Cefiderocol Versus Colistin for the Treatment of Carbapenem-Resistant Acinetobacter baumannii Complex Bloodstream Infections: A Retrospective, Propensity-Score Adjusted, Monocentric Cohort Study
ConclusionsCefiderocol may be a valuable treatment option for CRAB-BSI, especially in the current context of limited treatment options. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - September 1, 2023 Category: Infectious Diseases Source Type: research
Safety and Clinical Benefits of Adacel ® and Adacel®-Polio Vaccination in Pregnancy: A Structured Literature Review
In conclusion, Adacel or Adacel-Polio vaccination in pregnancy is highly effective in protecting young infants from pertussis disease, with a favorabl e safety profile for both pregnant women and their infants. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - September 1, 2023 Category: Infectious Diseases Source Type: research
Combination Therapy of Ceftazidime/Avibactam for the Treatment of Patients Infected with Carbapenem-Resistant Klebsiella pneumoniae: A Multicenter Retrospective Study
ConclusionCombination therapy (or CAZ/AVI combined with tigecycline) and monotherapy with CAZ/AVI had similar prognoses in patients with only CRKP infection (or CRKP-associated pneumonia), as well as in critically ill patients. Larger randomized controlled trials are warranted to confirm these findings. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - September 1, 2023 Category: Infectious Diseases Source Type: research
Cefiderocol Versus Colistin for the Treatment of Carbapenem-Resistant Acinetobacter baumannii Complex Bloodstream Infections: A Retrospective, Propensity-Score Adjusted, Monocentric Cohort Study
ConclusionsCefiderocol may be a valuable treatment option for CRAB-BSI, especially in the current context of limited treatment options. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - September 1, 2023 Category: Infectious Diseases Source Type: research
Safety and Clinical Benefits of Adacel ® and Adacel®-Polio Vaccination in Pregnancy: A Structured Literature Review
In conclusion, Adacel or Adacel-Polio vaccination in pregnancy is highly effective in protecting young infants from pertussis disease, with a favorabl e safety profile for both pregnant women and their infants. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - September 1, 2023 Category: Infectious Diseases Source Type: research
Combination Therapy of Ceftazidime/Avibactam for the Treatment of Patients Infected with Carbapenem-Resistant Klebsiella pneumoniae: A Multicenter Retrospective Study
ConclusionCombination therapy (or CAZ/AVI combined with tigecycline) and monotherapy with CAZ/AVI had similar prognoses in patients with only CRKP infection (or CRKP-associated pneumonia), as well as in critically ill patients. Larger randomized controlled trials are warranted to confirm these findings. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - September 1, 2023 Category: Infectious Diseases Source Type: research
Correction to: An Economic Evaluation Estimating the Clinical and Economic Burden of Increased Vancomycin-Resistant Enterococcus faecium Infection Incidence in Japan
(Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - August 27, 2023 Category: Infectious Diseases Source Type: research
An Updated Analysis of the Impact of HPV Vaccination Based on Long-term Effectiveness in the Netherlands
ConclusionsUpdated health economic models for HPV vaccination, using updated and long-term effectiveness data and including prevention of treatment-related side effects, demonstrate a substantial additional positive effect on vaccination outcomes. Indeed, extrapolation of the bivalent HPV vaccine ’s updated long-term effectiveness data against HPV-related cervical diseases shows that the positive effects of vaccination may be more substantial than previously estimated. There is a graphical abstract available for this article.Graphical Abstract (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - August 10, 2023 Category: Infectious Diseases Source Type: research
Comparing Real-World Healthcare Costs Associated with Single-Tablet Regimens for HIV-1: The 2-Drug Regimen Dolutegravir/Lamivudine vs. Standard 3- or 4-Drug Regimens
ConclusionDolutegravir/lamivudine had the lowest healthcare costs of BIC/FTC/TAF, EVG/COBI/FTC/TAF, and DRV/COBI/FTC/TAF, and the lowest pharmacy costs of all regimens, in unadjusted and adjusted analyses and by treatment experience, supporting the economic benefits of DTG/3TC as an initial or switch regimen for HIV-1. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - August 8, 2023 Category: Infectious Diseases Source Type: research
Metagenomic Next-Generation Sequencing for Pathogens in Bronchoalveolar Lavage Fluid Improves the Survival of Patients with Pulmonary Complications After Allogeneic Hematopoietic Stem Cell Transplantation
ConclusionsmNGS for BALF could facilitate accurate and fast diagnosis for pulmonary complications. Early mNGS could improve the prognosis of patients with pulmonary complications after allo-HSCT.Trial RegistrationClinicalTrials.gov identifier, NCT 04051372. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - August 4, 2023 Category: Infectious Diseases Source Type: research
