Correction: Epidemiological Changes and Improvement in Outcomes of Infective Endocarditis in Europe in the Twenty-First Century: An International Collaboration on Endocarditis (ICE) Prospective Cohort Study (2000 –2012)
(Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - December 1, 2023 Category: Infectious Diseases Source Type: research
Safety and Immunogenicity of Homologous Recombinant Adenovirus Type 5-Vectored COVID-19 Vaccine Booster Dose in Healthy Adults Aged 18–60 Years: a Single-Center, Open-Label Trial
ConclusionsA homologous booster of Ad5-nCoV vaccine is well tolerated and immunogenic in healthy adults aged 18 –60 years who had received a priming dose of Ad5-nCoV 6 months previously. The neutralizing antibodies against SARS-CoV-2 peaked at day 28 and specific T cell responses were noted at day 14 after booster. Ad5-nCoV vaccine can be considered as a homologous booster 6 months after a priming dos e.Trial registrationClinicalTrials.gov, NCT04568811. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - December 1, 2023 Category: Infectious Diseases Source Type: research
Factors Associated with Geographical Variability of Antimicrobial Use in Japan
ConclusionsIn this ecological study, the variability of total AMU by Japanese prefecture was associated with the proportion of female individuals, education level, and the number of URI diagnoses per population. The results suggest the potential need for additional stewardship efforts to reduce unnecessary antimicrobial prescriptions for URI. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - November 29, 2023 Category: Infectious Diseases Source Type: research
Podcast: Influenza-Associated Complications and the Impact of Vaccination on Public Health
In conclusion, influenza can cause a wide array of complications, which vaccination may help prevent.Podcast available for this article.Podcast: Influenza-associated complications and the impact of vaccination against influenza on public health (MP4 384341 KB) (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - November 23, 2023 Category: Infectious Diseases Source Type: research
Virologic Outcomes with Molnupiravir in Non-hospitalized Adult Patients with COVID-19 from the Randomized, Placebo-Controlled MOVe-OUT Trial
ConclusionsA 5-day course of orally administered molnupiravir demonstrated a consistently greater virologic effect than placebo, including rapidly eliminating infectious SARS-CoV-2, in high-risk outpatients with mild-to-moderate COVID-19.Trial RegistrationClinicalTrials.gov, NCT04575597. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - November 23, 2023 Category: Infectious Diseases Source Type: research
Epidemiology of Invasive Meningococcal Disease in Colombia: A Retrospective Surveillance Database Analysis
ConclusionThe overall incidence of IMD in Colombia was low but was highest among infants aged < 1 year. IMD cases tended to be concentrated in the more densely populated areas and in poorer neighborhoods. As the majority of IMD cases in Colombia since 2015 have been serogroup C, followed by B or Y, vaccination to protect against these serogroups could potentially be beneficial and help to a chieve the World Health Organization’s and Pan American Health Organization’s roadmaps to defeat meningitis by 2030.Graphical Abstract (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - November 15, 2023 Category: Infectious Diseases Source Type: research
Cabotegravir + Rilpivirine Long-Acting Injections for HIV Treatment in the US: Real World Data from the OPERA Cohort
ConclusionIn this large US cohort, most monthly CAB + RPV LA injections were administered on time and high levels of virologic control were achieved. These results suggest that CAB + RPB LA injectable can be administered effectively during routine clinical care. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - November 15, 2023 Category: Infectious Diseases Source Type: research
Epidemiology of Invasive Meningococcal Disease in Colombia: A Retrospective Surveillance Database Analysis
ConclusionThe overall incidence of IMD in Colombia was low but was highest among infants aged < 1 year. IMD cases tended to be concentrated in the more densely populated areas and in poorer neighborhoods. As the majority of IMD cases in Colombia since 2015 have been serogroup C, followed by B or Y, vaccination to protect against these serogroups could potentially be beneficial and help to a chieve the World Health Organization’s and Pan American Health Organization’s roadmaps to defeat meningitis by 2030.Graphical Abstract (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - November 15, 2023 Category: Infectious Diseases Source Type: research
Cabotegravir + Rilpivirine Long-Acting Injections for HIV Treatment in the US: Real World Data from the OPERA Cohort
ConclusionIn this large US cohort, most monthly CAB + RPV LA injections were administered on time and high levels of virologic control were achieved. These results suggest that CAB + RPB LA injectable can be administered effectively during routine clinical care. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - November 15, 2023 Category: Infectious Diseases Source Type: research
Candida albicans and Antifungal Peptides
AbstractCandida albicans, a ubiquitous opportunistic fungal pathogen, plays a pivotal role in human health and disease. As a commensal organism, it normally resides harmlessly within the human microbiota. However, under certain conditions,C. albicans can transition into a pathogenic state, leading to various infections collectively known as candidiasis. With the increasing prevalence of immunocompromised individuals and the widespread use of invasive medical procedures, candidiasis has become a significant public health concern. The emergence of drug-resistant strains further complicates treatment options, highlighting t...
Source: Infectious Diseases and Therapy - November 8, 2023 Category: Infectious Diseases Source Type: research
