentanyl. This negligible increase would not be expected to increase the risk of fentanyl overdose beyond the inherent risks related to the amount and purity of the fentanyl received during recreational use. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - July 20, 2023 Category: Infectious Diseases Source Type: research
Applying Rituximab During the Conditioning Regimen Prevents Epstein –Barr Virus Infection Following Allogeneic Hematopoietic Stem Cell Transplant in a Children’s Cohort: A Retrospective Case–Control Study
ConclusionsThe administration of rituximab before HSCT may prevent EBV infection following HSCT. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - July 20, 2023 Category: Infectious Diseases Source Type: research
Assessment of Drug –Drug Interaction Risk Between Intravenous Fentanyl and the Glecaprevir/Pibrentasvir Combination Regimen in Hepatitis C Patients Using Physiologically Based Pharmacokinetic Modeling and Simulations
ConclusionThe administration of a therapeutic dose of GLE/PIB has very little effect on the pharmacokinetics of intravenous fentanyl. This negligible increase would not be expected to increase the risk of fentanyl overdose beyond the inherent risks related to the amount and purity of the fentanyl received during recreational use. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - July 20, 2023 Category: Infectious Diseases Source Type: research
Applying Rituximab During the Conditioning Regimen Prevents Epstein –Barr Virus Infection Following Allogeneic Hematopoietic Stem Cell Transplant in a Children’s Cohort: A Retrospective Case–Control Study
ConclusionsThe administration of rituximab before HSCT may prevent EBV infection following HSCT. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - July 20, 2023 Category: Infectious Diseases Source Type: research
Cabotegravir and Rilpivirine Long-Acting Antiretroviral Therapy Administered Every 2 Months is Cost-Effective for the Treatment of HIV-1 in Spain
ConclusionFrom the Spanish National Health System perspective, CAB+RPV LA Q2M is a cost-effective alternative compared with the current options of daily oral STR regimens for HIV treatment.Clinical Trials RegistrationATLAS, NCT02951052; ATLAS-2M, NCT03299049; FLAIR, NCT02938520. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - July 14, 2023 Category: Infectious Diseases Source Type: research
Highly Resistant Serotype 19A Streptococcus pneumoniae of the GPSC1/CC320 Clone from Invasive Infections in Poland Prior to Antipneumococcal Vaccination of Children
ConclusionBefore introduction of PCV in the Polish NIP we noticed an unexpected increase of serotype 19A in invasive pneumococcal infections, with the most common being representatives of highly drug-resistant GPSC1/CC320 clone, rarely identified in Europe both before and even after PCV introduction. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - July 13, 2023 Category: Infectious Diseases Source Type: research
Improved Diagnostics in Bacterial Neonatal Meningitis Using a Next-Generation Sequencing Platform
ConclusionAddition of 16S rRNA sequencing to conventional culturing greatly improved the identification of the aetiology of bacterial meningitis compared to culturing of CSF samples alone. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - July 12, 2023 Category: Infectious Diseases Source Type: research
